Crude drug sample data base
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Crude drug name | Market name | 遠志 |
|---|---|---|
| Formal name | 遠志 | |
| Japanese name | おんじ, Onji | |
| Vernacular name | Yuanzhi | |
| Latin name | Polygalae Radix (JP), (CP) | |
| English name | Polygala Root (JP), Thinleaf Milkwort Root (CP) | |
| Original plant name | Polygala tenuifolia Willd., (Itohimehagi) | |
| Family name | Polygalaceae | |
| Used part | Classification | Plant origin | Sub classification | root |
| TMPW No. | 1161 | |
Scientific information data base
| Common name | 遠志, Yuanzhi, Polygalae Radix (JP18, CP2020), Polygala Root (JP18), Thinleaf Milkwort Root (CP2020) | |||||
|---|---|---|---|---|---|---|
| Synonyms | 大遠志，志通 | |||||
| crude drug image |
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| Original plant name | Polygala tenuifolia Willdenow (rarely Polygala sibirica Linn. ）, (Itohimehagi) | |||||
| original plant image |
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| Family name | Polygalaceae | |||||
| Used part | root or root bark | |||||
| Quality for selection | Good Yuanzhi is enlarged, thick and has irregular surface. Neither thin nor stiff one is good. (TN) | |||||
| Official compendium | JP XVIII, CP (2020 ed.) | |||||
| Clinical application | As a tranquilizer, expectorant and tonic, Yuanzhi is applied for forgetfulness, dream-disturbed sleep, cough, phlegm-heat and carbuncles. | |||||
| Medical system | Traditional Chinese medicine | |||||
| Drug effect in traditional medicine | Traditional classification | Sedatives and tranquilizer | ||||
| Beneficial effect | [Property and Flavor] Warm; bitter and pungent. [Meridian Tropism] Heart, kidney and lung meridians. [Actions] To tranquilize the mind and replenish wisdom, coordinate the heart and kidney, dispel phlegm, and disperse swelling. [Indications] Insomnia and dream-disturbed sleep, forgetfulness and fright palpitations caused by heart-kidney non-interaction pattern; absentmindedness, ungratifying expectoration of phlegm, sore and ulcer, swelling and toxin, breast swelling and pain. | |||||
| Chemical constituent | Monosaccharides (*C1): Polygalitol Triterpenoids (*C1): beta-Amyrin Triterpenoid saponins (*C1): Onjisaponin A(=Senegin IV), Onjisaponin B(=Senegin III), Onjisaponin C, Onjisaponin D, Onjisaponin E, Onjisaponin F, Onjisaponin G Phenylpropanoids (*C1): 3,4,5-Trimethoxycinnamic acid Xanthones (*C1): 3-Hydroxy-2,6,7,8-tetramethoxyxanthone, 2,6,7,8-Tetramethoxyxanthone, 2,3,6,7,8-Pentamethoxyxanthone Flavanones & Dihydroflavonols (*C1): Onsitin | |||||
| Chemical structure |   
※画像をクリックすると、拡大して表示されます。 | |||||
| Pharmacological effect | Inhibition of phosphodiesterase （onjisaponin B，E，F)，central nervous system inhibition （onjisaponin F). | |||||
| DNA sequence | U42797, L01945 | |||||
| Classical reference (Chinese Herbal Classic "Zhenglei bencao") |  ※Click this image to see the actual image | |||||
| Disease | Palpitation, Insomnia, Amnesia, Dementia, Cough, A lot of sputum, Pyogenic dermatosis | |||||
| Formulation | Kamiuntanto, Kamikihito, Kihito, Shoshinto, Ninjin-yoei-to, Ryukotsuto | |||||
| Related drugs | Senegae Radix | |||||
| References | JP18: The 18th edition of the Japanese Pharmacopoeia. CP2020: Pharmacopoeia of the People's Republic of China 2020 edi. C1)The Encyclopedia of Wakan-Yaku with Color Pictures Vol. I, pp 173-174. | |||||
| Remarks | The root bark without woody parts is called Yuanzhirou (遠志肉), Zhitong (志通) or Yuanzhitong (遠志筒), and considered to be superior in quality. | |||||
| Last renewal date | 2021/09/27 | |||||
