Crude drug sample data base
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Crude drug name | Market name | アカメガシワ |
|---|---|---|
| Formal name | 赤芽柏 | |
| Japanese name | あかめがしわ, Akamegashiwa | |
| Vernacular name | Akamegashiwa | |
| Latin name | Malloti Cortex (JP) | |
| English name | Mallotus Bark (JP) | |
| Original plant name | Mallotus japonicus Muell.- Arg., (Akamegashiwa) | |
| Family name | Euphorbiaceae | |
| Used part | Classification | Plant origin | Sub classification | bark |
| Collection information | Japan, Osaka Pref. , Tochimoto Tenkaido Co., Ltd. | |
| Collection date | 2007/5/15 | |
| Collector | Katsuko Komatsu | |
| TMPW No. | 25363 | |
The capital city, provincial capital city or the representative
location of its administrative area is indicated.
location of its administrative area is indicated.
Production area information
https://ethmed.toyama-wakan.net/img/pin_san.png
34.6937378
135.50216509999996
Collection information
Japan,Osaka Pref.
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Scientific information data base
| Common name | アカメガシワ（赤芽柏，将軍木皮）, Akamegashiwa, Malloti Cortex (JP18), Mallotus Bark (JP18) | |||
|---|---|---|---|---|
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| Original plant name | Mallotus japonicus Mueller Argoviensis, (Akamegashiwa) | |||
| original plant image |
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| Family name | Euphorbiaceae | |||
| Used part | bark | |||
| Official compendium | JP XVIII | |||
| Clinical application | As an antiulcer drug, Malloti Cortex is applied for gastric ulcer, duodenal ulcer, gastrointestinal disease and cholelithiasis. | |||
| Medical system | Folk medicine | |||
| Chemical constituent | Cardiac glycosides (*C1): [種子/seed] Corotoxigenin, Mallogenin, Coroglaucigenin, Panogeninの3-O-alpha-L-Rhamnopyranosideと3-O-beta-D-Glucopyranosyl-(1→4)-alpha-L-Rhamnopyranoside, Corotoxigenin beta-D-glucopyranosyl-(1→6)-beta-D-glucopyranosyl-(1→4)-alpha-L-rhamnopyranoside Flavones & Flavonols (*C1): [樹皮/bark] Rutin Tannins (*C1): [葉/leaf] Geraniin, Mallotusinic acid, Mallotinic acid Other aromatic derivatives (*C1): [樹皮/bark] Bergenin (*C2,C3): [果皮/pericarp] Butyrylmallotochromene, Isobutyrylmallotochromene, Isomallotochromanol, Isomallotolerin | |||
| Chemical structure |      
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| Pharmacological effect | Bile excretion（water extract of bark：suppression，water extract of leaves：stimulation in small doses，suppression at large doses）．Suppression in gastric juices secretion（bergenin）． | |||
| DNA sequence | AJ275677, AJ275678 | |||
| Disease | Gastric ulcer, Duodenal ulcer, Dyskinesia of the colon, Cholelithiasis, Acid indigestion | |||
| Formulation | ||||
| Related drugs | Kamara (see Remarks) | |||
| References | JP18: The 18th edition of the Japanese Pharmacopoeia. C1)The Encyclopedia of Wakan-Yaku with Color Pictures Vol. II, pp 150-153. C2)J.Nat.Prod.,51,708(1988). C3)Chem.Pharm.Bull.,38,698(1990). | |||
| Remarks | The leaves of Akamegashiwa are applied externally for swelling. The hair and cilia of the fruit of Mallotus philippinensis Muell.-Arg., congener of Akamegashiwa, are called Kamara. It is used as teniacide. | |||
| Last renewal date | 2023/11/30 | |||
