Crude drug sample data base

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Crude drug name

Market name水梔子
Formal name山梔子
Japanese nameさんしし, Sanshishi
Vernacular nameShuizhizi
Latin nameGardeniae Fructus (JP), (CP)
English nameGardenia Fruit (JP), Cape Jasmine Fruit (CP)
Used partClassificationPlant origin
Sub classification fruit
Production area informationPeople's Republic of China, Guangxi Zhuangzu Autonomous Region
Collection informationJapan（ToS）, Osaka Pref., Tochimoto Tenkaido Co., Ltd. [Non-commercial Sample]
Collection date2019/07/19
CollectorKatsuko Komatsu
TMPW No.30110

The capital city, provincial capital city or the representative　　
location of its administrative area is indicated.　　
22.817002
108.36654299999998
Production area information
People's Republic of China,Guangxi Zhuangzu Autonomous Region
https://ethmed.toyama-wakan.net/img/pin_san.png
34.6937249
135.5022535
Collection information
Japan（ToS）,Osaka Pref.
https://ethmed.toyama-wakan.net/img/pin_nyu.png

Scientific information data base

Common name山梔子, Shanzhizi, Zhizi, Gardeniae Fructus (JP18), (CP2020), Gardenia Fruit (JP18), Cape Jasmine Fruit (CP2020)
Synonyms水梔子, 梔子
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Original plant nameGardenia jasminoides J. Ellis1, Gardenia jasminoides f. grandiflora Makino, Gardenia jasminoides var. radicans Makino, (Kuchinashi1, Korinkuchinashi, Kokuchinashi)
original plant image
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Family nameRubiaceae
Used partfruit
Quality for selectionThe shape of Shanzhizi is round and that of Shuizhizi is slender. In general, the round type, which is massive and ponceau, is higher in quality. (TN)
Official compendiumJP XVIII, CP (2020 ed.)
Clinical applicationAs an antiinflammatory drug, hemostatic, sedative, for normalizing the function of gallbladder, shanzhizi is applied for fidgetiness (mental instability) due to congestion or inflammation, hematemesis, hematuria, congestion and jaundice. For external use, the powder of shanzhizi should be blended with the powder of huangbo and other materials, then kneaded with vinegar. It is applied to bruise externally.
Medical systemTraditional Chinese medicine
Drug effect in
traditional medicine		Traditional
classification		Drugs for reducing intense internal heat
Beneficial effect[Property and Flavor] Cold; bitter.
[Meridian Tropism] Heart, lung meridians and triple energizers.
[Actions] To purge fire to relieve vexation, clear heat and drain dampness, cool the blood, remove toxin;
topically disperse swelling and relieve pain.
[Indications] Febrile disease with vexation, dampness-heat jaundice, stranguria with slow pain, blood heat with hematemesis, red painful swelling eye, fire-toxin sore and ulcer; topically for sprain and contusions.
Chemical constituentMonoterpenoids
Iridoids:
(*C1):
Gardenoside, Geniposide, Genipin, Genipin 1-beta-gentiobioside, Shanzhiside, Methyl decacetylasperuloside, Geniposidic acid, 10-Acetylgeniposide, Gardoside, Scandoside methyl ester
(*C2):
Geniposide, Gardenoside, 以下代謝物 [The following compounds are the metabolites] Genipinine, Genipinine monoacetate, Gardenogenin A, Gardenogenin B, Gardenine

Carotenoids
(*C1):
Crocin (Crocetin + Gentiobiose)

Other aromatic derivatives
(*C1):
p-オキシケイヒ酸誘導体

Chemical structure



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Pharmacological effectAperient，stimulation of bile secretion，suppression of gastric juice secretion，analgesic (geniposide）．Stimulation of bile secretion，suppression of increase in bilirubin and cholesterol in blood (crocin，crocetin，extract）．Hypotensive （extract）．
DNA sequenceAF201044, AJ286697, AF102426, AJ224833; Traditioal Medical & Parmaceutical Database.
Classical reference
(Chinese Herbal Classic "Zhenglei bencao")		※Click this image to see the actual image
Disease, High fever, Disturbance of consciousness, Red eye, Feeling of bitter in the mouth, Thirst, Jaundice, Urodynia, Dysuria, Cloudy urine, Hematemesis, Nasal hemorrhage, Hematochezia, Hematuria, Internal bleeding, Pyogenic dermatosis, Swelling and pain due to contusion, Burn
FormulationInchinkoto, Inchinsan, Unseiin, Ogesan, Orengedokuto, Orengedokuto, Orenshodokuin, Kagenshosaikoto, Kagenryokakusan, Kagenryokakusan'ippo, Kakkonkokato, Kamikihito, Kamishokankyoto, Kamishoyosan, Kamishoyosangoshimotsuto, Kamihachimyakusan, Kijitsushishishito, Kijitsushishidaioshito, Kumisaikoto, Keigairengyoto, Keigairengyoto, Gorinsan, Saikoseikansan, Shishikankyoto, Shishikanzoshito, Shishikobokuto, Shishishito, Shishishokyoshito, Shishidaioto, Shishihakuhito, Shijunseiryoin, Jijinmeimokuto (Jinkimeimouto), Shaito, Junkiwachuto, Shin'iseihaito, Jinkimeimokuto, Seiishakato, Seiinrikakuto, Seijobofuto, Seineitsugeutsuto, Seihaito, Seiryoin, Senkanmeimokuto, Jiohanho, Jishusabiho, Tonsonto, Naisoorento, Bofutsushosan, Rikakuto, Ryutan-shakan-to, Ryutan-shakan-to, Ryokakusan, Rokuutsuto, Kaishun'inchinsan, Compound Phellodendron Powder for Cataplasm
ReferencesJP18: The 18th edition of the Japanese Pharmacopoeia.
CP2020: Pharmacopoeia of the People's Republic of China 2020 edi.
C1) The Encyclopedia of Wakan-Yaku with Color Pictures Vol. I, pp 187-188.
C2) Planta Med.,57,536(1991).
RemarksG. jasminoides has a lot of variants. They are called "Shanzhizi", "Shuizhizi", "Hongzhizi" and "Huangzhizi" according to the color or shape. "Shanzhizi" is the round hand type and "Shuizhizi" is the long hand type. Kuchinashi (Jap. name), a kind of Korinkuchinashi, is G. jasminoides Ellis forma grandiflora (Lour.) Makino. The Japanese Pharmacopoeia does not define Kuchinashi as a variant, but as a breed of G. jasminoides. The original plant of "Shuizhizi" is G. jasminoides Ellis forma longicarpa Z.W. Xie et Okada. "Shanzhizi" has been frequently used as a natural yellow dye since ancient times.
Last renewal date2023/03/23
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