Crude drug sample data base

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Crude drug name

Market name骨膠
Formal name阿膠
Japanese nameあきょう, Akyō
Vernacular nameEjiao
Latin nameAsini Corii Collas (JP)
English nameDonkey Glue (JP), Ass-hide Glue, Donkey-hide Glue
Original plant nameBos taurus L. var. domesticus Gmelin, (Ushi)
Family nameBovidae
Used partClassificationAnimal origin
Sub classification the dry concentrated heat-extract prepared by boiling the hairless hide, bone, tendon and ligament of mammals with water and excluding fat
TMPW No.2890

Scientific information data base

Common name阿膠, Ejiao, Asini Corii Collas (Non-JPS2022), Asini Corii Colla (CP2020), Donkey Glue (Non-JPS2022), Donkey-hide Glue (CP2020)
Synonyms山東阿膠, 玉阿膠
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Original plant nameEquus asinus Linn.1<ウマ科/Equidae>, Equus caballus×Equus asinus2<ウマ科/Equidae>, Bos taurus Linn. var. domesticus Gmelin3<ウシ科/Bovidae>, (Roba1, Raba2, Ushi3)
Used parthide glue
Quality for selectionGood Ejiao is clear yellow like amber or transparent dark-red. It should not get soft even in summer. (NI)
Official compendiumNon-JPS (2022), CP (2020 ed.)
Clinical applicationTo enrich the blood and stop bleeding, Ejiao is applied for bleeding, hematemesis, hemoptysis and cough.
Medical systemTraditional Chinese medicine
Drug effect in
traditional medicine
Traditional
classification
Drugs for nourishing the blood
Beneficial effect[Property and Flavor] Neutral; sweet.
[Meridian Tropism] Lung, liver and kidney meridians.
[Actions] To nourish blood, replenish yin, moisten dryness, arid stanch bleeding.
[Indications] Blood deficiericy with sallow complexion, dizziness, palpitations, weak muscle, lack of strength, insomnia caused by vexation, internal stirring of defiency wind, cough caused by lung dryness, cough in consumptive disease, hemoptysis, hematemesis and hematuria, bloody stool, menstrual flooding and spotting, and vaginal bleeding during pregnancy.
Chemical constituentPeptide
(*C1):
Collagen, Glutin

Pharmacological effectEnhancing blood clotting.
DNA sequenceAF221593, AY011180
Classical reference
(Chinese Herbal Classic "Zhenglei bencao")
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DiseaseNasal hemorrhage, Hemoptysis, Hematemesis, Hematuria, Hematochezia, Irregular vaginal bleeding, Hypermenorrhea, Cough, Dry cough, Few sputum, Sputum with blood, Rapid breathing, Thirst, Lightheadedness, Vertigo, Palpitation, Fret, Insomnia, Heat, Twitch of the muscles, Night sweats
FormulationAkyobushito, Unkeito, Odoto, Oren'akyoto, Kyukikyogaito, Kyukihochuto, Kyososan, Shionsan, Shakanzoto, Junhaito, Shokanto, Shokanto, Shogedokuto, Seikanto, Chimobukuryoto, Chushaen, Choreito, Choreitogoshimotsuto, Tojinto, Hakutookakanzoakyoto, Ninjin-yoei-to, Hakutookakanzoakyoto, Yohaito
Related drugsDeer Horn and Pilose Antler (see "Remarks")
ReferencesNon-JPS2022: The Japanese standards for non-Pharmacopoeial crude drugs 2022.
CP2020: Pharmacopoeia of the People's Republic of China 2020 edi.
C1) The Encyclopedia of Wakan-Yaku with Color Pictures Vol. II, pp 320-321.
RemarksSantō Akyō (Jap. name), produced in Shandong Prov., is of fair quality. Japanese Ejiao is made from the skin, bone and tendon of cows, pigs and whales. Though, cow's skin and bone are often used, it is not for medicinal but for industrial use. Therefore, gelatinum is often substituted for Ejiao in Japan.
"Tamaakyō" is the heated and swelled fragments of Ejiao. It is not appropriate to use it as Ejiao since the quality of the original glue is uncertain and it is processed using high temperatures. "Rokkakukyō" and "Rokujōkyō", made from deer horn and pilose antler respectively, are high quality. Their medicinal virtues are slightly different from Ejiao. They are used as medicine for warming the spleen and liver, and strengthening essence and tonifying the blood. They are applied for impotence and spermatorrhea, cold pain of loin and knee, macerating and consumptive disease, metrorrhagia and metrostaxis, melaena, hematochezia and hematuria, cellulitis of Yin and pain of swelling.
Last renewal date2022/07/19