Crude drug sample data base

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Crude drug name

Market nameKaranjua
Formal nameLatakaranja
Other names　　　

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Katkaranjia, Saagar gola (T), Natu koranja (B), Saagargola, Katkaleji (H), Gajagakayi (K), Kazhanchi kuru (M), Gach chakkay (Te), Kazhar shikkay (Ta), Kanju, Karanju, Karaunji (N), Kumburu (Sin)
English nameBonduc Nut, Fever Nut, Physic Nut
Original plant nameCaesalpinia bonduc (L.) Roxb. (= Caesalpinia bonducella Flem.), Bonduc Nut, Fever Nut, Physic Nut
Family nameCaesalpiniaceae (Former Leguminosae)
Used partClassificationPlant origin
Sub classification seed
Collection informationIndia, New Delhi, Hans Raj & Sons
Collection date1991/05/07
CollectorTsuneo Namba, et al.
TMPW No.12549

The capital city, provincial capital city or the representative　　
location of its administrative area is indicated.　　
Production area information
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28.6139391
77.20902120000005
Collection information
India,New Delhi
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Scientific information data base

Crude drug nameAyurvedic name or
Sanskrit name, English name		Latakaranja (C. bonduc), Bonduc Nut, Fever Nut, Physic Nut
SynonymsKantakaranja, Vallikantadhya, Svaratiktaka, Dvitribija, Triputa, Krminasini, Kubera, Kuberanetri, Kurangaksi, Patha, Dhenukaksi, Visalyaka, Kalavrnta, Duhsparsa, Virasya, Vajraviraka, Dhanadaksa, Kantaphala, Kuberaksa, Tiragandhi, Tirigicchi
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Original plant nameCaesalpinia bonduc (L.) Roxb. (= Caesalpinia bonducella Flem.)
Family nameCaesalpiniaceae (Former Leguminosae)
Used partRoot bark, Leaves, Seeds
Distribution areaThroughout the hotter parts of India, upto 1200m in the hills. Common in Bengal and South India.
RemarksCommon.
Common usesSeeds are antipyretic, antiperiodic, tonic, abortifacient and febrifuge. They are used in asthma, inflammatory swellings, intermittent fever, liver and splenic diseases, hydrocele and menstrual disorders.
Kernel powder is given to remove intestinal worms.
The fixed oil is used an embrocation to remove freckles from the face and for stopping discharges from the ear.
The seeds are an ingredient of Ayush-64 an Ayurvedic compound preparation used as an antimalarial drug and also to treat filariasis.
As an infusion they are used for curing cerebral haemorrhage/hemorrhage and infantile convulsions.
The fixed oil is antirheumatic and compares favourably with phenylbutazone.
Seed powder forms a household remedy for treatment of diabetes in Nicobar Islands.
Therapeutic usesMeha (diabetic types), Kustha (skin diseases), Arsa (piles), Vrana (wounds), Vata (rheumatic disorders), Antra (hydrocele)
Chemical constituentFatty acids
Palmitic acid (*C2), Stearic acid (*C2), Octadeca-4-enoic acid (*C2),
Octadeca-2,4-dienoic acid (*C2)

Diterpenoids
Neocaesalpin A (*C1), Neocaesalpin B (*C1), Neocaesalpin C (*C3), Neocaesalpin D (*C3), Caesaldekarin A (*C4), Caesaldekarin H (*C4), Caesaldekarin I (*C4), Caesaldekarin J (*C4), Caesaldekarin K (*C4), Caesaldekarin L (*C4), Demethylcaesaldekarin C (*C4), Caesalpinin B (*C5), Bondenolide (*C7, *C8), Bonducellpin A (*C9), Bonducellpin B (*C9), Bonducellpin C (*C9), Bonducellpin D (*C9), Caesalpin F (*C10), Caesaldekarin F (*C11), Caesaldekarin G (*C11),

Triterpenoids
alpha-Amyrin (*C6, *C8), beta-Amyrin (*C6, *C8), Lup-20(29)-en-3beta-ol (*C6, *C8), Lup-20(29)-en-3beta-yl acetate (*C6, *C8)

Sterols
beta-Sitosterol (*C6, *C8)

Steroid saponins & Sapogenins
beta-Sitosterol galactoside(*C6, *C8)

