Crude drug sample data base

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Crude drug name

Market name肉豆蔲
Formal name肉豆蔲
Japanese nameにくずく, Nikuzuku
Vernacular nameRoudoukou
Latin nameMyristicae Semen (JP), (CP)
English nameNutmeg (JP), (CP)
Other namesナツメグ
Original plant nameMyristica fragrans Houtt., Nikuzuku, Nutmeg
Family nameMyristicaceae
Used partClassificationPlant origin
Sub classification seed
Collection informationHong Kong, Wing Tai Hong Medicine Co.,Ltd.
Collection date1974/12/25
TMPW No.2112

Scientific information data base

Common name肉豆蔲, Roudoukou, Myristicae Semen (JP18, CP2020), Nutmeg (JP18, CP2020)
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Original plant nameMyristica fragrans Houttuyn, (Nikuzuku)
original plant image
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Family nameMyristicaceae
Used partseed (aril and seed coat)
Quality for selectionThe cross section of good Roudoukou has bright marble-like striations. It is fresh and has a nice odor. (TN)
Official compendiumJHMC (1989), CP (2020 ed.), JP XVIII
Clinical applicationAs an aromatic stomachic and carminative, it is applied to treat indigestion, abdominal distension, abdominal pain, diarrhea, chronic colonitis, enteric tuberculosis. It is a raw material for "roudoukou-oil" and "roudoukou-fat".
Medical systemTraditional Chinese medicine
Drug effect in
traditional medicine
Traditional
classification
Astringents and haemostatics
Beneficial effect[Property and Flavor] Warm; pungent.
[Meridian Tropism] Spleen, stomach and large intestine meridians.
[Actions] To warm the middle energizer and move qi, astringe the intestines to check diarrhea.
[Indications] Spleen-stomach deficiency cold, chronic diarrhea, distending pain in the epigastrium and abdomen, reduced food intake, vomiting.
Chemical constituentFatty acids
(*C1):
Myristic acid

Lipids
(*C1):
Oleic acidその他のglyceride, Trimyrisate

Monoterpenoids
(*C1):
d-Camphene, d-alpha-Pinene, Dipentene, d-Borneol, l-Terpineol, Geraniol
(*C7):
d-Linalool, d-beta-Pinene, dl-Limonene

Phenylpropanoids
(*C1):
Safrole, Myristicin, Acyclic bis-phenylproponoides
M. fragrans (*C2,C3,C4,C5,C6):
erythro-2-(4"-Allyl-2",6"-dimethoxyphenoxy)-1-(3',4',5'-trimethoxyphenyl)propan-1,3-diol, Fragransol-C, Fragransol-D, Myristicanol-A, Myristicanol-B, 2-(4-Allyl-2,6-dimethoxyphenoxy)-1-(4-hydroxy-3-methoxyphenyl)propane, erythro-2-(4-Allyl-2,6-dimethoxyphenoxy)-1-(3-hydroxy-4,5-dimethoxyphenyl)propan-1-ol, erythro-2-(4-Allyl-2,6-dimethoxyphenoxy)-1-(4-hydroxy-3,5-dimethoxyphenyl)propan-1-ol, erythro-2-(4-Allyl-2,6-dimethoxyphenoxy)-1-(4-hydroxy-3-methoxyphenyl)-1-methoxypropane, threo-2-(4-Allyl-2,6-dimethoxyphenoxy)-1-(4-hydroxy-3-methoxyphenyl)-1-methoxypropane, threo-2-(4-Allyl-2,6-dimethoxyphenoxy)-1-(4-hydroxy-3-methoxyphenyl)propan-1-ol, erythro-2-(4-Allyl-2-methoxyphenoxy)-1-(4-hydroxy-3-methoxyphenyl)propan-1-ol, threo-2-(4"-Allyl-2"-methoxyphenoxy)-1-(4'-hydroxy-3'-methoxyphenyl)propan-1-ol, trans-2,3-Dihydro-7-methoxy-2-(3,4-methoxyphenyl)-3-methyl-5-(1-(E)-propenyl)benzofuran, 2,3-Dimethyl-1,4-bis-(3,4-methylenedioxyphenyl)butan-1-ol, Fragransin A2
Fragransin B1, Fragransin B2, Fragransin B3, Fragransin C1, Fragransin C2, Fragransin C3a, Fragransin C3b, Fragransin D1, Fragransin D2, Fragransin D3, Fragransin E1, Fragransol-A, Fragransol-B, thero-1-(4-Hydroxy-3,5-dimethoxyphenyl)-2-(2-methoxy-4-(1(E)-propenyl)phenoxy)propan-1-ol, erythro-1-(4'-Hydroxy-3'-methoxyphenyl)-2-(2"-methoxy-4"-(1'''(E)-propenyl)phenoxy)propan-1-ol, threo-1-(4'-Hydroxy-3'-methoxyphenyl)-2-(2"-methoxy-4"-(1'''(E)-propenyl)phenoxy)propan-1-ol

Chemical structure


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Pharmacological effectLow dose: appetizer. High dose: headache, dizziness, lethargy, hallucination.
DNA sequenceAF197768, AF206968
Classical reference
(Chinese Herbal Classic "Zhenglei bencao")
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DiseaseMuddy and watery stool, Proctoptosis, Diarrhea, Abdominal pain, Full stomach, Vomitting
Formulationrarely used in formula
ReferencesJP18: The 18th edition of the Japanese Pharmacopoeia.
CP2020: Pharmacopoeia of the People's Republic of China 2020 edi.
C1) The Encyclopedia of Wakan-Yaku with Color Pictures Vol. I, pp 241-242.
C2) Phytochemistry,27,563(1988).
C3) Chem.Pharm.Bull.,36,648(1988).
C4) Chem.Pharm.Bull.,35,668(1987).
C5) Chem.Pharm.Bull.,34,3885(1986).
C6) Chem.Pharm.Bull.,35,3315(1987).
C7) Outline of Pharmacognosy, a Textbook, pp 310-311.
RemarksThe following are similar products. "Chōkeinikuzuku" (Macassar Nutmeg, Papua Nutmeg): Myristica argentea Warburg, produced in Indonesia or New Guinea. "Indonikuzuku" (Bombay Nutmeg): Myristica malabarica Lam., produced in India. Since both contain a small amount of essential oil, the quality is inferior.
Last renewal date2021/09/27