Crude drug sample data base

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Crude drug name

Market nameアカメガシワ
Formal name赤芽柏
Japanese nameあかめがしわ, Akamegashiwa
Vernacular nameAkamegashiwa
Latin nameMalloti Cortex (JP)
English nameMallotus Bark (JP)
Original plant nameMallotus japonicusMuell.- Arg., (Akamegashiwa)
Family nameEuphorbiaceae
Used partClassificationPlant origin
Sub classification bark
Collection informationJapan, Tokyo, Uchida Wakanyaku Co., Ltd.
Collection date2011/11/15
CollectorHirotoshi Fushimi
TMPW No.27501

The capital city, provincial capital city or the representative　　
location of its administrative area is indicated.　　
Production area information
https://ethmed.toyama-wakan.net/img/pin_san.png
35.6894875
139.69170639999993
Collection information
Japan,Tokyo
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Scientific information data base

Common nameアカメガシワ（赤芽柏，将軍木皮）, Akamegashiwa, Malloti Cortex (JP18), Mallotus Bark (JP18)
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Original plant nameMallotus japonicus Mueller Argoviensis, (Akamegashiwa)
original plant image
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Family nameEuphorbiaceae
Used partbark
Official compendiumJP XVIII
Clinical applicationAs an antiulcer drug, Malloti Cortex is applied for gastric ulcer, duodenal ulcer, gastrointestinal disease and cholelithiasis.
Medical systemFolk medicine
Chemical constituentCardiac glycosides
(*C1):
[種子/seed] Corotoxigenin, Mallogenin, Coroglaucigenin, Panogeninの3-O-alpha-L-Rhamnopyranosideと3-O-beta-D-Glucopyranosyl-(1→4)-alpha-L-Rhamnopyranoside, Corotoxigenin beta-D-glucopyranosyl-(1→6)-beta-D-glucopyranosyl-(1→4)-alpha-L-rhamnopyranoside

Flavones & Flavonols
(*C1):
[樹皮/bark] Rutin

Tannins
(*C1):
[葉/leaf] Geraniin, Mallotusinic acid, Mallotinic acid

Other aromatic derivatives
(*C1):
[樹皮/bark] Bergenin
(*C2,C3):
[果皮/pericarp] Butyrylmallotochromene, Isobutyrylmallotochromene, Isomallotochromanol, Isomallotolerin

Chemical structure






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Pharmacological effectBile excretion（water extract of bark：suppression，water extract of leaves：stimulation in small doses，suppression at large doses）．Suppression in gastric juices secretion（bergenin）．
DNA sequenceAJ275677, AJ275678
DiseaseGastric ulcer, Duodenal ulcer, Dyskinesia of the colon, Cholelithiasis, Acid indigestion
Formulation
Related drugsKamara (see Remarks)
ReferencesJP18: The 18th edition of the Japanese Pharmacopoeia.
C1)The Encyclopedia of Wakan-Yaku with Color Pictures Vol. II, pp 150-153.
C2)J.Nat.Prod.,51,708(1988).
C3)Chem.Pharm.Bull.,38,698(1990).
RemarksThe leaves of Akamegashiwa are applied externally for swelling. The hair and cilia of the fruit of Mallotus philippinensis Muell.-Arg., congener of Akamegashiwa, are called Kamara. It is used as teniacide.
Last renewal date2023/11/30
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