Crude drug sample data base

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Crude drug name

Market nameケンゴシ
Formal name牽牛子
Japanese nameけんごし, Kengoshi
Latin namePharbitidis Semen (JP), (CP)
English namePharbitis Seed (JP), (CP)
Original plant namePharbitis nil Choisy1 or Pharbitis purpurea (L.) Voigt2, (Asagao1, Marubaasagao2)
Family nameConvolvulaceae
Used partClassificationPlant origin
Sub classification seed
Collection informationJapan, Osaka Pref., Tochimoto Tenkaido Co., Ltd.
Collection date2007/5/15
CollectorKatsuko Komatsu
TMPW No.25419

The capital city, provincial capital city or the representative　　
location of its administrative area is indicated.　　
Production area information
https://ethmed.toyama-wakan.net/img/pin_san.png
34.6937378
135.50216509999996
Collection information
Japan,Osaka Pref.
https://ethmed.toyama-wakan.net/img/pin_nyu.png

Scientific information data base

Common name牽牛子, Qianniuzi, Pharbitidis Semen (JP18, CP2020), Pharbitis Seed (JP18, CP2020)
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Original plant namePharbitis nil Choisy1 or Pharbitis purpurea (L.) Voigt2, (Asagao1, Marubaasagao2)
original plant image
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Family nameConvolvulaceae
Used partmature seed
Quality for selectionThe size of good Qianniuzi is large. It sinks under water. (TN)
Official compendiumJP XVIII, CP (2020 ed.)
Clinical applicationAs a mild laxative, laxative and diuretic, Qianniuzi is applied for ascites, constipation and oliguria, retention or stagnation of undigested food. It has anthelmintic action. Contraindicated for pregnant women and dyspeptic person.
Medical systemTraditional Chinese medicine
Drug effect in
traditional medicine		Traditional
classification		Purgatives for removing water retention
Beneficial effect[Property and Flavor] Cold; bitter; toxic.
[Meridian Tropism] Lung, kidney and large intestine meridians.
[Actions] To purge water to relax the bowels, phlegm and flush away fluid retention, kill worms, remove accumulation.
[Indications] Edema distention and fullness, constipation and annuria, phlegm-fluid retention, aggregation and accumulation, panting and cough caused by qi countflow, abdominal pain caused by worm accumulation.
Chemical constituentOther aliphatic and related compounds
(*C1):
Pharbitin 約/about 2% [pharbitic acid (ipurolic acid + glucose, rhamnose, quinovose) の糖部にtiglic adid, d-methyl-ethyl acetic acid, nilic acidが結合したもの]

Plant hormones
(*C1):
Gibberellin (A3, A8, A26, A27, A29) およびそのglucoside（未熟種子/immature seed）
脂肪油約/fatty oil about 11%

Chemical structure


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Pharmacological effectCathartic, activating renal function.
DNA sequenceAF110949, U38310, AF110947, AF110948
Classical reference
(Chinese Herbal Classic "Zhenglei bencao")		※Click this image to see the actual image
DiseaseEdema, Ascites, Oliguria, Constipation, Abdominal pain, Cough, Roundworm
FormulationKufugedokusan, Hachimisenkiho
ReferencesJP18: The 18th edition of the Japanese Pharmacopoeia.
CP2020: Pharmacopoeia of the People's Republic of China 2020 edi.
C1) The Encyclopedia of Wakan-Yaku with Color Pictures Vol. I, pp 302-304.
RemarksThere are two kinds of Qianniuzi depending on the seed coat color. One is black and the other is white. The black one is more common than the white one for medicinal use, since it has a stronger effect.
The Japanese Pharmacopoeia defines Pharbitis nil (Jap. name: Asagao) only. 0.1g at a time is taken, 1 to 3 times a day as a laxative. If the dosage is increased, it is used as a drastic aperient.
Sometimes, the two original plants are included among genus Ipomoea and listed as Ipomoea nil (L.) Roth and I. purpurea (L.) Roth.
Last renewal date2023/02/28
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