Crude drug sample data base
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The capital city, provincial capital city or the representative
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location of its administrative area is indicated.
Production area information
People's Republic of China
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34.6937378
135.50216509999996
Collection information
Japan,Osaka Pref.
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Scientific information data base
Common name | 遠志, Yuanzhi, Polygalae Radix (JP18, CP2020), Polygala Root (JP18), Thinleaf Milkwort Root (CP2020) | |||||
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Synonyms | 大遠志,志通 | |||||
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Original plant name | Polygala tenuifolia Willdenow (rarely Polygala sibirica Linn. ), (Itohimehagi) | |||||
original plant image |
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Family name | Polygalaceae | |||||
Used part | root or root bark | |||||
Quality for selection | Good Yuanzhi is enlarged, thick and has irregular surface. Neither thin nor stiff one is good. (TN) | |||||
Official compendium | JP XVIII, CP (2020 ed.) | |||||
Clinical application | As a tranquilizer, expectorant and tonic, Yuanzhi is applied for forgetfulness, dream-disturbed sleep, cough, phlegm-heat and carbuncles. | |||||
Medical system | Traditional Chinese medicine | |||||
Drug effect in traditional medicine | Traditional classification | Sedatives and tranquilizer | ||||
Beneficial effect | [Property and Flavor] Warm; bitter and pungent. [Meridian Tropism] Heart, kidney and lung meridians. [Actions] To tranquilize the mind and replenish wisdom, coordinate the heart and kidney, dispel phlegm, and disperse swelling. [Indications] Insomnia and dream-disturbed sleep, forgetfulness and fright palpitations caused by heart-kidney non-interaction pattern; absentmindedness, ungratifying expectoration of phlegm, sore and ulcer, swelling and toxin, breast swelling and pain. | |||||
Chemical constituent | Monosaccharides (*C1): Polygalitol Triterpenoids (*C1): beta-Amyrin Triterpenoid saponins (*C1): Onjisaponin A(=Senegin IV), Onjisaponin B(=Senegin III), Onjisaponin C, Onjisaponin D, Onjisaponin E, Onjisaponin F, Onjisaponin G Phenylpropanoids (*C1): 3,4,5-Trimethoxycinnamic acid Xanthones (*C1): 3-Hydroxy-2,6,7,8-tetramethoxyxanthone, 2,6,7,8-Tetramethoxyxanthone, 2,3,6,7,8-Pentamethoxyxanthone Flavanones & Dihydroflavonols (*C1): Onsitin | |||||
Chemical structure |
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Pharmacological effect | Inhibition of phosphodiesterase (onjisaponin B,E,F),central nervous system inhibition (onjisaponin F). | |||||
DNA sequence | U42797, L01945 | |||||
Classical reference (Chinese Herbal Classic "Zhenglei bencao") | ※Click this image to see the actual image | |||||
Disease | Palpitation, Insomnia, Amnesia, Dementia, Cough, A lot of sputum, Pyogenic dermatosis | |||||
Formulation | Kamiuntanto, Kamikihito, Kihito, Shoshinto, Ninjin-yoei-to, Ryukotsuto | |||||
Related drugs | Senegae Radix | |||||
References | JP18: The 18th edition of the Japanese Pharmacopoeia. CP2020: Pharmacopoeia of the People's Republic of China 2020 edi. C1)The Encyclopedia of Wakan-Yaku with Color Pictures Vol. I, pp 173-174. | |||||
Remarks | The root bark without woody parts is called Yuanzhirou (遠志肉), Zhitong (志通) or Yuanzhitong (遠志筒), and considered to be superior in quality. | |||||
Last renewal date | 2021/09/27 | |||||