Crude drug sample data base

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Crude drug name

Market nameGinari
Formal nameAgnimantha
Other names   

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Bhut-bhiravi, Ganiari (B), Ajetha, Arani, Ustabunda Arnee (H), Eegigida, Agnimanda, Takkite, Bachanige mara, Takkila (K), Munna, Munja (M), Pomanti, Pedda narua, Gaebbu nelli, Padmaka (Te), Munnay, Muney kiray, Munnai (Ta), Midi (Sin), Gineri (N)
Original plant namePremna corymbosa Rottl.
Family nameVerbenaceae
Used partClassificationPlant origin
Sub classification bark
Collection informationKingdom of Nepal, Kathmandu, N.K. Shakya
Collection date1991/04/28
CollectorTsuneo Namba, et al.
TMPW No.14653

The capital city, provincial capital city or the representative  
location of its administrative area is indicated.  
Production area information
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27.7172453
85.3239605
Collection information
Kingdom of Nepal,Kathmandu
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Scientific information data base

Crude drug nameAyurvedic name or
Sanskrit name, English name
Agnimantha
SynonymsVijaya, Jaya, Tarkari, Vaijayanti, Aranika, Arani, Kerurarani, Sriparni, Karnika, Ajakarni, Ganikarika, Nadeyi, Vahnimantha, Agnimathana, Ketu, Ananta, Tapana, Tejovrksa, Tanutvak, Mantha, Jangha, Gandhapatra, Gandhapuspa, Krsanuga.
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Original plant namePremna corymbosa Rottl.
Family nameVerbenaceae
Used partLeaves, Rootbark
Distribution areaOccurs along the coasts of India, Ceylon, Malaya, Andaman and Nicobar islands. It is common in the dry regions of Ceylon.
Common usesAgnimantha is astringent, cardiotonic, laxative, stomachic and tonic. This drug is used in the treatment of constipation, fever, cough, heart diseases, neurological diseases, rheumatism, anaemia, piles, asthma, bronchitis, skin diseases, abdominal diseases, dyspepsia, anorexia, flatulence, colic, oedema, poison, hepatopathy, diabetes and general debility. It is highly valued for its antiinflammatory property.
Therapeutic usesAgnimandya (loss of appetite), Ajirna (indigestion), Svayathu (swelling), Pandu (anaemia), Vibandha (constipation), Arsas (haemorrhoids/hemorrhoids).
Chemical constituentLignin
4-epi-Gummadiol-4-O-b-Dglucoptranoside (*C1)

Others
Premnafoliside (*C1), Verbascoside (*C2), 6-O-alpha-L-(2"-O-Caffeoyl)rhamnopyranosylcatalpol (*C2), 6-O-alpha-L-(2"-trans-p-Coumaroyl)rhamnopyranosylcatalpol (*C2), 6-O-alpha-L-(2"-cis-p-Coumaroyl)rhamnopyranosylcatalpol (*C2), 6-O-alpha-L-(3"-trans-p-Coumaroyl)rhamnopyranosylcatalpol (*C2)

Pharmacological effectGaniarine caused constriction of the blood vessels and raised the blood pressure whereas ganikarine had no such sympathominetic action. Premnine also causes dilation of the pupils. The antibiotic of phenolic nature, present in the root bark was found to be active against the Gram-positive organisms such as Micrococcus pyogenes var.aureus, Basillus subtilis and Streptococcus haemolyticus. Aqueous extract of the plant showed a powerful action on the uterus and gut of the experimental animals causing a marked increase in their activity.
Medical systemAyurveda (Traditional Indian medicine)
Traditional conceptRasa (Taste)Tikta (Bitter), Katu (Pungent), Kasaya (Astringent), Madhura (Sweet)
Virya (Potency)Usna (Hot)
Guna (Quality)Ruksa (Dry), Laghu (Light)
Vipaka
(Post digestive taste)
Katu (Pungent)
Karma
(General action)
Agnida (improves digestive fire), Amajit (helps in digestion), Anulomana (helps in the downward movement of vayu).
Dosakarma
(Action on dosa)
Decreases Kapha Vata
Traditional usage1. A decoction of Agnimantha (Premna corymbosa) in vasameha (a kind of polyuria) is recommended. It is a good remedy for obesity.

2. Patient of piles, in case of pain, should take after oily massage, tub bath in the decoction of the leaves of Agnimantha and Asmantaka (Ficus rumphii).

3. In granthi visarpa (a type of skin disease), paste of bamboo leaves and Agnimantha should be applied locally.

4. The part should be sprinkled with the decoction of Agnimantha and Karanja (Pongamia pinnata) in urustambha (a kind of Vata disorder). Moreover, the paste of these drugs pounded with cow's urine should be applied locally.

5. Root of (bark) Agnimantha pounded and taken with ghee alleviates sitapitta (a Pitta condition).

6. Application of the paste of Agnimantha bark pounded with goat's milk alleviates vyanga (a kind of skin disease).

7. Leaf juice is given in the convalescence period after fever to regain strength.
FormulationAgnimantha kasaya, Agnimanthamula kalka, Dasamularista.
Comments- It is mentioned that there are two varieties of agnimantha. Their synonyms have been used interchangeably. The two types of agnimantha mentioned in Raja nighantu are agnimantha and ksudragnimantha. The synonyms of agnimantha are also given for jayanti. For these, the commentators cite the latin name as Clerodendron phlomoides. In Nighanturatnakara, the two varieties are said to be brhat and laghu. Brhat variety is advised for internal use and laghu variety is advised for external purposes like poultice etc.

- Though tarkari is regarded as synonym of agnimantha, Dravyagunavijnana has considered agnimantha as Premna mucronata (big variety) and tarkari as Clerodendron phlomoides (small variety).

- In Ayurvedic formulary of India the latin name for agnimantha is C. phlomoides stating that Premna species can be used as substitute.

- It is called agnimantha because it results in fire by rubbing. It is called sriparna as it has beautiful flowers, ganikarika as it occurs in groups and it bestows health, tanutvak because its bark is thin. Gandhapuspa means its flowers are fragrant.
ReferencesReference book 

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[2] Indian Medicinal Plants - A Compendium of 500 species, Varier, P.S., Orient Longman Ltd. Chennai (Madras)
Vol. 4 (Repr.1997), pp 348-352.

Ayurvedic Drugs and Their Plant Sources, 1994. Sivarajan, V.V. and Balachandran, I., Oxford & IBH Publishing Co. Pvt. Ltd., New Delhi
p 21.

Medicinal plants (Indigenous and exotic) used in Ceylon, Vols. 1-5, 1982. Jayaweera, D.M.A., The National Science Council of Sri Lanka, Colombo
Vol. 5, p 173.

Dravyagunavijnana, Vols. 1-5, reprint 1998. Sharma, P.V., Chowkhambha Bharati Academy, Varanasi
Vol. 2, p 221.

Classical uses of Medicinal Plants, 1996. Sharma, P.V., Chaukhambha Visvabharati, Varanasi
p 5.

Research paper*C1 Yuasa, K., Ide, T., Otsuka, H. and Takeda, Y.; J. Nat. Prod., 56, 1695-99 (1993).
*C2 Otsuka, H., Watanabe, K., Yuasa, K., Ogami, C., Takushi, A. and Takeda, Y.; Phytochemistry, 32, 983-86 (1993).
RemarksIn Ayurveda, this is one of the ten drugs that constitute the group ‘dasamula’(a group of ten roots) which forms an ingredient of many important formulations.
Last renewal date2023/11/01