Crude drug sample data base

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Crude drug name

Market nameエンゴサク [NIB-987]
Formal name延胡索
Japanese nameえんごさく, Engosaku
Vernacular nameYanhusuo
Latin nameCorydalis Tuber (JP), Corydalis Rhizoma (CP)
English nameCorydalis Tuber (JP), Yanhusuo (CP)
GradeA
Original plant nameCorydalis sp.
Family namePapaveraceae
Used partClassificationPlant origin
Sub classification tuber
Production area informationPeople's Republic of China, Zhejiang Prov.
Collection informationJapan, Ibaraki Pref., National Institutes of Biomedical Innovation, Health and Nutrition
Collection date2014/6/2
CollectorKatsuko Komatsu
Remarks [NIB-987]
TMPW No.29533

The capital city, provincial capital city or the representative  
location of its administrative area is indicated.  
30.274084
120.15507000000002
Production area information
People's Republic of China,Zhejiang Prov.
https://ethmed.toyama-wakan.net/img/pin_san.png
36.3418112
140.4467935
Collection information
Japan,Ibaraki Pref.
https://ethmed.toyama-wakan.net/img/pin_nyu.png

Scientific information data base

Common name延胡索, Yanhusuo, Corydalis Tuber (JP18), Corydalis Rhizoma (CP2020), Corydalis Tuber (JP18), Yanhusuo (CP2020)
Synonyms元胡, 玄胡索
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Original plant nameCorydalis turtschaninovii Besser forma yanhusuo Y. H. Chou et C. C. Hsu
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Family namePapaveraceae
Used parttuber
Quality for selectionThe grain of good Yanhusuo is round, big and yellow. (TN)
Official compendiumJP XVIII, CP (2020 ed.)
Clinical applicationAs an antispasmodic, painkiller, peptic ulcer, yanhusuo is applied for headache, heartburn, stomachache, abdominal pain and algomenorrhea. Especially good for hypogastric pain due to paramenia. It is also applied to cure gastric and duodenal ulcer.
Medical systemTraditional Chinese medicine
Drug effect in
traditional medicine
Traditional
classification
Drugs for invigorating blood circulation
Beneficial effect[Property and Flavor] Warm; pungent and bitter.
[Meridian Tropism] Liver and spleen.
[Actions] To activate blood, move qi, and relieve pain.
[Indications] Pain in the chest, the hypochondrium, epigastrium and abdomen; chest impediment and heart pain, amenorrhea and dysmenorrhea, postpartum stasis and obstruction, swelling and pain caused by traumatic injuries.
Chemical constituentIsoquinoline alkaloids
Corydalis spp. (*C1):
dl-Tetrahydropalmatine, l-Tetrahydrocoptisine, d-Corydaline, d-Base II, dl-Base II, l-Canadine, l-Tetrahydrocolumbamine, d-Corybulbine, l-Scoulerine, Coptisine, Dehydrocorydaline, Dehydrothalictrifoline, Berberine, Dehydrocorybulbine, Columbamine, d-Glaucine, d-Isocorydine, Columbamine, d-Norisocorydine, Bulbocapnine, Protopine, alpha-Allocryptopine, Ambiguapine
C. decumbens (*C2):
Palmatine, Tetrahydropalmatine, Decumbensine, Protopine, Bulbocapnine, Adlumidine

Chemical structure




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Pharmacological effectAnalgesic (extract), suppression of central nervous system, analgesic (tetrahydropalmatine), suppression of gastric acid release (dehydrocorydaline).
DNA sequenceAF093722,AF094544,U86622; Traditioal Medical & Parmaceutical Database.
Classical reference
(Chinese Herbal Classic "Zhenglei bencao")
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DiseaseMenorrhalgia, Amenorrhea, Hyperemesis after childbirth, Chest pain, Upper abdominal pain, Swelling and pain due to contusion, Lower abdominal pain, Gastric ulcer, Duodenal ulcer
FormulationAnchusan, Ureitsukito, Goshitsusan, Sesshoin, Hachimisenkiho
ReferencesJP18: The 18th edition of the Japanese Pharmacopoeia.
CP2020: Pharmacopoeia of the People's Republic of China 2020 edi.
C1) The Encyclopedia of Wakan-Yaku with Color Pictures Vol.I, pp 83-86.
C2) Shoyakugaku Zasshi,47,440(1993).
RemarksCorydalis turtschaninovii forma yanhusuo is cultivated in Zhejiang Prov. and Jiamgsu Prov. in China. Though, the tuber of this species is the genuine one, C. nakaii Ishidoya (Kōraiengosaku) is produced in Inner Mongolia, the provinces of Northeast Part and the Korean Peninsula.
Last renewal date2021/09/27