Chemical structure






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Pharmacological effectClinical studies have revealed that Ayush-64 administered orally at a dose level of 500mg/kg for 30 days did not produce any toxicity, qualifying the drug for clinical studies. Bonduc nuts have been used as an anti-periodic for a long time. Pharmacological trials have revealed diuretic and antipyretic activities of the nuts and have also proved efficaceous in diarrhoea. Seed powder showed hypoglycaemic activity in experimental animals.
Medical systemAyurveda (Traditional Indian medicine)
Traditional conceptRasa (Taste)Katu (Pungent), Kasaya (Astringent)
Virya (Potency)Usna (Hot)
Guna (Quality)Laghu (Light), Ruksa (Dry)
Vipaka
(Post digestive taste)		Katu (Pungent)
Karma
(General action)		Ropana (healing)
Dosakarma
(Action on dosa)		Decreases Kapha Vata
Mala
(Action on excretory mechanism)		Grahi (constipative)
Avayava
(Action on organ)		Yakrt (liver), Pliha (spleen)
FormulationVisamajvaraghni vati, Karanjadi vati, Kuberaksa vati, Visamajvarantaka curna.
CommentsSeeds increase digestive fire, good for colic, intestinal tumours/tumors.
Flowers are hot, bitter, Vata Kapha pacifying.
ReferencesReference book　

Tips！

[2] Indian Medicinal Plants - A Compendium of 500 species, Varier, P.S., Orient Longman Ltd. Chennai (Madras)
Vol. 1 (Repr.1996), pp 320-322.

Glossary of Indian Medicinal Plants, 1956. Chopra, R.N., Nayar, S.L. and Chopra, I.C., Council of Scientific & Industrial Research, New Delhi. - New Edition (1996) National Institute Science Communication; Supplement
pp 43-44.

Illustrated Manual of Herbal Drugs Used in Ayurveda, 1996. Sarin, Y.K., Council of Scientific & Industrial Research and Indian Council of Medical Research, New Delhi
p 62.

Ayurvedic Drugs and Their Plant Sources, 1994. Sivarajan, V.V. and Balachandran, I., Oxford & IBH Publishing Co. Pvt. Ltd., New Delhi
p 258.

Plants in Ayurveda (A Compendium of Botanical and Sanskrit Names), 1997. Abdul Kareem, M., Foundation for Revitalisation of Local Health Traditions, Bangalore
281.

Dravyagunavijnana, Vols. 1-5, reprint 1998. Sharma, P.V., Chowkhambha Bharati Academy, Varanasi
Vol. 2, pp 705-707.

Research paper*C1 Kinoshita, T., Kaneko, M., Noguchi, H. and Kitagawa, I.; Heterocycles,43, 409-14 (1996).
*C2 Rastogi, S., Shaw, A. K. and Kulshreshtha, D. K.; Fitoterapia, 67, 63-64 (1996).
*C3 Kinoshita, T.; Chem. Pharm. Bull., 48, 1375-77 (2000).
*C4 Lyder, D. L., Peter, S. R., Tinto, W. f., Bissada, S. M., McLean, S. and Reynolds, W. F.; J. Nat. Prod., 61, 1462-65 (1998).
*C5 Lyder, D. L., Tinto, W. F., Bissada, S. M., McLean, S. and Reynolds, W. F.; Heterocycles, 48, 1465-69 (1998).
*C6 Ali, M. S., Shameel, S., Ahmad, V. U. and Usmanghani, K.; Pak. j. Sci. Ind. Res., 40, 20-22 (1998).
*C7 Ahmad, V. U., Ali, M. S. and Usmanghani, K.; Z. Naturforsch., B: Chem. Sci., 53, 129 (1998).
*C8 Ahmad, V. U., Ali, M. S. and Usmanghani, K.; Z. Naturforsch., B: Chem. Sci., 52, 410-12 (1997).
*C9 McLean, S., Reynolds, W. F. and Yu, M.; J. Nat. Prod., 60, 1219-1221 (1997).
*C10 Pascoa, K. O., Burke, B. A. and Chan, W. R.; J. Nat. Prod., 49, 913-15 (1986).
*C11 Peter, S., Tinto, W. F., Mclean, S., Reynolds, W. F. and Yu, M.; Phytochemistry, 47, 1153-55 (1998).
RemarksIn Mauritius crushed seeds are given as an anthelmintic mixed with honey or castor oil. In the West Indies roasted seeds are made into a kind of coffee for diabetics.
Last renewal date2024/04/12
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