Crude drug sample data base

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Crude drug name

Market name地夫只
Formal name地膚子
Japanese nameじふし, Jifushi
Vernacular nameDifuzi
Latin nameKochiae Fructus (CP)
English nameBelvedere Fruit (CP)
Original plant nameLeonurus japonicus Houtt.1, Leonurus sibiricus L.2, (Mahajiki1, Hosobamehajiki2)
Family nameLabiatae
Used partClassificationPlant origin
Sub classification fruit
Production area informationPeople's Republic of China
Collection informationPeople's Republic of China, Huijitangrongji co., Ltd.
Collection date1983/09/22
IdentifierKatsuko Komatsu
TMPW No.3066

Scientific information data base

Common name地膚子, Difuzi, Kochiae Fructus (CP2020), Belvedere Fruit (CP2020)
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Original plant nameKochia scoparia (L.) Schrader (B1), (Hōkigi)
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Family nameChenopodiaceae
Used partmature fruit
Official compendiumCP (2020 ed.)
Clinical applicationAs an antidote and diuretic, it is employed for the treatment of gonorrhea, difficulty in urination, edema, beriberi, skin lesion of dampness type, scabies, etc.
Medical systemTraditional Chinese medicine
Drug effect in
traditional medicine
Traditional
classification
Diuretics removing dampness
Beneficial effect[Property and Flavor] Cold; pungent and bitter.
[Meridian Tropism] Kidney and bladder meridians.
[Actions] To clear heat and drain dampness, and dispel wind to relieve itching.
[Indications] Slow and painful urination, pudenda! itching, vaginal discharge, rubella, eczema, itching of skin.
Chemical constituentTriterpenoids
(*C1, C2, C3):
Momordin Ic, Momordin IIc, Kochianoside I, Kochianoside II, Kochianoside III, Kochianoside IV, Scoparianoside A, Scoparianoside B, Scoparianoside C

Chemical structure



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Pharmacological effectRelieving the itching (momordin Ic), suppression of alcohol and sugar absorption (momordin Ic).
Classical reference
(Chinese Herbal Classic "Zhenglei bencao")
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DiseaseDysuria, Urodynia, Itching, Scabies, Eczema, Urticaria, Vulvitis, Vaginitis
Formulationrarely used in formula
ReferencesCP2020: Pharmacopoeia of the People's Republic of China 2020 edi.
B1) Shoyakugaku Zassh, 39(3), 190-203(1985).
B2) Shoyakugaku Zassh, 36(1), 6-10(1982).
C1) Yakugaku Zasshi, 117(4), 193-201(1997).
C2) Chem. Pharm. Bull., 45(6), 1052-1055(1997).
C3) ibid., 45(8), 1300-1305(1997).
RemarksThe real Difuzi (地膚子) is thought to be the mature fruit of Kochia scoparia (L.) Schrad. of family Chenopodiaceae (Jap. name: Hōkigi). However, Chenopodium album L. (Jap. name: Shiroakaza), C. ficifolium Smith (Jap. name: Koakaza) and C. ambrosioides L. (Jap. name: Kearitasō) were also distributed in the market (B1). All of them belong to the same family as Difuzi. In addition, the fruit of Leonurus japonicus Houttuyn of family Labiatae (Jap. name: Mehajiki) and L. sibiricus L. (Jap. name: Hosobamehajiki) were found under the name of Difuzi in the Hong Kong market (B2). The fruit of Mehajiki or Hosobamehajiki is the original plant of "Chongweizi" (茺蔚子). The medicinal effects of Difuzi and Chongweizi are completely different except that both of them are used for eye problems. Chenopodium or Leonurus is not appropriate for use under the name of Difuzi derived from either genus.
Last renewal date2023/01/13