Crude drug sample data base

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Crude drug name

Market nameチモ [NIB-529]
Formal name知母
Japanese nameちも, Chimo
Vernacular nameZhimu
Latin nameAnemarrhenae Rhizoma (JP), (CP)
English nameAnemarrhena Rhizome (JP), Common Anemarrhena Rhizome (CP)
Original plant nameAnemarrhena sp.
Family nameLiliaceae
Used partClassificationPlant origin
Sub classification rhizome
Production area informationPeople's Republic of China, Hebei Prov.
Collection informationJapan, Ibaraki Pref., National Institutes of Biomedical Innovation, Health and Nutrition
Collection date2013/10/22
CollectorKatsuko Komatsu
Remarks [NIB-529]
TMPW No.29515

The capital city, provincial capital city or the representative　　
location of its administrative area is indicated.　　
38.042805
114.51489300000003
Production area information
People's Republic of China,Hebei Prov.
https://ethmed.toyama-wakan.net/img/pin_san.png
36.3418112
140.4467935
Collection information
Japan,Ibaraki Pref.
https://ethmed.toyama-wakan.net/img/pin_nyu.png

Scientific information data base

Common name知母, Zhimu, Anemarrhenae Rhizoma (JP18, CP2020), Anemarrhena Rhizome (JP18), Common Anemarrhena Rhizome (CP2020)
Synonyms毛知母，光知母，知母肉
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Original plant nameAnemarrhena asphodeloides Bunge, (Hanasuge)
original plant image
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Family nameLiliaceae
Used partrhizome
Quality for selectionGood Zhimu is enlarged, moist and has yellow hair roots. (TN)
Official compendiumJP XVIII, CP (2020 ed.)
Clinical applicationAs an antifebrile, diuretic, tranquilizer, antiussive and antidiarrheal drug, zhimu is applied for high fever and excessive thirst.
Medical systemTraditional Chinese medicine
Drug effect in
traditional medicine		Traditional
classification		Drugs for reducing intense internal heat
Beneficial effect[Property and Flavor] Cold; bitter and sweet.
[Meridian Tropism] Lung, stomach and kidney meridians.
[Actions] To clear heat, purge fire, nourish yin to moisten dryness.
[Indications] External contraction of febrile disease, high fever with vexation and thirst, lung heat with dry cough, bone-steaming and tidal fever, interior heat wasting-thirst, constipation caused by intestinal dryness.
Chemical constituentSteroid saponins & Sapogenins
(*C1):
Timosaponin A-I, Timosaponin A-II, Timosaponin A-III, Timosaponin A-IV, Timosaponin B-I, Timosaponin B-II, Sarsasapogenin, Markogenin, Neogitogenin

Xanthones
(*C1):
Mangiferin, Isomangiferin

Amino acids
(*C1):
Pantothenic acid

Pyridine alkaloids
(*C1):
Nicotinic acid

Chemical structure




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Pharmacological effectHypoglycemic （extract）．Antipyretic and antibacterial （decoction）．Hypotensive, suppression of respiratory center, hemolytic （timosaponins)．
DNA sequence Traditioal Medical & Parmaceutical Database.
Classical reference
(Chinese Herbal Classic "Zhenglei bencao")		※Click this image to see the actual image
DiseaseHigh fever, Thirst, Cough, Dry cough, Night sweats, Anhidrosis, Dysuria, Constipation
FormulationIshoho, Ogibekkoto, Orenshodokuin, Kagenshahakusan, Kamishimotsuto, Kamihachimyakusan, Keishishakuyakuchimoto, Saikoyoeito, Sansoninto, Jiinkokato, Jiinshihoto, Shionsan, Jijintsujito, Shofusan, Joshitsuhokito, Shin'iseihaito, Jingyobekkoto, Seishinto, Seisoyoeito, Seinetsuhoketsuto, Chimobukuryoto, Tokinentsuto, Bakumondoinshi, Byakkokakeishito, Byakkokaninjinto, Hointo
ReferencesJP18: The 18th edition of the Japanese Pharmacopoeia.
CP2020: Pharmacopoeia of the People's Republic of China 2020 edi.
C1) The Encyclopedia of Wakan-Yaku with Color Pictures Vol. I, pp 87-89.
RemarksThere are two types in "Zhimu (知母)", "Maozhimu" and "Guangzhimu". "Guangzhimu", in which yellowish brown fine roots of the surface have been removed, is appreciated as high quality in China, but it is not used in Japan. The rhizome of Aspidistra genus of family Liliaceae is a substitute for above in Zhuangzu Autonomous Region of Guangxi Province ("Maozhimu") and Taiwan ("Guangzhimu").
Last renewal date2021/09/27
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