Crude drug sample data base

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Crude drug name

Market name草烏頭
Formal name草烏頭
Japanese nameそううず, Sōuzu
Vernacular nameCaowutou
Latin nameAconiti Kusnezoffii Radix
English nameKusnezoff Monkshood Root, Aconite
Original plant nameAconitum kusnezoffii Reichb or Aconitum spp.
Family nameRanunculaceae
Used partClassificationPlant origin
Sub classification tuber
Production area informationPeople's Republic of China, Shaanxi Prov.
Collection informationRepublic of Korea, Seoul, Singdong Han Clinic
Collection date1976/11/01
TMPW No.137

The capital city, provincial capital city or the representative  
location of its administrative area is indicated.  
34.341574
108.93976999999995
Production area information
People's Republic of China,Shaanxi Prov.
https://ethmed.toyama-wakan.net/img/pin_san.png
37.566535
126.97796919999996
Collection information
Republic of Korea,Seoul
https://ethmed.toyama-wakan.net/img/pin_nyu.png

Scientific information data base

Common name烏頭, Wutou, Aconiti Radix (CP2020), Common Monkshood Mother Root (CP2020)
Synonyms川烏 (Chuanwu), 川烏頭 (Chuan wutou), 草鳥 (Caowu), 草烏頭 (Cao wutou)
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Original plant nameAconitum carmichaeli Debx.1Aconitum kusnezoffii Reichb.2, CN products: Karatorikabuto (Chuan wutou1, Cao wutou2), and etc.
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Family nameRanunculaceae
Used parttuber (parent root for chuanwu)
Quality for selectionThe bark of a good Wutou is black and the inside is white. (TN)
Official compendiumCP (2020 ed.)
Clinical applicationAs an antispasmodic and painkiller, Wutou is applied for arthritis, numbness of limbs and abdominal pain of sickly person. It is also used as diuretic and tonic.
Medical systemTraditional Chinese medicine
Drug effect in
traditional medicine
Traditional
classification
Drugs for dispelling internal cold
Beneficial effect[Property and Flavor] Hot; pungent, bitter; highly toxic.
[Meridian Tropism] Heart, liver, kidney and spleen meridians.
[Actions] To dispel wind and remove dampness, and warm the meridian to relieve pain.
[Indications] Wind cold dampness impediment, joint pain, cold pain in the heart and abdomen, pain in cold abdominal colic, and it can be applied for anesthesia to relieve pain. As it is highly poisonous, it is processed before use generally .
Chemical constituentAlkaloids
A. carmichaeli (*C1):
Aconitine, Hypaconitine, Mesaconitine, Carmichaeline, Talatisamine, Coryneine chloride
A. japonicum (*C1):
Aconitine, Mesaconitine, Hypaconitine, Hygenamine
Aconitum spp. (*C2):
アコニチン系:Aconitine, Hypaconitine, Mesaconitine, Jesaconitine, Neopelline,
アチシン系:Atisine, Kobusine, Pseudokobusine, Telatisine, Songorine, Atidine, Napelline, Heteratisine, Hypognavine, Ignavine,
強心成分/cardiac component:Hygenamine, Coryneine, Yokonoside, etc.
A. delavayii Franch. (*C1):
Delavaconitine
A. soongaricum (*C1):
Aconitine, Songorine (= napellonine), Acetylsongorine

Chemical structure





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Pharmacological effectSedation, suppression of stress ulcer (extract). Sedation, reduction of blood pressure, arrhythmogenic effect (aconitine), cardiotonic effect (hygenamine, coryneine). Analgesia, antiinflammation (mesaconitine).
DNA sequenceAB020369, AB020370, AB020371, AB020372, AB020373, AB020374
Classical reference
(Chinese Herbal Classic "Zhenglei bencao")
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DiseaseSomatic pain, Swelling and pain of joint, Numbness, Frequent urination, Abdominal pain, Numbness
FormulationUzuto, Uzukeishito, Uzushakusekisigan, Sanshoin, Sekiganryo (keihi), Sekiganryo (hange)
Related drugsFuzi, the daughter root of Aconitum carmichaeli.
ReferencesCP2020: Pharmacopoeia of the People's Republic of China 2020 edi.
C1)The Encyclopedia of Wakan-Yaku with Color Pictures Vol. I, pp 91-97.
C2)Outline of Pharmacognosy, a Textbook, pp 304-305.
Remarks- The tubers of wild Aconitum have respective names depending on the production area and species, as follows: Sōuzu (Jap. name), Caowu, Wuyao, Jinniuqi, Dacaowu, Xiaoheiniu, Xuewu, Huangcaowu, Tengcaowu, Wanwuyao, Kaenshi (Jap. name), Tiebangchui.
- Various kinds of Chinese Souzu: A. kusnezoffii (Heilongjiang), A. artemisaefolium Bar. et Skv. (Liaonig), A. paniculigerum Nakai, A. sczukini Turcz. (Northeast part), A. taipeicum Hand.-Mazz. (Shaanxi), A. karakolicum Rap., A. soongaricum Stapf (Xinjiang), A. sungpanense Hand.-Mazz. (Shaanxi, Gansu, Sichuan), A. hemsleyanum Pritz. (Sichuan, Hubei, Hunan, Shaanxi), A. stylosum Stapf, A. transsectum Diels, A. delavayi Franch. (Yunnan) and many other tubers of genus Aconitum.
- Korean Sōuzu: Tubers of several Aconitum genus such as A. triphyllum Nakai (Jap. name: Mitsubatorikabuto).
- Japanese Sōuzu: The tuber of A. japonicum Thunb.
- The Pharmacopoeia of The People's Republic of China contains Chuanwu, the parent root of A. carmichaeli (harvested from late June to early August), and Caowu, the tuber of A. kusnezoffii (harvested in Autumn). Caowu is stronger in both toxicity and benefit than Chuanwu. Compared with Fuzi, Wutou has advantages of expelling wind and relieving pain, and has disadvantages of stimulating heart and dispelling cold.
Last renewal date2022/11/02