Crude drug sample data base

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Crude drug name

Market name漢防已
Formal name防已
Japanese nameぼうい, Bōi
Vernacular nameBōi
Latin nameSinomeni Caulis et Rhizoma (JP)
English nameSinomenium Stem and Rhizome (JP)
Original plant nameSinomenium acutum Rehder et Wilson, (Ōtsuzurafuji)
Family nameMenispermaceae
Used partClassificationPlant origin
Sub classification root
Production area informationJapan
TMPW No.246

Scientific information data base

Common name防已 (日本産/JP production), Bōi, Sinomeni Caulis et Rhizoma (JP18), Sinomenium Stem and Rhizome (JP18)
Synonyms漢防已, 青風藤, 青藤
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Original plant nameSinomenium acutum Rehder et E. H. Wilson, (Ōtsuzurafuji)
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Family nameMenispermaceae
Used partvine and rhizome
Quality for selectionThe cross section is brown and has a pattern of chrysanthemum. The real one resembles Mutong (木通: Akebia Stem). (TN)
Official compendiumJP XVIII, CP (2020 ed.)
Clinical applicationAs diuretic and anodyne, it is applied to treat nerve pain, rheumatism, arthritis and edema.
Medical systemTraditional Chinese medicine
Drug effect in
traditional medicine
Traditional
classification
Antirheumatics (dampness-eliminating)
Beneficial effect[Property and Flavor] Neutral; bitter and pungent.
[Meridian Tropism] Liver and spleen.
[Actions] To dispel wind-dampness, unblock the meridians and collateral vessels, promote urination.
[Indications] Painful impediment caused by wind-dampness, joint swelling, numbness and itching.
Chemical constituentSterols
S. acutum (*C1):
beta-Sitosterol, Stigmasterol

Isoquinoline alkaloids
S. acutum (*C1):
Sinomenine, Disinomenine, Isosinomenine, Sinactine, Tuduranine, Acutumine, Acutumidine, Sinoacutine, Magnoflorine
C. trilobus (*C1):
Trilobine, Isotrilobine, Homotrilobine, Trilobamine, Normenisarine, Cocculolidine, Magnoflorine

Chemical structure



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Pharmacological effectAntiinflammatory,antiallergic (hot water extract),antiinflammatory,analgesic,and decreases blood pressure(sinomenine).
DNA sequenceTraditioal Medical & Parmaceutical Database.
Classical reference
(Chinese Herbal Classic "Zhenglei bencao")
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DiseaseRheumatism, Arthritis, Arthralgia, Numbness, Thirst, Edema, Pulmonary edema, Ascites, Oliguria, Itching
FormulationOrenshodokuin, Shozokumeito, Jokinritsuansan, Seishitsuto, Zosonmokuboito, Sokeikakketsuto, Haikanpo, Boisan, Boito, Boiogito, Boijioto, Boibukuryoto, Mokuboito, Mokuboikyosekkokabukuryoboshoto, Rokumotsubushito
Related drugsMufangji,Fenfangji,Guangfangji (see "Remarks")
ReferencesJP18: The 18th edition of the Japanese Pharmacopoeia.
CP2020: Pharmacopoeia of the People's Republic of China 2020 edi.
C1)The Encyclopedia of Wakan-Yaku with Color Pictures Vol. I, pp 78-81.
Remarks"Mokuboi" (Jap. Name) is the stem or roots of Cocculus trilobus (Thunb.) DC. of family Menispermaceae. The Japanese Pharmacopoeia defines "Boi" (Fangji) as the climbing stem and rhizome of Sinomenium acutum Rehder et E.H. Wilson.
In China, the climbing stem of S. acutum or S. acutum (Thunb.) Rehder et Wilson var. cinereum Rehder et Wilson is called "Qingfengteng (青風藤)", which is enrolled in the Pharmacopoeia of People's Republic of China(CP).
"Fangji", which is also called ”Fenfangji (粉防已)", listed in the CP and it refers the root of Stephania tetrandra S. Moore of family Menispermaceae. "Guangfangji (広防已)" was listed in the CP and it referred the root of Aristolochia fangchi Y.C.Wu ex L.D.Chou ex S.M.Hwang of family Aristolochiaceae.
Last renewal date2023/03/23