Crude drug sample data base

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Crude drug name

Market name木防已
Formal name防已
Japanese nameぼうい, Bōi
Vernacular nameFangji
Original plant nameCocculus trilobus (Thunb.) DC. [not clearly identified], (Aotsuzurafuji) [not clearly identified]
Family nameMenispermaceae
Used partClassificationPlant origin
Sub classification caulis + rhizome
Production area informationPeople's Republic of China, Shaanxi Prov.
TMPW No.250

The capital city, provincial capital city or the representative  
location of its administrative area is indicated.  
34.341574
108.93976999999995
Production area information
People's Republic of China,Shaanxi Prov.
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Collection information
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Scientific information data base

Common name防已 (中国産/CN production), Fangji, Stephaniae Tetrandrae Radix (CP2020), Fourstamen Stephania Root (CP2020)
Synonyms粉防已, 漢防已, 瓜防已
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Original plant nameStephania tetrandra S. Moore (広防已 [Guangfangji]: Aristolochia fanchi Y.C.Wu ex L.D.Chou et S.M.Hwang), (Shimahasunohakazura)
Family nameMenispermaceae
Used partroot
Official compendiumCP (2020 ed.)
Clinical applicationAs diuretic and anodyne, it is applied to treat nerve pain, rheumatism, arthritis and edema.
Medical systemTraditional Chinese medicine
Drug effect in
traditional medicine
Traditional
classification
Antirheumatics (dampness-eliminating)
Beneficial effect[Property and Flavor] Cold; bitter.
[Meridian Tropism] Bladder and lung meridians.
[Actions] To dispel wind and relieve pain, and promote urination to alleviate edema.
[Indications] Painful impediment caused by wind-dampness, edema and beriberi, inhibited urination, eczema, sore and toxin.
Chemical constituentSesquiterpenoids
A. fangchi (*C1):
Aristolochic acid-I

Isoquinoline alkaloids
S. tetrandra (*C1):
Tetrandrine, Dimethyltetrandrine, Fangchinoline

Chemical structure


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Pharmacological effectAntiinflammatory,analgesic,diuretic, antihypertensive, and anti ACE effect (bisbenzylisoquinoline alkaloids).
DNA sequenceAJ303202, AF206855, L12630, L24083; Traditioal Medical & Parmaceutical Database.
Classical reference
(Chinese Herbal Classic "Zhenglei bencao")
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DiseaseRheumatism, Arthritis, Arthralgia, Thirst, Edema, Pulmonary edema, Ascites, Beriberi, Eczema, Oliguria, Hypertension, Skin disease
FormulationOrenshodokuin, Shozokumeito, Jokinritsuansan, Seishitsuto, Zosonmokuboito, Sokeikakketsuto, Haikanpo, Boisan, Boito, Boiogito, Boijioto, Boibukuryoto, Mokuboito, Mokuboikyosekkokabukuryoboshoto, Rokumotsubushito
Related drugsBoi (produced in Japan), Qingfengteng, Mufangji, Guangfangji, Hanzhongfangji (see "Remarks")
ReferencesCP2020: Pharmacopoeia of the People's Republic of China 2020 edi.
C1)The Encyclopedia of Wakan-Yaku with Color Pictures Vol. I, pp 78-81.
RemarksThe Pharmacopoeia of the People's Republic of China 2020 edition defines the roots of Stephania tetrandra as "Fangji". Its 2000 edition defines that of Aristolochia fangji as "Guangfangji". "Guangfangji" (Radix Aristolochiae Fangchi, Southern Fangchi Root ) is used for expelling wind to relieve pain, reducing fever and inducing diuresis. It is used for damp-heat with pain in the entire body, edema in the lower limb and difficulty in micturition. "Fangji" has the advantage of inducing diuresis and "Guangfangji" has the advantage of expelling wind. "Hanzhongfangji" is said to be derived from the root of Aristolochia heterophylla. The plants of Aristolochia spp. of family Aristolochiaceae contain aristolochic acid which is known to cause renal damage.
In Japan, "Fangji" is called Boi or, sometimes, Boki.
Last renewal date2021/09/27