Crude drug sample data base
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Production area information
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34.6937378
135.50216509999996
Collection information
Japan,Osaka Pref.
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Scientific information data base
Common name | 沈香, Chenxiang, Aquilariae Resinatum Lignum (Non-JPS2022), Aquilariae Lignum Resinatum (CP2020), Agarwood (Non-JPS2022), Chinese Eaglewood Wood (CP2020) | ||||||
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Original plant name | Aquilaria agallocha Roxburgh, Aquilaria crassna Pierre ex Lecomte, Aquilaria malaccensis Lamarck, Aquilaria sinensis Gilg or Aquilaria filaria Merrill | ||||||
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Family name | Thymelaeaceae | ||||||
Used part | wood, especially splint wood containing penetrated black resin | ||||||
Quality for selection | It should be firm, blackish in color, glossy on the surface, submerged in water, easy to burn and fragrant. (TN) | ||||||
Official compendium | Non-JPS (2022), CP (2020 ed.) | ||||||
Clinical application | As an antivomiting, antitussive, and sedative, it is applied to treat hysteria, qi stagnation, vomiting, asthma, and cardiac weakness. It is generally used as a fragrance material for high-grade incense sticks and combined incense. | ||||||
Medical system | Traditional Chinese medicine | ||||||
Drug effect in traditional medicine | Traditional classification | Carminatives for regulating flow of Qi | |||||
Beneficial effect | [Property and Flavor] Mild warm; pungent and bitter. [Meridian Tropism] Spleen, stomach and kidney meridians. [Actions] To move qi and relieve pain, warm the middle energizer to check vomiting, absorb qi to relieve panting. [Indications] Distention, oppression and pain in the chest and the abdomen, vomiting and hiccup caused by stomach cold, panting caused by qi counterflow caused by kidney deficiency. | ||||||
Chemical constituent | Sesquiterpenoids (*C1): Agarospiol, Agarol, Agarofurans (*C2-7): alpha-Agarofuran, (-)-10-Epi-gamma-eudesmol, Jinkoh-eremol, Kusunol, Jinkohol, JinkoholⅡ, Dihydrokaranone, Agarospirol, Oxo-agarospirol Phenylpropanoids (*C1): Hydrocinnamic acid, p-Methoxyhydrocinnamic acid gamma-Pyrone derivatives (*C1): Agaroterol Other aromatic derivatives (*C1): Benzylacetone, p-Methoxybenzylacetone | ||||||
Chemical structure |
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Pharmacological effect | Analgesia, sedation (essential oil), antibacterial (decoction: Mycobacterium tuberculosis, Salmonella typhi, Shigella). | ||||||
DNA sequence | Y15149 | ||||||
Classical reference (Chinese Herbal Classic "Zhenglei bencao") | ※Click this image to see the actual image | ||||||
Disease | Pain due to flatulence of hypochondrium, Feeling of pressure in the chest, Chest pain, Vomitting, Hiccup, Dyspnea, Rapid breathing, Hysteria | ||||||
Formulation | Kagenshosaikoto, Jinkokokito, Zenshikunshito, Daibyakuchuin, Chokoshiteito, Tokiyoketsuto, Hojinto | ||||||
Related drugs | Jiananxian (Jialu) | ||||||
References | Non-JPS2022: The Japanese standards for non-Pharmacopoeial crude drugs 2022. CP2020: Pharmacopoeia of the People's Republic of China 2020 edi. C1)The Encyclopedia of Wakan-Yaku with Color Pictures Vol. II, pp 181-184. C2-7)Shoyakugaku Zasshi,40(3), 252, 259, 266, 271, 275(1986); 41(2), 142(1987). C8)Shosoin Medicaments, pp132-135, 147-148. | ||||||
Remarks | - The original plant of Chenxiang includes Aquilaria agallocha Roxb. (products of India, Malaysia, Vietnam and Cambodia), A. malaccensis Lam. (Malaysia), A. baillonii Pierre (Cambodia), A. crassna Pierre (Cambodia and Vietnam) and A. sinensis (Lour.) Gilg (China). Japan imports a large amount from Singapore and Vietnam. They are identified by the composition of sesquiterpenoids as follows.: Singapore I-type (SI-type) contains much jinkohol and jinkohol II. SingaporeII-type (SII-type) does not contain them. Vietnam type (V-type) does not contain jinkohol nor jinkohol II but much dihydrokaranone and oxo-agarospirol (C2, C5). Chinese Chenxiang resembles V-type, which has a high content of oxo-agarospirol (C3). The allied species Kanankō (伽南香, Jap. name), which is also called Kyara (伽羅), has been said to be superior to Chenxiang. It contains chromones which are not found in Chenxiang. In addition, it has higher contents of benzene extract (C5) and acetone extract (C7). - A. sinensis produced in China is listed in the Chinese Pharmacopoeia (2020) and is called Dojinkō, Kainanjinkō and etc. It is mostly imported into Japan for use as incense. - The medicines stored in the Shosoin Repository include Jinkō and Zōjin, Zensenkō (Kōjin), and Ōjukukō (Ranjatai). They have no sesquiterpenoids nor 1-8diethylchromone nor phenyethylchromone. Therefore, it is attested that their origins are closely related to Chenxiang produced in northern Indochina such as Vietnam (C8). Thus, in the middle of the 8th century, items similar to those on the market today were introduced to Japan. | ||||||
Last renewal date | 2022/07/20 | ||||||