Crude drug sample data base
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Crude drug name | Market name | Kuchala |
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Formal name | Karaskara | |
Other names Tips! | Kuchilaa, Nux vomica seed (T), Koonchilaa (B), Kuchilaa (H), Musti bija (K), Kanniram (M), Mustimanu (Te), Ettikottai (Ta), Basa musta (Ti), Kajara, Kucila (N), Godakadur (Sin) | |
English name | Nux Vomica | |
Original plant name | Strychnos nux-vomica Linn., Nux Vomica | |
Family name | Loganiaceae | |
Used part | Classification | Plant origin | Sub classification | seed |
Collection information | India, New Delhi, Hans Raj & Sons | |
Collection date | 1991/05/07 | |
Collector | Tsuneo Namba, et al. | |
TMPW No. | 11983 |
The capital city, provincial capital city or the representative
location of its administrative area is indicated.
location of its administrative area is indicated.
Production area information
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Collection information
India,New Delhi
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Scientific information data base
Crude drug name | Ayurvedic name or Sanskrit name, English name | Karaskara, Nux Vomica | ||||
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Synonyms | Visavrksa, Kimkirata, Visa, Karaskara, Kimpaka, Visatindu, Visadruma, Garadruma, Ramyaphala, Kupaka, Kalakutaka, Visamusti, Kesamusti, Ksudramusti, Sumustika, Ksudrahva, Kakamustika | |||||
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Original plant name | Strychnos nux-vomica Linn. | |||||
Family name | Loganiaceae | |||||
Used part | Seed | |||||
Distribution area | Throughout India; Gorakhpur, Bihar, Orissa, Peninsular India, ascending upto 1500m in the hills. | |||||
Remarks | Common. | |||||
Common uses | Seeds are used as tonic, stimulant, antiinflammatory, analgesic and febrifuge. They are used in the treatment of nervous and general debility, arthritis, gout, sciatica, paralysis, neuralgia and sleeplessness. They are also used in the preparation of medicated products for the hair and scalp. Nux-vomica is a powerful poison in large doses, producing tetanic convulsions and eventually death. It forms an ingredient of an Ayurvedic formulation, Agnitundirasa, used as an antiulcer drug for peptic ulcers. | |||||
Therapeutic uses | Visa (poison), Kustha (skin diseases), Vatamaya (rheumatic disorder), Kandu (itching), Arsa (piles), Medas (obesity) | |||||
Chemical constituent | Others - Fleshy portion of the fruit contains strychnine, brucine and loganin. - Seeds, leaves, bark, and root contain strychnine and brucine. | |||||
Pharmacological effect | Therapeutic value of the drug is due to strychnine and brucine. Nux-vomica is a powerful poison in large doses, producing tetanic convulsions and eventually death. In comparatively lesser doses, it may result in mental derangement. The aqueous extract of drug possesses significant cardiotonic activity and is used in treatment of cardiovascular diseases. Nux-vomica forms an ingredient of an Ayurvedic drug formulation Agnitundi rasa used as an anti-cancer drug and for peptic ulcers. The drug possesses antiviral activity against chicken embryo virus. | |||||
Medical system | Ayurveda (Traditional Indian medicine) | |||||
Traditional concept | Rasa (Taste) | Tikta (Bitter), Katu (Pungent), Kasaya (Astringent) | ||||
Virya (Potency) | Usna (Hot) | |||||
Guna (Quality) | Laghu (Light), Ruksa (Dry), Tiksna (Sharp) | |||||
Vipaka (Post digestive taste) | Katu (Pungent) | |||||
Karma (General action) | Amahara (digesting the undigested), Madakara (intoxicating) | |||||
Dosakarma (Action on dosa) | Decreases Kapha Vata | |||||
Dhatukarma(Action on body tissues) | Asra (blood disorders), Meda (adipose tissue) | |||||
Mala (Action on excretory mechanism) | Grahi (constipative) | |||||
Formulation | Karaskara ghrta, Agnitundi, Visamusti, Navajivana, Laksmivilasa, Krmimudgara, Kupiluhingudi | |||||
Comments | Raw fruit is constipative, astringent, increasing Vata, light and cold. When it is ripe it is sweet, good for Kapha, rheumatism, diabetic types, disorders of Pitta and blood. The root which goes to the north is good. Fruits are also good for arthritic conditions, leucorrhoea/leucorrhea, dysuria, boils. Visavrksa, Visa, Visatindu, Visadruma, Visamusti, Garadruma denote the poisonous nature and antitoxic property of this. Ramyaphala denotes the beauty of the fruit. | |||||
References | Reference book Tips! | [2] Indian Medicinal Plants - A Compendium of 500 species, Varier, P.S., Orient Longman Ltd. Chennai (Madras) Vol. 5 (Repr.1997), pp 202-205. Glossary of Indian Medicinal Plants, 1956. Chopra, R.N., Nayar, S.L. and Chopra, I.C., Council of Scientific & Industrial Research, New Delhi. - New Edition (1996) National Institute Science Communication; Supplement p 36. Illustrated Manual of Herbal Drugs Used in Ayurveda, 1996. Sarin, Y.K., Council of Scientific & Industrial Research and Indian Council of Medical Research, New Delhi p 260. Ayurvedic Drugs and Their Plant Sources, 1994. Sivarajan, V.V. and Balachandran, I., Oxford & IBH Publishing Co. Pvt. Ltd., New Delhi p 218. Plants in Ayurveda (A Compendium of Botanical and Sanskrit Names), 1997. Abdul Kareem, M., Foundation for Revitalisation of Local Health Traditions, Bangalore 1540. Dravyagunavijnana, Vols. 1-5, reprint 1998. Sharma, P.V., Chowkhambha Bharati Academy, Varanasi Vol. 2, pp 83-86. Classical uses of Medicinal Plants, 1996. Sharma, P.V., Chaukhambha Visvabharati, Varanasi p 103. | ||||
Remarks | Root bark, ground into a fine paste with lime juice and made into pills, is said to be effectual in cholera. Leaves are applied as poultice to sloughing wounds and ulcers, especially in cases when maggots have formed. Wood is useful in dysentery, fevers and dyspepsia. Nux-vomica is an effective animal poison, and at present is used more as a poison than as a drug. Nux-vomica is one of the ingredients of the Unani drug Majnoon-e-Azaraqqi, used as a general and nervine tonic. | |||||
Last renewal date | 2023/12/21 |