Crude drug sample data base

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Crude drug name

Market nameGodakaduru eta
Formal nameKaraskara
Other names   

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Kuchilaa, Nux vomica seed (T), Koonchilaa (B), Kuchilaa (H), Musti bija (K), Kanniram (M), Mustimanu (Te), Ettikottai (Ta), Basa musta (Ti), Kajara, Kucila (N), Godakadur (Sin)
English nameNux Vomica
Original plant nameStrychnos nux-vomica Linn., Nux Vomica
Family nameLoganiaceae
Used partClassificationPlant origin
Sub classification seed
Collection informationDemocratic Socialist Republic of Sri Lanka, Colombo, W. Wilbert & Co.
Collection date1982/02/01
CollectorTsuneo Namba, et al.
TMPW No.11736

The capital city, provincial capital city or the representative  
location of its administrative area is indicated.  
Production area information
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6.9270786
79.86124300000006
Collection information
Democratic Socialist Republic of Sri Lanka,Colombo
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Scientific information data base

Crude drug nameAyurvedic name or
Sanskrit name, English name
Karaskara, Nux Vomica
SynonymsVisavrksa, Kimkirata, Visa, Karaskara, Kimpaka, Visatindu, Visadruma, Garadruma, Ramyaphala, Kupaka, Kalakutaka, Visamusti, Kesamusti, Ksudramusti, Sumustika, Ksudrahva, Kakamustika
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Original plant nameStrychnos nux-vomica Linn.
Family nameLoganiaceae
Used partSeed
Distribution areaThroughout India; Gorakhpur, Bihar, Orissa, Peninsular India, ascending upto 1500m in the hills.
RemarksCommon.
Common usesSeeds are used as tonic, stimulant, antiinflammatory, analgesic and febrifuge. They are used in the treatment of nervous and general debility, arthritis, gout, sciatica, paralysis, neuralgia and sleeplessness. They are also used in the preparation of medicated products for the hair and scalp. Nux-vomica is a powerful poison in large doses, producing tetanic convulsions and eventually death. It forms an ingredient of an Ayurvedic formulation, Agnitundirasa, used as an antiulcer drug for peptic ulcers.
Therapeutic usesVisa (poison), Kustha (skin diseases), Vatamaya (rheumatic disorder), Kandu (itching), Arsa (piles), Medas (obesity)
Chemical constituentOthers
- Fleshy portion of the fruit contains strychnine, brucine and loganin.

- Seeds, leaves, bark, and root contain strychnine and brucine.

Pharmacological effectTherapeutic value of the drug is due to strychnine and brucine. Nux-vomica is a powerful poison in large doses, producing tetanic convulsions and eventually death. In comparatively lesser doses, it may result in mental derangement.

The aqueous extract of drug possesses significant cardiotonic activity and is used in treatment of cardiovascular diseases.

Nux-vomica forms an ingredient of an Ayurvedic drug formulation Agnitundi rasa used as an anti-cancer drug and for peptic ulcers. The drug possesses antiviral activity against chicken embryo virus.
Medical systemAyurveda (Traditional Indian medicine)
Traditional conceptRasa (Taste)Tikta (Bitter), Katu (Pungent), Kasaya (Astringent)
Virya (Potency)Usna (Hot)
Guna (Quality)Laghu (Light), Ruksa (Dry), Tiksna (Sharp)
Vipaka
(Post digestive taste)
Katu (Pungent)
Karma
(General action)
Amahara (digesting the undigested), Madakara (intoxicating)
Dosakarma
(Action on dosa)
Decreases Kapha Vata
Dhatukarma(Action
on body tissues)
Asra (blood disorders), Meda (adipose tissue)
Mala
(Action on excretory mechanism)
Grahi (constipative)
FormulationKaraskara ghrta, Agnitundi, Visamusti, Navajivana, Laksmivilasa, Krmimudgara, Kupiluhingudi
CommentsRaw fruit is constipative, astringent, increasing Vata, light and cold. When it is ripe it is sweet, good for Kapha, rheumatism, diabetic types, disorders of Pitta and blood. The root which goes to the north is good. Fruits are also good for arthritic conditions, leucorrhoea/leucorrhea, dysuria, boils.

Visavrksa, Visa, Visatindu, Visadruma, Visamusti, Garadruma denote the poisonous nature and antitoxic property of this. Ramyaphala denotes the beauty of the fruit.
ReferencesReference book 

Tips!

[2] Indian Medicinal Plants - A Compendium of 500 species, Varier, P.S., Orient Longman Ltd. Chennai (Madras)
Vol. 5 (Repr.1997), pp 202-205.

Glossary of Indian Medicinal Plants, 1956. Chopra, R.N., Nayar, S.L. and Chopra, I.C., Council of Scientific & Industrial Research, New Delhi. - New Edition (1996) National Institute Science Communication; Supplement
p 36.

Illustrated Manual of Herbal Drugs Used in Ayurveda, 1996. Sarin, Y.K., Council of Scientific & Industrial Research and Indian Council of Medical Research, New Delhi
p 260.

Ayurvedic Drugs and Their Plant Sources, 1994. Sivarajan, V.V. and Balachandran, I., Oxford & IBH Publishing Co. Pvt. Ltd., New Delhi
p 218.

Plants in Ayurveda (A Compendium of Botanical and Sanskrit Names), 1997. Abdul Kareem, M., Foundation for Revitalisation of Local Health Traditions, Bangalore
1540.

Dravyagunavijnana, Vols. 1-5, reprint 1998. Sharma, P.V., Chowkhambha Bharati Academy, Varanasi
Vol. 2, pp 83-86.

Classical uses of Medicinal Plants, 1996. Sharma, P.V., Chaukhambha Visvabharati, Varanasi
p 103.

RemarksRoot bark, ground into a fine paste with lime juice and made into pills, is said to be effectual in cholera. Leaves are applied as poultice to sloughing wounds and ulcers, especially in cases when maggots have formed. Wood is useful in dysentery, fevers and dyspepsia.

Nux-vomica is an effective animal poison, and at present is used more as a poison than as a drug. Nux-vomica is one of the ingredients of the Unani drug Majnoon-e-Azaraqqi, used as a general and nervine tonic.
Last renewal date2023/12/21