Crude drug sample data base

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Crude drug name

Market name黒芥子 (ブラウンマスタード)
Formal name黒芥子
Japanese nameこくがいし, Kokugaishi
Latin nameSinapis Semen (CP)
English nameBlack Mustard Seed
Original plant nameBrassica nigra (L.) W. D. J. Koch, Kurogarashi
Family nameBrassicaceae
Used partClassificationPlant origin
Sub classification seed
Collection informationJapan, Osaka Pref., Tochimoto Tenkaido Co., Ltd.
Collection date1985/09/01
TMPW No.10150

The capital city, provincial capital city or the representative  
location of its administrative area is indicated.  
Production area information
https://ethmed.toyama-wakan.net/img/pin_san.png
34.6937378
135.50216509999996
Collection information
Japan,Osaka Pref.
https://ethmed.toyama-wakan.net/img/pin_nyu.png

Scientific information data base

Common name芥子, Jiezi, Sinapis Semen (CP2020), Mustard Seed (CP2020)
Synonyms白芥子, 黄芥子
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Original plant name白芥子<White Mustard Seed>: Brassica alba (L.) Boiss. (= Brassica hirta Moench)1;黄芥子<Yellow Mustard Seed>: Brassica juncea Coss. (= B. juncea Czern.)2, (Shirogarashi1, Karashi2)
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Family nameBrassicaceae
Used partseed
Quality for selectionGood Jiezi is as pungent as possible when chewed. (TN) Baijiezi (Jap. name: Byakugaishi) is said to be of higher quality.
Official compendiumCP (2020 ed.)
Clinical applicationAs a stimulant, rubefacient and expectorant, jiezi, defatted and pasted with water, is applied for neuritis and pneumonia transdermally. It is widely used as a raw material for spice and volatile mustard oil.
Medical systemTraditional Chinese medicine
Drug effect in
traditional medicine
Traditional
classification
Expectorants
Beneficial effect[Property and Flavor] Warm; pungent.
[Meridian Tropism] Lung meridian.
[Actions] To warm the lung and sweep phlegm, disinhibit qi, dissipate binds and unblock the collaterals to relieve pain.
[Indications] Cough with cold-phlegm, distending pain in the chest and the hypochondrium, phlegm stagnation in meridians, joint numbness and pain, phlegm-dampness deep multiple abscess,yin flat-abscesses with swelling and toxin.
Chemical constituentFatty acids
(*C2):
脂肪油/fatty oil 30~35%:
Erucic acid, Arachidic acid, Linolenic acid

Phenylpropanoids
B. juncea (*C1,C2):
Sinapic acid, Sinapine,

Glucosinolate
B. hirta (*C1):
Sinalbin 2.5~5%.(酵素 myrosinase により p-Hydroxybenzoyl isothiocyanateを生成)
B. juncea (*C1):
Sinigrin(酵素 myrosinase により Allyl isothiocyanate を生成)
B. nigra (*C1):
Sinigrin 1~2.5% (同上)

Others
B. juncea (*C1,C2):
Myrosinase

Chemical structure

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Pharmacological effectSkin and mucosal stimulation (mustard seed oil).
DNA sequenceAF264734, AF267640, M88342, AF128093, AF128094, D10840, X05060
Classical reference
(Chinese Herbal Classic "Zhenglei bencao")
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DiseaseNeuralgia, Pneumonia, Sputum, Cough, Swelling and pain of joint
FormulationSeishitsuketanto, Haiyoto
Related drugsBlack Mustard Seed
ReferencesCP2020: Pharmacopoeia of the People's Republic of China 2020 edi.
C1) The Encyclopedia of Wakan-Yaku with Color Pictures Vol. I, pp 232-233.
C2) Outline of Pharmacognosy, a Textbook, p 293.
Remarks Jiezi (Jap. name: Gaishi) had been listed in the Japanese Pharmacopoeia until 1971(8th revised edition). It defines the seed of B. juncea and congeners.
As a comprehensive term, Karashi, B. juncea (n=18), is amphidiploid, a natural cross between Aburana, B. rapa L (n=10), and Kurogarashi, B. nigra (L.) W. D. J. Koch (n=8). The place of its origin is said to be the Middle East or Central Asia.
In China, besides narrow-defined Karashi (var. juncea) which is the material for Jiezi, the following are also used as food.:
- Hakarashina (var. integrifolia Sinskaya or var. multisecta L. H. Bailey) is the pungent leaf or stem.
- Nekarashina (var. megarrhiza Tsen et Lee) is the root.
- Zāsai (var. tumida Tsen et Lee) is the swollen base of leaf-blade and petiole.
Kurogarashi is cultivated in the Middle East and Mediterranean region as a vegetable or medicinal plant like Karashi. The seed of Kurogarashi is called Kokugaishi.
Last renewal date2021/09/27