Crude drug sample data base
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Scientific information data base
Common name | 肉豆蔲, Roudoukou, Myristicae Semen (JP18, CP2020), Nutmeg (JP18, CP2020) | |||||
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Original plant name | Myristica fragrans Houttuyn, (Nikuzuku) | |||||
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Family name | Myristicaceae | |||||
Used part | seed (aril and seed coat) | |||||
Quality for selection | The cross section of good Roudoukou has bright marble-like striations. It is fresh and has a nice odor. (TN) | |||||
Official compendium | JHMC (1989), CP (2020 ed.), JP XVIII | |||||
Clinical application | As an aromatic stomachic and carminative, it is applied to treat indigestion, abdominal distension, abdominal pain, diarrhea, chronic colonitis, enteric tuberculosis. It is a raw material for "roudoukou-oil" and "roudoukou-fat". | |||||
Medical system | Traditional Chinese medicine | |||||
Drug effect in traditional medicine | Traditional classification | Astringents and haemostatics | ||||
Beneficial effect | [Property and Flavor] Warm; pungent. [Meridian Tropism] Spleen, stomach and large intestine meridians. [Actions] To warm the middle energizer and move qi, astringe the intestines to check diarrhea. [Indications] Spleen-stomach deficiency cold, chronic diarrhea, distending pain in the epigastrium and abdomen, reduced food intake, vomiting. | |||||
Chemical constituent | Fatty acids (*C1): Myristic acid Lipids (*C1): Oleic acidその他のglyceride, Trimyrisate Monoterpenoids (*C1): d-Camphene, d-alpha-Pinene, Dipentene, d-Borneol, l-Terpineol, Geraniol (*C7): d-Linalool, d-beta-Pinene, dl-Limonene Phenylpropanoids (*C1): Safrole, Myristicin, Acyclic bis-phenylproponoides M. fragrans (*C2,C3,C4,C5,C6): erythro-2-(4"-Allyl-2",6"-dimethoxyphenoxy)-1-(3',4',5'-trimethoxyphenyl)propan-1,3-diol, Fragransol-C, Fragransol-D, Myristicanol-A, Myristicanol-B, 2-(4-Allyl-2,6-dimethoxyphenoxy)-1-(4-hydroxy-3-methoxyphenyl)propane, erythro-2-(4-Allyl-2,6-dimethoxyphenoxy)-1-(3-hydroxy-4,5-dimethoxyphenyl)propan-1-ol, erythro-2-(4-Allyl-2,6-dimethoxyphenoxy)-1-(4-hydroxy-3,5-dimethoxyphenyl)propan-1-ol, erythro-2-(4-Allyl-2,6-dimethoxyphenoxy)-1-(4-hydroxy-3-methoxyphenyl)-1-methoxypropane, threo-2-(4-Allyl-2,6-dimethoxyphenoxy)-1-(4-hydroxy-3-methoxyphenyl)-1-methoxypropane, threo-2-(4-Allyl-2,6-dimethoxyphenoxy)-1-(4-hydroxy-3-methoxyphenyl)propan-1-ol, erythro-2-(4-Allyl-2-methoxyphenoxy)-1-(4-hydroxy-3-methoxyphenyl)propan-1-ol, threo-2-(4"-Allyl-2"-methoxyphenoxy)-1-(4'-hydroxy-3'-methoxyphenyl)propan-1-ol, trans-2,3-Dihydro-7-methoxy-2-(3,4-methoxyphenyl)-3-methyl-5-(1-(E)-propenyl)benzofuran, 2,3-Dimethyl-1,4-bis-(3,4-methylenedioxyphenyl)butan-1-ol, Fragransin A2 Fragransin B1, Fragransin B2, Fragransin B3, Fragransin C1, Fragransin C2, Fragransin C3a, Fragransin C3b, Fragransin D1, Fragransin D2, Fragransin D3, Fragransin E1, Fragransol-A, Fragransol-B, thero-1-(4-Hydroxy-3,5-dimethoxyphenyl)-2-(2-methoxy-4-(1(E)-propenyl)phenoxy)propan-1-ol, erythro-1-(4'-Hydroxy-3'-methoxyphenyl)-2-(2"-methoxy-4"-(1'''(E)-propenyl)phenoxy)propan-1-ol, threo-1-(4'-Hydroxy-3'-methoxyphenyl)-2-(2"-methoxy-4"-(1'''(E)-propenyl)phenoxy)propan-1-ol | |||||
Chemical structure |
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Pharmacological effect | Low dose: appetizer. High dose: headache, dizziness, lethargy, hallucination. | |||||
DNA sequence | AF197768, AF206968 | |||||
Classical reference (Chinese Herbal Classic "Zhenglei bencao") | ※Click this image to see the actual image | |||||
Disease | Muddy and watery stool, Proctoptosis, Diarrhea, Abdominal pain, Full stomach, Vomitting | |||||
Formulation | rarely used in formula | |||||
References | JP18: The 18th edition of the Japanese Pharmacopoeia. CP2020: Pharmacopoeia of the People's Republic of China 2020 edi. C1) The Encyclopedia of Wakan-Yaku with Color Pictures Vol. I, pp 241-242. C2) Phytochemistry,27,563(1988). C3) Chem.Pharm.Bull.,36,648(1988). C4) Chem.Pharm.Bull.,35,668(1987). C5) Chem.Pharm.Bull.,34,3885(1986). C6) Chem.Pharm.Bull.,35,3315(1987). C7) Outline of Pharmacognosy, a Textbook, pp 310-311. | |||||
Remarks | The following are similar products. "Chōkeinikuzuku" (Macassar Nutmeg, Papua Nutmeg): Myristica argentea Warburg, produced in Indonesia or New Guinea. "Indonikuzuku" (Bombay Nutmeg): Myristica malabarica Lam., produced in India. Since both contain a small amount of essential oil, the quality is inferior. | |||||
Last renewal date | 2021/09/27 | |||||