Crude drug sample data base
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Crude drug name | Market name | カノコソウ |
|---|---|---|
| Formal name | カノコソウ，吉草根 | |
| Japanese name | カノコソウ: かのこそう, Kanokosō, 吉草根: きっそうこん, Kissōkon | |
| Latin name | Valerianae fauriei Radix (JP) | |
| English name | Japanese Valerian (JP) | |
| Original plant name | Valeriana fauriei Briquet (f. yezoensis Hara), Kanokoso (Ezokanokoso) | |
| Family name | Valerianaceae | |
| Used part | Classification | Plant origin | Sub classification | root + rhizome |
| TMPW No. | 1115 | |
Scientific information data base
| Common name | カノコソウ, 吉草根, Kanokosō, Kissōkon, Valerianae Fauriei Radix (JP18), Japanese Valerian (JP18) | |||||
|---|---|---|---|---|---|---|
| Synonyms | 纈草根 | |||||
| crude drug image |
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| Original plant name | Valeriana fauriei Briquet1, (Kanokoso1, Ezokanokosō (Hokkaikissō)) | |||||
| original plant image |
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| Family name | Valerianaceae | |||||
| Used part | root and rhizome | |||||
| Quality for selection | Good Kanokosou has lots of palp-like roots. It is reddish brown. (TN) | |||||
| Official compendium | JP XVIII | |||||
| Clinical application | As an tranquilizer, antispasmodic and for expelling wind-cold, kanokosou is applied for hysteria and palpitation of the heart as fluid extract (up to 6g a day) or tincture (up to 1.5g a day). It is an ingredient of domestic medicine. | |||||
| Medical system | Traditional Chinese medicine | |||||
| Chemical constituent | Monoterpenoids V. fauriei 精油 [volatile oil] 1～8% (*C1, C2): Cineole, Camphene, Limonene, p-Cymene, Borneol, alpha-Pinene, beta-Pinene, Terpineol, Bornyl isovalerate（主成分約 [major constituent about] 90%）, Bornyl acetate V. fauriei Briq. f. yezoensis Hara (*C1): イリドイド配糖体/iridoid glycoside： Kanokoside A, Kanokoside B, Kanokoside C, Kanokoside D Sesquiterpenoids V. fauriei 精油 [volatile oil] 1～8% (*C1): alpha-Kessyl alcohol, alpha-Kessyl glycol, alpha-Kessylacetate, Kessoglycol, Kessazulene (Guaiazulene), Kessane, Kessanol, 8-epi-Kessanol, Valeranone(= Jatamansone), Kanokonol, Fauronyl acetate, Kanokonyl acetate, Cryptofauronol | |||||
| Chemical structure |    
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| Pharmacological effect | Sedative（kessoglycol diacetate, kessoglycol 2-acetate, kessoglycol 8-acetate)，antidepressant (alpha-kessyl alcohol, kessanol, cyclokessyl acetate)，suppression of stress-induced ulcer． | |||||
| DNA sequence | L13934, AJ236003 ; Traditioal Medical & Parmaceutical Database. | |||||
| Disease | Hysteria, Palpitation | |||||
| Formulation | ||||||
| Related drugs | Valerianae Rhizoma, Indian Valeriana (see "Remarks") | |||||
| References | JP18: The 18th edition of the Japanese Pharmacopoeia. C1)The Encyclopedia of Wakan-Yaku with Color Pictures Vol. I, pp 132-133. C2) Outline of Pharmacognosy, a Textbook，p223. C3) Nat. Med., 55, 225, 231(2001). | |||||
| Remarks | Valerianae Rhizoma: Root or rhizome of Valeriana officinale L. of family Valerianaceae (Jap. name: Seiyokanokoso). Indian Valeriana: Root or rhizome of V. wallichii DC. and others. "Kissokon" is the substitute for European Valerianae, which has been listed in The Japanese Pharmacopoeia since its first edition (1886). The plants of genus Valeriana are not used in China. A Japanese crude drug "Kanokoso", which circulates in the Japanese market, originates from Hokkaikisso (a kind of "Ezokanokoso"). "Hokkaikisso" consists of two varieties, Botan and Tako. There are considerable disparity in medicinal properties between the lineages. (C3) | |||||
| Last renewal date | 2021/09/27 | |||||
