Crude drug sample data base

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Crude drug name

Market nameウワウルシ
Formal nameウワウルシ
Japanese nameうわうるし, Uwaurushi
Vernacular nameUvaursi
Latin nameUvae Ursi Folium (JP)
English nameBearberry Leaf (JP), Uva Ursi Leaf
Original plant nameArctostaphylos uva-ursi (L.) Spreng., (Kumakokemomo)
Family nameEricaceae
Used partClassificationPlant origin
Sub classification leaf
TMPW No.3239

Scientific information data base

Common nameウワウルシ, Uwaursi, Uvae Ursi Folium (JP18), Bearberry Leaf (JP18)
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Original plant nameArctostaphylos uva-ursi Sprengel, (Kumakokemomo)
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Family nameEricaceae
Used partleaf
Quality for selectionGood Uwaurushi is yellowish green and has few fractures. (TN)
Official compendiumJP XVIII
Clinical applicationAs a urinary tract disinfectant, astringent and diuretic, Uvae Ursi Folium is applied for pyelitis, urethritis and cystitis.
Medical systemEueropean herbal medicine
Chemical constituentMonoterpenoids
Iridoids:
(*C3):
Monotropein, Piceoside(p-hydroxy-acetophenone glucoside)

Triterpenoids
(*C1):
Ursolic acid

Flavones & Flavonols
(*C1):
Quercetin
(*C2):
Hyperoside

Tannins
(*C1):
Gallic acid, Ellagic acid
(*C2):
1,2,6-Trigalloylglucose, 1,3,6-Trigalloylglucose, 2,3,6-Trigalloylglucose, 1,2,3,6-Tetragalloylglucose, 1,2,3,4,6-Pentagalloylglucose

Other aromatic derivatives
(*C1):
Arbutin(5-7%), Methylarbutin, Hydroquinone
(*C2):
Galloylarbutin

Other nitrogen containing compounds
(*C1):
Allantoin

Chemical structure




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Pharmacological effectDisinfection （arbutin → hydroquinone）.
DNA sequenceAF297806, AF297761, AF091950, AF106821, AF106822
DiseasePyelitis, Nephritis, Cystitis,
FormulationUva Ursi Fluidextract,
Related drugsKokemomo (Vaccinium vitis-idaea L.)
ReferencesJP18: The 18th edition of the Japanese Pharmacopoeia.
C1)The Encyclopedia of Wakan-Yaku with Color Pictures Vol. II, pp 87-88.
C2)Outline of Pharmacognosy, a Textbook, p 251.
C3)Herbal Drugs and Phytopharmaceuticals(N.G.Bisset ed.), pp 510-512.
RemarksArctostaphylos uva-ursi (Jap. name: Kumakokemomo) is produced in Europe (Alps), Norway, North part of USA and Canada. The leaves of A. uva-ursi have been used by Vienna school since 18th century. In 19th century, each country started to list A. uva-ursi in its pharmacopoeia. In Japan, it has been listed in the Japanese Pharmacopoeia from the first (1886) to the present edition (C1). In Germany, tea and plant preparations of it are found in the market. These preparations must not be used with the drugs that cause acidic urine (C3).
Last renewal date2021/09/27
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