Crude drug sample data base

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Crude drug name

Market name唐桑白皮
Formal name桑白皮
Japanese nameそうはくひ, Sōhakuhi
Vernacular nameSangbaipi
Latin nameMori Cortex (JP), (CP)
English nameMulberry Bark (JP), White Mulberry Root-bark (CP)
Original plant nameMorus alba L., Maguwa (Tōguwa, Shiroguwa, Karayamaguwa)
Family nameMoraceae
Used partClassificationPlant origin
Sub classification root bark
Collection informationJapan, Osaka Pref., Tochimoto Tenkaido Co., Ltd.
Collection date1972/04/13
TMPW No.2422

The capital city, provincial capital city or the representative  
location of its administrative area is indicated.  
Production area information
https://ethmed.toyama-wakan.net/img/pin_san.png
34.6937378
135.50216509999996
Collection information
Japan,Osaka Pref.
https://ethmed.toyama-wakan.net/img/pin_nyu.png

Scientific information data base

Common name桑白皮, Sangbaipi, Mori Cortex (JP18, CP2020), Mulberry Bark (JP18), White Mulberry Root-bark (CP2020)
Synonyms亳桑皮: 河南,安徽/麗桑皮: 浙江/北桑皮: 江蘇
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Original plant nameMorus alba Linn., Morus mongolica (Bureau) Schneider, etc., (Maguwa (Tōguwa, Shiroguwa, Karayamaguwa), Mōkoguwa etc.)
original plant image
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Family nameMoraceae
Used partroot bark
Quality for selectionThe outer surface of good Sangbaipi is thin and yellowish-red. Also, there are bleached white Sangbaipis. (TN)
Official compendiumJP XVIII, CP (2020 ed.)
Clinical applicationAs an antitussive, expectorant, antiphlogistic diuretic, Sangbaipi is applied for bronchitis, cough, oliguria and edema.
Medical systemTraditional Chinese medicine
Drug effect in
traditional medicine
Traditional
classification
Antitussives and antiasthmatics
Beneficial effect[Property and Flavor] Cold; sweet.
[Meridian Tropism] Lung meridian.
[Actions] To purge the lung and relieve panting, and promote urination to alleviate edema.
[Indications] Panting and cough caused by lung-heat, edema, distention and fullness and small quantity of urination, puffiness.
Chemical constituentFatty acids
(*C1,C2):
Palmitic acid, Stearic acid

Triterpenoids
(*C1,C2):
alpha-Amyrin, alpha-Amyrin acetate, beta-Amylin, Betulinic acid

Sterols
(*C1,C2):
Sitosterol, Sitosterol-d-glucoside

Flavonoids
(*C1,C2):
Morusin, Cyclomorusin, Kuwanon A, Kuwanon B, Kuwanon C, Kuwanon D, Kuwanon E, Kuwanon F, Kuwanon G (Moracenin B, Albanin F), Kuwanon H (Moracenin A, Albanin G), Moracenin類, Oxydihydromorusin (=morusinol)
(*C3):
Kuwanon C, Kuwanon G, Kuwanon E, Kuwanon H, Kuwanon L, Morusin, Sanggenon D, Sanggenon C

Coumarins
(*C1,C2):
Umbelliferone, Scopoletin

Amino acids
(*C1):
Betaine

Other nitrogen compounds
(*C1):
Adenine

Chemical structure




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Pharmacological effectAnalgesia, cathartic, antiinflammatory (water soluble fraction), mild anti-tumor (hot water extractable fraction). Decrease in blood sugar (decoction, ethanol extract).
DNA sequenceD86319, L01933, L24398; Traditioal Medical & Parmaceutical Database.
Classical reference
(Chinese Herbal Classic "Zhenglei bencao")
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DiseaseBronchitis, Cough, Dyspnea, Rapid breathing, Edema, Oliguria
FormulationOgibekkoto, Kagaisan, Kagenshahakusan, Kikyoto, Kippihangeto, Kyososan, Gokoto, Shisoshito, Shahakusan, Seihaito, Zenshikunshito, Zosonmokuboito, Teizento, Dosuibukuryoto, Dotaitsukeito, Tonsonto, Ninjin-yoei-to, Baimoto, Hakanto, Bunshinkiin, Henseishinkiin, Boisan, Boito, Hontonto, Hontonto, Hontonto, Hontonbukuryoto, Mankeishisan, Yohaito
Related drugsMori Fructus, Mori Folium
ReferencesJP18: The 18th edition of the Japanese Pharmacopoeia.
CP2020: Pharmacopoeia of the People's Republic of China 2020 edi.
C1)The Encyclopedia of Wakan-Yaku with Color Pictures Vol. II, pp 153-154.
C2)Outline of Pharmacognosy, a Textbook, p 319.
C3)Nat. Med., 48, 75-81(1994).
Remarks- Sōjin (桑椹, the fruit of M. alba, Jap. name: Maguwa): Invigorates liver and kidney and restores the blood of Yin nature. It is applied for irritability and restlessness and insomnia, buzzing, lumbago and weakness in knee as a tonifying or analgesic drug.
- Sōyō (桑葉, the leaf of Maguwa): Reduces fever, antitussive, removes heat from the blood and improves vision. It is used to treat common cold, cough, headache, eye problem, beriberi, edema, abdominal pain and diarrhea. The name Kuwa is a generic name. About ten species are known as Kuwa, though some researchers claim more than twenty. There are many kinds of cultivated Kuwa which includes hybrid origin.
M. alba (Jap. name: Maguwa) is native of China and widely cultivated as feed for silkworm.
M. australis Poir. (Jap. name: Yamaguwa) is widely distributed from Himalaya region through Japan.
There is a view that classifies Yamaguwa into the following two species.: One is M. australis Poir. has a large leaf, which is distributed in Japan and Korean Peninsula, and the other is M. bombycis Koidz. (Jap. name: Shimaguwa) has a small lustrous leaf, which is distributed from southern Kyusyu (Japan) through eastern India.
Japanese Sangbaipi is the root bark of Yamaguwa or hybrid between Yamaguwa and Maguwa. At present, they have low marketability. The superior one is collected in spring, before germination, and processed.
Last renewal date2021/09/27