Crude drug sample data base
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Crude drug name | Market name | 地膚子 |
|---|---|---|
| Formal name | 地膚子 | |
| Japanese name | じふし, Jifushi | |
| Vernacular name | Difuzi | |
| Latin name | Kochiae Fructus (CP) | |
| English name | Belvedere Fruit (CP) | |
| Original plant name | Leonurus japonicus Houtt.1 & Leonurus sibiricus L.2 (3:1), Mehajiki1 and Hosobamehajiki2 (3:1) | |
| Family name | Labiatae | |
| Used part | Classification | Plant origin | Sub classification | fruit |
| Production area information | People's Republic of China | |
| Collection information | Hong Kong, Wing Tai Hong Medicine Co.,Ltd. | |
| Collection date | 1974/12/25 | |
| Identifier | Katsuko Komatsu | |
| TMPW No. | 3044 | |
Scientific information data base
| Common name | 地膚子, Difuzi, Kochiae Fructus (CP2020), Belvedere Fruit (CP2020) | ||||||
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| Original plant name | Kochia scoparia (L.) Schrader (B1), (Hōkigi) | ||||||
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| Family name | Chenopodiaceae | ||||||
| Used part | mature fruit | ||||||
| Official compendium | CP (2020 ed.) | ||||||
| Clinical application | As an antidote and diuretic, it is employed for the treatment of gonorrhea, difficulty in urination, edema, beriberi, skin lesion of dampness type, scabies, etc. | ||||||
| Medical system | Traditional Chinese medicine | ||||||
| Drug effect in traditional medicine | Traditional classification | Diuretics removing dampness | |||||
| Beneficial effect | [Property and Flavor] Cold; pungent and bitter. [Meridian Tropism] Kidney and bladder meridians. [Actions] To clear heat and drain dampness, and dispel wind to relieve itching. [Indications] Slow and painful urination, pudenda! itching, vaginal discharge, rubella, eczema, itching of skin. | ||||||
| Chemical constituent | Triterpenoids (*C1, C2, C3): Momordin Ic, Momordin IIc, Kochianoside I, Kochianoside II, Kochianoside III, Kochianoside IV, Scoparianoside A, Scoparianoside B, Scoparianoside C | ||||||
| Chemical structure |   
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| Pharmacological effect | Relieving the itching (momordin Ic), suppression of alcohol and sugar absorption (momordin Ic). | ||||||
| Classical reference (Chinese Herbal Classic "Zhenglei bencao") |  ※Click this image to see the actual image | ||||||
| Disease | Dysuria, Urodynia, Itching, Scabies, Eczema, Urticaria, Vulvitis, Vaginitis | ||||||
| Formulation | rarely used in formula | ||||||
| References | CP2020: Pharmacopoeia of the People's Republic of China 2020 edi. B1) Shoyakugaku Zassh, 39(3), 190-203(1985). B2) Shoyakugaku Zassh, 36(1), 6-10(1982). C1) Yakugaku Zasshi, 117(4), 193-201(1997). C2) Chem. Pharm. Bull., 45(6), 1052-1055(1997). C3) ibid., 45(8), 1300-1305(1997). | ||||||
| Remarks | The real Difuzi (地膚子) is thought to be the mature fruit of Kochia scoparia (L.) Schrad. of family Chenopodiaceae (Jap. name: Hōkigi). However, Chenopodium album L. (Jap. name: Shiroakaza), C. ficifolium Smith (Jap. name: Koakaza) and C. ambrosioides L. (Jap. name: Kearitasō) were also distributed in the market (B1). All of them belong to the same family as Difuzi. In addition, the fruit of Leonurus japonicus Houttuyn of family Labiatae (Jap. name: Mehajiki) and L. sibiricus L. (Jap. name: Hosobamehajiki) were found under the name of Difuzi in the Hong Kong market (B2). The fruit of Mehajiki or Hosobamehajiki is the original plant of "Chongweizi" (茺蔚子). The medicinal effects of Difuzi and Chongweizi are completely different except that both of them are used for eye problems. Chenopodium or Leonurus is not appropriate for use under the name of Difuzi derived from either genus. | ||||||
| Last renewal date | 2023/01/13 | ||||||
