Crude drug sample data base

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Crude drug name

Market nameWoan Manawek
Formal nameWan ma ha mek
Other namesKhamin-dam
Original plant nameCurcuma aeruginosa Roxb.
Family nameZingiberaceae
Used partClassificationPlant origin
Sub classification rhizome
Collection informationKingdom of Thailand, Bangkok, Jatujak Market Gardening Store 2
Collection date2002/11/10
CollectorKatsuko Komatsu
IdentifierKatsuko Komatsu
TMPW No.22069

The capital city, provincial capital city or the representative　　
location of its administrative area is indicated.　　
Production area information
https://ethmed.toyama-wakan.net/img/pin_san.png
13.7563309
100.50176510000006
Collection information
Kingdom of Thailand,Bangkok
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Scientific information data base

Crude drug nameThai name,
English name		Wan-ma-ha-mek
crude drug image
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Original plant nameCurcuma aeruginosa Roxb.
Family nameZingiberaceae
Used partRhizome
Distribution areaFound in India, Sri Lanka and Southeast Asia.
Frequency in useModerate to frequent.
Traditional usageThe rhizome is spicy, anti-flatulent, carminative, laxative and anti-diarrhoeal/anti-diarrheal.
Its maceration is used for allaying uteritis, uterus pain, bruise and muscle pain. It is also effective in shrinking the womb size after childbirth.
Drug effectAnti-flatulent, Carminative.
Chemical constituentTerpenoids (Essential oils)
camphor, camphene, α-Pinene, β-Caryophyllene, menthol, α-terpineol, α-phellandrene, 1-methyl-4-(1-methylethyl)-1,4-cyclohexadiene, 2-undecanone, Isocaryophyllene, β-myrcene, Isoborneol, Isoborneol acetate, β-pinene, limonene, eucalyptol, borneol, 2-nonanol, 2-nonanone, (E)-3,7-eimethyl-1,3,6-octatriene, copaene, 1,8-cineol, 2-tetradecanol, α-caryophyllene, 3-carene, curdione, α-cubebene, curzerene, β-sesquiphellandrene, curzerenone, 4-carene, γ-elemene, β-elemene, epizonarene.


Aerugidiol, borneol, borneol,iso, camphene, caryophyllene, caryophyllene,epoxy, 1,8-cineol, curcumene, curcumenol, curcumenol,iso, curcumin, curcumin,bis-demethoxy, curcumin,demethoxy, curdione, curdione, dehydro, curzerenone, curzerenone C, furanodienone, furanogemenone, germacrone, (+)-germacrone-4(S)-5(S)-epoxide, (+)-germacrone-4-5-epoxide, limonene, α-pinene, β-pinene, terpinene, turmerone, amylase, AR-turmerone, zederone, zedoalactone A, zedoalactone B, zedoarondiol, Curdione..

Pharmacological effectInhibiting HIV protease, antiviral, treating peptic ulcer, antihepatotoxicity, contraceptive, PAF antagonists.
The chloroform extract showed the potent P-gp inhibitory activity, when treated together with daunomycin.
The extract could increase the cytotoxic activity of daunomycin.
Curdione shows antimicrobial effect against Escherichia coli, Salmonella typhi, Klebsiella pneumoniae and Staphylococcus aureus.
The essential oil showed repellent activity.
DNA sequenceDQ438037, DQ438047, DQ471966, AB261849.
Medical systemThai medicine
PreparationsMaceration of the rhizome.
ReferencesReference book　

Tips！

The Forest Herbarium of the Royal Forest Department: Thai Plant Names Tem Smitinand, Revised Edition 2001. Prachachon Co.Ltd., Bangkok.
p 159.

Wuttidhamvate W.: Saranukrom Samunplai, 1997. Odian Store Press, Bangkok.
p 409.

Faculty of Pharmacy, Mahidol University.: Samunplai-Mai-Peun-Bann, vol IV. Bunyapraphatsara N and Choakchaijarenporn O, editors. 2000. Prachachon Co., Ltd., Bangkok.
pp 347-349.

Research paper1. (PMID: 15693713)
2. Takano I, Yasuda I, Takeya K, Itokawa H.: Guaiane sesquiterpene lactones from Curcuma aeruginosa. Phytochemistry. 1995;40(4): 1197-1200.
3. Ranjini CE, Vijayan KK.: A high amylose starch isolated from the tubers of Curcuma aeruginosa. Indian Journal of Chemistry. 2006;45B(12):2773-2775.
4. Jarikasem S,Thubthimthed S, Chawananoraseth K, Suntorntanasat T.: Essential Oil from Three Curcuma species collected in Thailand. ISHS Acta Horticulturae 677: III WOCMAP Congress on Medicinal and Aromatic Plants - Volume 3: Perspectives in Natural Product Chemistry
5. Kim HR; Chung SY, Jeong YH, Go EJ, Han AR, Kim NH, Min KS, Song G, Jang JO, Nam JW, Lee HJ; Seo EK.: P-glycoprotein inhibitory activity of Indonesian medicinal plants in human breast cancer cells. Natural Product Sciences. 2004;10(6):268-271.
6. Van NH, Phan MG, Phan TS.: Contribution to the study on substances having antibacterial activity from the rhizomes of Curcuma aeruginosa Roxb. Tap Chi Hoa Hoc. 1997;35(2):52-56.
7. Phan MG, Van NH, Phan TS.: Antimicrobial activity of sesquiterpene constituents from some Curcuma species of Vietnam. Tap Chi Hoa Hoc. 2000;38(1):91-94.
8. (PMID: 14714673)
Last renewal date2022/06/09
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