Crude drug sample data base

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Crude drug name

Market name甘遂
Formal name甘遂
Japanese nameかんつい, Kantsui
Vernacular nameGansui
Latin nameKansui Radix (CP)
English nameGansui Root (CP)
Original plant nameEuphorbia kansui Liou
Family nameEuphorbiaceae
Used partClassificationPlant origin
Sub classification root
Collection informationHong Kong, Wing Tai Hong Medicine Co.,Ltd.
Collection date1974/12/25
TMPW No.278

Scientific information data base

Common name甘遂, Gansui, Kansui Radix (CP2020), Gansui Root (CP2020)
crude drug image
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Original plant nameEuphorbia kansui T.N.Liou. ex T.P.Wan
Family nameEuphorbiaceae
Used partroot
Quality for selectionGood Gansui is about the size of a head of finger. The outside has red spots. The inside is stiff and white. The radixes look like strings of beads. (NI)
Official compendiumCP (2020 ed.)
Clinical applicationAs a diuretic and drastic purgation, Gansui is applied for edema, abdominal distention and chest pain. It is also used for ascites due to pleurisy and later stage of schistosomiasis japonica. In Chinese traditional medicine, it is said to be a sacred medicine for purging away retained fluid, as well as daji. Gansui is contraindicated for person with delicate constitution and pregnant women.
Medical systemTraditional Chinese medicine
Drug effect in
traditional medicine
Purgatives for removing water retention
Beneficial effect[Property and Flavor] Cold; bitter; toxic.
[Meridian Tropism] Lung, kidney and large intestine meridians.
[Actions] To expel retained fluid by purgation, disperse swelling and dissipate binds.
[Indications] Edema distention and fullness, hydrothorax and ascites, phlegm-fluid retention aggregation and accumulation, panting and cough caused by qi counterflow, inhibited of defecation and urination, wind-phlegm epilepsy, swelling abscess, sore and toxin.
Chemical constituentDiterpenoids
13-Hydroxyingenol-3-(2,3-dimethylbutanoate)-13-dodecanoate-20-hexadecanoate (= Kansuiphorin A), 6,7-Epoxy-13-hydroxyingenol-3-(2,3-dimethylbutanoate)-13-dodecanoate-20-hexadecanoate (= Kansuiphorin B)
Kansuinine A, Kansuinine B

Tirucallol (= Kanzuiol), Euphol, Euphorbol

Chemical structure

Pharmacological effectCathartic (alcohol extract). Analgesia (kansuinine A). The raw Gansui Root is highly toxic.
Classical reference
(Chinese Herbal Classic "Zhenglei bencao")
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DiseaseAscites, Edema, Thirst, Oliguria, Constipation, Pleural effusion, Feeling of pressure in the chest, Dyspnea, Epilepsy, Pyogenic dermatosis
ReferencesCP2020: Pharmacopoeia of the People's Republic of China 2020 edi.
C1)Tetrahedron Lett., 29, 2529-2532(1974).
C2)J. Nat. Prod., 54, 823-829(1991).
C3)Tetrahedron Lett., 21, 1697-1705(1975)
C4)The Encyclopedia of Wakan-Yaku with Color Pictures Vol. I, pp 53-54.
RemarksIt is listed in Shen Nong Ben Cao Jing, which classifies it as a low grade drug.
Last renewal date2021/09/27