Crude drug sample data base
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Scientific information data base
Common name | 訶子, Hezi, Chebulae Fructus (Non-JPS2022, CP2020), Myrobalan Fruit (Non-JPS2022), Medicine Terminalia Fruit (CP2020) | |||||
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Synonyms | 訶梨勒, Helile, Haritaki, A-ru, A-ru-la | |||||
crude drug image |
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Original plant name | Terminalia chebula Retzius, (Mirobaran, (Mirobarannoki)) | |||||
original plant image |
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Family name | Combretaceae | |||||
Used part | fruit | |||||
Quality for selection | Good Hezi has blackish pericarp and a lot of seeds. It tastes bitter. (NI) | |||||
Official compendium | Non-JPS (2022), CP (2020 ed.) | |||||
Clinical application | As an astringent, antidiarrheal drug, hemostatic and antitussive, Hezi is applied for chronic laryngitis, laryngeal tuberculosis, intestinal hemorrhage, hemorrhoids, uterine bleeding, chronic uterine inflammation, leukorrhea and all. | |||||
Medical system | Traditional Chinese medicine | |||||
Drug effect in traditional medicine | Traditional classification | Astringents and haemostatics | ||||
Beneficial effect | [Property and Flavor] Neutral; bitter, sour and astringent. [Meridian Tropism] Lung and large intestine meridians. [Actions] To astringe the intestines to check diarrhea, constrain the lung to suppress cough, downbear fire to soothe the throat. [Indications] Chronic diarrha and chronic dysentery, bloody stool and prolapse of the rectum, cough and panting caused by lung deficiency, chronic cough, sore throat and hoarseness. | |||||
Chemical constituent | Tannins (*C1): タンニン/tannins 20~40%: Ellagic acid, Gallic acid, Luteolic acid, Chebulic acid | |||||
Chemical structure |
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Pharmacological effect | Antibacterial (decoction: Staphylococcus aureus, Salmonella typhi), antivirus (extract: Herpes simplex, etc.), anti-HIV, anti-arteriosclerosis, immunomodulatory. | |||||
Classical reference (Chinese Herbal Classic "Zhenglei bencao") | ※Click this image to see the actual image | |||||
Disease | Diarrhea, Muddy and watery stool, Hematochezia due to proctoptosis, Dyspnea, Cough, Loss of voice, Hoarseness, Irregular vaginal bleeding, Leukorrhea, Frequent urination, Spermatorrhea | |||||
Formulation | Kyoseihatekigan | |||||
Related drugs | Maohezi (Bibhitaki, Ba-ru-la) | |||||
References | Non-JPS2022: The Japanese standards for non-Pharmacopoeial crude drugs 2022. CP2020: Pharmacopoeia of the People's Republic of China 2020 edi. C1)The Encyclopedia of Wakan-Yaku with Color Pictures Vol. I, pp 246-247. | |||||
Remarks | It is one of the important drugs of Ayurveda, traditional Indian medicine, and the crude drug name is Haritaki. There are seven kinds of Haritaki depending on its shape or locality. It is said that Vijaya, which is roundish and produced in Himalaya, is the best quality. In India, it is used to treat chronic constipation, chronic ulcer, apepsia, bronchitis, cough, asthma, hoarseness, diarrhea, parasite, hemorrhage, etc. The formulation which consists of Haritaki, Amalaki (Yuganzi in Chinese, Yokanshi in Japanese) and Bibhitaki (Maohezi in Chinese, Mokashi in Japanese) is called Triphala (a group of three fruits), and is used as powder medicine, drink and other forms for tonicity and anti-aging. Haritaki was introduced into Tibet. The crude drug name in Tibet is A-ru-la or A-ru. In Tibetan medicine, it is an all-purpose cure and the symbol of Medicinal Buddha. In China, it was listed in Xin Xin Ben Cao, published in Tang Dynasty, under the name of Helile (Kariroku in Japanese) at the first place. However, it might have been used earlier than that period. Kariroku had been carried to Japan in Nara Period by Jianzhen (Ganjin bonze). | |||||
Last renewal date | 2022/07/19 | |||||