Crude drug sample data base

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Crude drug name

Market name栝楼根
Formal name栝楼根
Japanese nameかろこん, Karokon
Vernacular nameGualougen
Latin nameTrichosanthis Radix (JP), (CP)
English nameTrichosanthes Root (JP), Snakegourd Root (CP)
Original plant nameTrichosanthes kirilowii Maxim1, Trichosanthes kirilowii var. japonicum Kitamura2, (Shinakarasuuri1, Kikarasuuri2)
Family nameCucurbitaceae
Used partClassificationPlant origin
Sub classification root
Production area informationPeople's Republic of China, Hebei Prov.
Collection informationJapan, Osaka Pref., Tochimoto Tenkaido Co., Ltd.
Collection date2008/9/27
CollectorKatsuko Komatsu
TMPW No.25881

The capital city, provincial capital city or the representative　　
location of its administrative area is indicated.　　
38.042805
114.51489300000003
Production area information
People's Republic of China,Hebei Prov.
https://ethmed.toyama-wakan.net/img/pin_san.png
34.6937378
135.50216509999996
Collection information
Japan,Osaka Pref.
https://ethmed.toyama-wakan.net/img/pin_nyu.png

Scientific information data base

Common name栝楼根, Gualougen, Trichosanthis Radix (JP18, CP2020), Trichosanthes Root (JP18), Snakegourd Root (CP2020)
Synonyms天花粉 (Tianhuafen)
crude drug image
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Original plant nameTrichosanthes kirilowii Maxim, Trichosanthes kirilowii var. japonicum Kitamura1, Trichosanthes bracteata Voigt2, (Kikarasuuri1, Ōkarasuuri2)
original plant image
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Family nameCucurbitaceae
Used partroot without periderm
Quality for selectionGood guaougen is dense. The cross section is white and has floral patterns in the center. (TN)
Official compendiumJP XVIII, CP (2020 ed.)
Clinical applicationAs an antifebrile, antitussive, diuretic, relactagogue, relieving thirst and for draining pus, it is applied to cure thirst of deficiency syndrome, pain due to pharyngeal swelling, respiratory disease, malignant tumor and all. The powder of "gualougen" ("tenkafun" in JP) is used externaly to infantile skin diseases.
Medical systemTraditional Chinese medicine
Drug effect in
traditional medicine		Traditional
classification		Drugs for reducing intense internal heat
Beneficial effect[Property and Flavor] Mild cold; sweet and mild bitter.
[Meridian Tropism] Lung and stomach meridians.
[Actions] To clear heat, purge fire, engender fluids, quench thirst, disperse swelling and expel pus.
[Indications] Vexation and thirst caused by heat disease, lung heat and dryness cough, interior heat, wasting-thirst, sore and ulcer, swelling skin infections.
Chemical constituentFatty acids
(*C1):
Trichosantic acid

Polysaccharides
(*C1):
澱粉/starch

Triterpenoids
(*C1):
11-Oxo-cucurbit-5-ene-3beta,24,25-triol

Sterols
(*C1):
Stigmasterol, beta-Sitosterol

Amino acids
(*C1):
Citrulline

Simple nitrogen containing compounds
(*C1):
gamma-Aminobutyric acid
(*C2):
Trichosanthin

Chemical structure

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Pharmacological effectHyperglycemia (decoction, water extract)
DNA sequence Traditioal Medical & Parmaceutical Database.
Classical reference
(Chinese Herbal Classic "Zhenglei bencao")		※Click this image to see the actual image
DiseaseThirst, Dry cough, Hemoptysis, Pyogenic dermatosis
FormulationEkigento, Karokeishito, Kangento, Saikokyohangekakaroto, Saikokeishikankyoto, Saikoseikansan, Saikoyoeito, Seishinto, Seisoyoeito, Haiyoto, Bakumondoinshi
Related drugsGualouren (Trichosanthes Semen)
ReferencesJP18: The 18th edition of the Japanese Pharmacopoeia.
CP2020: Pharmacopoeia of the People's Republic of China 2020 edi.
C1) The Encyclopedia of Wakan-Yaku with Color Pictures Vol. I, pp 32-33.
C2) Outline of Pharmacognosy, a Textbook, p 265.
RemarksIn china, "Gualougen" is also called "Tianhuafen". The root of T. rosthornii Herms is used as Chinese "Tianhuafen" as well. "Tenkafun", Japanese pronunciation of "Tianhuafen", is the starch "Gualougen" which is applied externaly on eczema, irritated skin, etc. The root of T. bracteaata Voigt ("Ōkarasuuri" in JP) is also used as Japanese "Gualougen".
Last renewal date2022/11/14
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