Crude drug sample data base
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Crude drug name | Market name | 甘遂 |
|---|---|---|
| Formal name | 甘遂 | |
| Japanese name | かんつい, Kantsui | |
| Vernacular name | Gansui | |
| Latin name | Kansui Radix (CP) | |
| English name | Gansui Root (CP) | |
| Original plant name | Euphorbia kansui Liou | |
| Family name | Euphorbiaceae | |
| Used part | Classification | Plant origin | Sub classification | root |
| Collection information | Hong Kong, Wing Tai Hong Medicine Co.,Ltd. | |
| Collection date | 1974/12/25 | |
| TMPW No. | 279 | |
Scientific information data base
| Common name | 甘遂, Gansui, Kansui Radix (CP2020), Gansui Root (CP2020) | ||||
|---|---|---|---|---|---|
| crude drug image |
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| Original plant name | Euphorbia kansui T.N.Liou. ex T.P.Wan | ||||
| Family name | Euphorbiaceae | ||||
| Used part | root | ||||
| Quality for selection | Good Gansui is about the size of a head of finger. The outside has red spots. The inside is stiff and white. The radixes look like strings of beads. (NI) | ||||
| Official compendium | CP (2020 ed.) | ||||
| Clinical application | As a diuretic and drastic purgation, Gansui is applied for edema, abdominal distention and chest pain. It is also used for ascites due to pleurisy and later stage of schistosomiasis japonica. In Chinese traditional medicine, it is said to be a sacred medicine for purging away retained fluid, as well as daji. Gansui is contraindicated for person with delicate constitution and pregnant women. | ||||
| Medical system | Traditional Chinese medicine | ||||
| Drug effect in traditional medicine | Traditional classification | Purgatives for removing water retention | |||
| Beneficial effect | [Property and Flavor] Cold; bitter; toxic. [Meridian Tropism] Lung, kidney and large intestine meridians. [Actions] To expel retained fluid by purgation, disperse swelling and dissipate binds. [Indications] Edema distention and fullness, hydrothorax and ascites, phlegm-fluid retention aggregation and accumulation, panting and cough caused by qi counterflow, inhibited of defecation and urination, wind-phlegm epilepsy, swelling abscess, sore and toxin. | ||||
| Chemical constituent | Diterpenoids (*C1): 13-Hydroxyingenol (*C2): 13-Hydroxyingenol-3-(2,3-dimethylbutanoate)-13-dodecanoate-20-hexadecanoate (= Kansuiphorin A), 6,7-Epoxy-13-hydroxyingenol-3-(2,3-dimethylbutanoate)-13-dodecanoate-20-hexadecanoate (= Kansuiphorin B) (*C3): Kansuinine A, Kansuinine B Triterpenoids (*C4): Tirucallol (= Kanzuiol), Euphol, Euphorbol | ||||
| Chemical structure |    
※画像をクリックすると、拡大して表示されます。 | ||||
| Pharmacological effect | Cathartic (alcohol extract). Analgesia (kansuinine A). The raw Gansui Root is highly toxic. | ||||
| Classical reference (Chinese Herbal Classic "Zhenglei bencao") |  ※Click this image to see the actual image | ||||
| Disease | Ascites, Edema, Thirst, Oliguria, Constipation, Pleural effusion, Feeling of pressure in the chest, Dyspnea, Epilepsy, Pyogenic dermatosis | ||||
| Formulation | Kanzuihangeto | ||||
| References | CP2020: Pharmacopoeia of the People's Republic of China 2020 edi. C1)Tetrahedron Lett., 29, 2529-2532(1974). C2)J. Nat. Prod., 54, 823-829(1991). C3)Tetrahedron Lett., 21, 1697-1705(1975) C4)The Encyclopedia of Wakan-Yaku with Color Pictures Vol. I, pp 53-54. | ||||
| Remarks | It is listed in Shen Nong Ben Cao Jing, which classifies it as a low grade drug. | ||||
| Last renewal date | 2021/09/27 | ||||
