Crude drug sample data base
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Crude drug name | Market name | 山豆根 |
|---|---|---|
| Formal name | 山豆根 | |
| Japanese name | さんずこん, Sanzukon | |
| Vernacular name | Shandougen | |
| Latin name | Sophorae Subprostratae Radix (Non-JPS), Sophorae Tonkinensis Radix et Rhizoma (CP) | |
| English name | Sophora Subprostrata Root (Non-JPS), Vietnamese Sophora Root (CP) | |
| Original plant name | Sophora subprostrata Chun et T. Chen | |
| Family name | Leguminosae | |
| Used part | Classification | Plant origin | Sub classification | root |
| Collection information | People's Republic of China, Kunming | |
| Collection date | 1980/06/21 | |
| TMPW No. | 280 | |
The capital city, provincial capital city or the representative
location of its administrative area is indicated.
location of its administrative area is indicated.
Production area information
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24.880095
102.83289100000002
Collection information
People's Republic of China,Kunming
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Scientific information data base
| Common name | 山豆根, Shandougen, Sophorae Subprostratae RadixNon-JPS, Sophorae Tonkinensis Radix et RhizomaCP, Sophora Subprostrata RootNon-JPS, Vietnamese Sophora RootCP | |||||
|---|---|---|---|---|---|---|
| Synonyms | 広豆根 | |||||
| crude drug image |
| |||||
| Original plant name | Sophora subprostrata Chun et T. Chen (= Sophora tonkinensis Gagnep.) | |||||
| Family name | Leguminosae | |||||
| Used part | root and rhizome | |||||
| Official compendium | Non-JPS (2022), CP (2025 ed.) | |||||
| Clinical application | It is used as a detoxifying, analgesic, anti-inflammatory, and antitumor agent for conditions such as sore throat with swelling and the early stages of lung and pharyngeal cancers. It is applied externally for cervicitis and stomatitis. | |||||
| Medical system | Traditional Chinese medicine | |||||
| Drug effect in traditional medicine | Traditional classification | Febrifugal and detoxicant drugs | ||||
| Beneficial effect | [Property and Flavor] Cold; bitter; toxic. [Meridian Tropism] Lung and stomach. [Actions] To clear heat, remove toxin, disperse swelling and soothe the throat. [Indications] Retained fire toxin bind, tonsillitis and throat impediment, swelling and sore throat and gum, mouth and tongue sores. | |||||
| Chemical constituent | Triterpenoid saponins (*C1): Lupeol Sterols (*C1): beta-Sitosterol Isoflavones (*C1): l-Maackiain, Trifolirhizin, l-Pterocarpin, Genistein Chalcones, Dihydrochalcones & Aurones (*C1): Sophoradin, Sophoranone, Sophoradochromene, Sophoranochromene Phenol derivatives (*C1): trans-Caffeic acid docosylesterを主にした新phenol性物質/ A novel phenolic compound consisting primarily of trans-caffeic acid docosyl ester. Quinolizidine alkaloids (*C1): Matrine, Oxymatrine, Anagyrine, N-Methylcytisine Isoquinoline alkaloids Menispermum dauricum (*C2): Dauricoside | |||||
| Chemical structure |    
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| Pharmacological effect | Antitumor activity and inhibitory effects on stress-induced ulcers (extract); antitumor activity (matrine); inhibitory effects on pylorus ligation-induced and stress-induced ulcers, and suppression of gastric juice secretion (sophoradin, sophoranone). | |||||
| DNA sequence | AF142693, AF309829, AF311369, AF309828, AF123452, AF142693, AF174638; Traditioal Medical & Parmaceutical Database. | |||||
| Classical reference (Chinese Herbal Classic "Zhenglei bencao") |  ※Click this image to see the actual image | |||||
| Disease | Swelling and pain of the throat, Swelling and pain of the root of tooth, Early cancer, Skin ulcer, Cervicitis, Stomatitis | |||||
| Formulation | rarely used in formula | |||||
| Related drugs | Beidougen (see "Remarks") | |||||
| References | Non-JPS: The Japanese standards for non-Pharmacopoeial crude drugs 2022. CP: Pharmacopoeia of the People's Republic of China 2025 edi. C1) The Encyclopedia of Wakan-Yaku with Color Pictures Vol. I, pp 10-12. C2) Chem.Pharm.Bull.,41,1866-1868(1993). [PMID: 8281582] | |||||
| Remarks | "Shandougen" has several kinds of origin. For the present, the "Shandougen", imported from China, belongs to genus Sophora. It is produced in Guangxi Zhuang Autonomous Region. "Shandougen" of Northeast and North China called "Beidougen", is the rhizome of Menispermum dauricum DC. of family Menispermaceae (Jap. Name: "Komorikazura"). In Hubei, Henan, Shanxi, Gansu, Shanxi, Jiangsu and others, "Shandougen" is the root of many kinds of genus Indigofera, family Leguminosae, such as Indigofera amblyantha Craib, I. fortunei Craib and I. ichangensis Craib. | |||||
| Last renewal date | 2026/10/09 | |||||
