Crude drug sample data base

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Crude drug name

Market nameアカメガシワ
Formal name赤芽柏
Japanese nameあかめがしわ, Akamegashiwa
Vernacular nameAkamegashiwa
Latin nameMalloti Cortex (JP)
English nameMallotus Bark (JP)
Original plant nameMallotus japonicusMuell.- Arg., (Akamegashiwa)
Family nameEuphorbiaceae
Used partClassificationPlant origin
Sub classification bark
Collection informationJapan, Tokyo, Uchida Wakanyaku Co., Ltd.
Collection date2011/11/15
CollectorHirotoshi Fushimi
TMPW No.27501

The capital city, provincial capital city or the representative　　
location of its administrative area is indicated.　　
Production area information
https://ethmed.toyama-wakan.net/img/pin_san.png
35.6894875
139.69170639999993
Collection information
Japan,Tokyo
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Scientific information data base

Common nameアカメガシワ（赤芽柏，将軍木皮）, Akamegashiwa, Malloti Cortex (JP), Mallotus Bark (JP)
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Original plant nameMallotus japonicus Mueller Argoviensis, (Akamegashiwa)
original plant image
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Family nameEuphorbiaceae
Used partbark
Official compendiumJP XIX
Clinical applicationIt is used as an antiulcer agent for gastric ulcer, duodenal ulcer, gastrointestinal disorders, cholelithiasis, and related conditions.
Medical systemFolk medicine
Chemical constituentCardiac glycosides
(*C1):
[種子/seed] Corotoxigenin, Mallogenin, Coroglaucigenin, Panogeninの3-O-alpha-L-Rhamnopyranosideと3-O-beta-D-Glucopyranosyl-(1→4)-alpha-L-Rhamnopyranoside, Corotoxigenin beta-D-glucopyranosyl-(1→6)-beta-D-glucopyranosyl-(1→4)-alpha-L-rhamnopyranoside

Flavones & Flavonols
(*C1):
[樹皮/bark] Rutin

Tannins
(*C1):
[葉/leaf] Geraniin, Mallotusinic acid, Mallotinic acid

Other aromatic derivatives
(*C1):
[樹皮/bark] Bergenin
(*C2,C3):
[果皮/pericarp] Butyrylmallotochromene, Isobutyrylmallotochromene, Isomallotochromanol, Isomallotolerin

Chemical structure






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Pharmacological effectBile excretion（water extract of bark：suppression，water extract of leaves：stimulation in small doses，suppression at large doses）．Suppression in gastric juices secretion（bergenin）．
DNA sequenceAJ275677, AJ275678
DiseaseGastric ulcer, Duodenal ulcer, Dyskinesia of the colon, Cholelithiasis, Acid indigestion
Formulation
Related drugsKamara (see Remarks)
ReferencesJP19: The 19th edition of the Japanese Pharmacopoeia.
C1)The Encyclopedia of Wakan-Yaku with Color Pictures Vol. II, pp 150-153.
C2)J.Nat.Prod.,51,708(1988).
C3)Chem.Pharm.Bull.,38,698(1990).
RemarksThe leaves of Akamegashiwa are applied externally for for boils and swellings. The hairs and glandular hairs on the surface of the fruits of Mallotus philippinensis Muell.-Arg., which belongs to the same genus as Akamegashiwa, are called Kamala and are used as a taeniacide.
Last renewal date2026/05/12
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