Crude drug sample data base

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Crude drug name

Market name黒胡椒
Formal name黒胡椒
Japanese nameこしょう, Koshō
Latin namePiperis Fructus (CP), Piperis Nigri Fructus
English namePepper Fruit (CP)
Original plant namePiper nigrum L., (Koshō)
Family namePiperaceae
Used partClassificationPlant origin
Sub classification seed
Collection informationJapan, Osaka Pref., Mikuni Shoten
Collection date1957/00/00
IdentifierKatsuko Komatsu
TMPW No.2007

The capital city, provincial capital city or the representative  
location of its administrative area is indicated.  
Production area information
https://ethmed.toyama-wakan.net/img/pin_san.png
34.6937378
135.50216509999996
Collection information
Japan,Osaka Pref.
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Scientific information data base

Common name胡椒, Hujiao, Piperis Fructus (CP2020), Pepper Fruit (CP2020)
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Original plant namePiper nigrum Linn., (Koshō)
original plant image
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Family namePiperaceae
Used partBlack colored: immature fruit / White colored: mature fruit
Quality for selectionThe good one is fresh and large. It has a strong pungency. (TN)
Official compendiumCP (2020 ed.)
Clinical applicationAs a diaphoretic, carminative and stomachic, it is applied for indigestion, dyspepsia, vomiting, diarrhea and abdominal pain. It is taken orally or applied externally on the umbilicus as a plaster. Generally, white pepper is used as medicine.
Medical systemTraditional Chinese medicine
Drug effect in
traditional medicine
Traditional
classification
Drugs for dispelling internal cold
Beneficial effect[Property and Flavor] Hot, pungent.
[Meridian Tropism] Stomach and large intestine meridians.
[Actions] To warm the middle energizer energizer to dissipate cold, direct qi downward, resolve phlegm.
[Indications] Vomiting caused by stomach cold, abdominal pain caused by diarrhea, anepithyrnia, epilepsy and profuse sputum.
Chemical constituentMonoterpenoids
(*C1):
l-alpha-Phellandrene, alpha-Pinene, beta-Pinene, d-Limonene, l-Limonene, Linalool
(*C2):
delta-3-Carene, Myrcene, Limonene, Sabinene

Sesquiterpenoids
(*C1):
beta-Caryophyllene
(*C2):
beta-Caryophyllene, Caryophyllene oxide, delta-Cadinene

Other aromatic derivatives
(*C1):
Piperine, Chavicine, Piperyline, Piperoleine A, Piperoleine B

Chemical structure



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Pharmacological effectStimulating intestinal peristalsis, sedation, antiinflammatory, antimalarial (moderate effect), inducing GST (beta-caryophyllene), anticancer activity, inducing GST (caryophyllene oxide).
DNA sequenceAB040153, AF275197, AF275198, M82466, M82467, M82468, M82469, M82470, M82471
Classical reference
(Chinese Herbal Classic "Zhenglei bencao")
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DiseaseDyspepsia, Intestinal weakness, Vomiting, Upper abdominal pain, Anorexia, Diarrhea
Formulation
Related drugs"Marica" in Ayurveda, "Na-le-sham" in Tibetan Medicine
ReferencesCP2020: Pharmacopoeia of the People's Republic of China 2020 edi.
C1)The Encyclopedia of Wakan-Yaku with Color Pictures Vol. I, pp 295-296.
C2)J. Essent. Oil Res., 12, 603-608 (2000).
RemarksBlack pepper is the dried immature fruit. White pepper is the dried mature fruit after removing the epicarp. Black pepper: Eared immature fruits are harvested. Then the fruit is separated from the ear by hand kneading, immersed in boiling water until the surface turns to black, lifted from the water and dried. White pepper: Mature fruits are bagged and immersed in flowing water for a week. Then the pericarp and sarcocarp are removed. The remaining seed is dried. Alternatively, it is made by just removing the pericarp and sarcocarp of Black pepper. Hujiao originally came from Southern India to Europe in about B.C.400, and to China in Tang Dynasty. Hujiao opened the Age of Geographical Discovery (the era started by the discovery of shipping route to India). At the time, during late 15th to 16th century, its value was equivalent to gold.
Last renewal date2021/09/28