Crude drug sample data base
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Crude drug name | Market name | センブリ |
|---|---|---|
| Formal name | センブリ | |
| Japanese name | せんぶり, Semburi | |
| Vernacular name | Semburi | |
| Latin name | Swertiae Herba (JP) | |
| English name | Swertia Herb (JP) | |
| Original plant name | Swertia japonica Makino, (Semburi) | |
| Family name | Gentianaceae | |
| Used part | Classification | Plant origin | Sub classification | whole plant |
| Production area information | Japan, Tohoku District | |
| Collection information | Japan, Gifu Pref. , Alps Pharmaceutical lnd. Co., Ltd. | |
| Collection date | 2005/04/28 | |
| Collector | Katsuko Komatsu | |
| Remarks | Lot.05D5S Production area: Akita/Yamagata Pref. 2004/06/21 | |
| TMPW No. | 30203 | |
The capital city, provincial capital city or the representative
location of its administrative area is indicated.
location of its administrative area is indicated.
39.835580038824546
140.88960752499997
Production area information
Japan,Tohoku District
https://ethmed.toyama-wakan.net/img/pin_san.png
35.3912272
136.72229059999995
Collection information
Japan,Gifu Pref.
https://ethmed.toyama-wakan.net/img/pin_nyu.png
Scientific information data base
| Common name | センブリ, Semburi, Swertiae Herba (JP18), Swertia Herb (JP18) | ||||||
|---|---|---|---|---|---|---|---|
| Synonyms | 当薬 | ||||||
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| Original plant name | Swertia japonica Makino, (Semburi) | ||||||
| original plant image |
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| Family name | Gentianaceae | ||||||
| Used part | whole plant in flowering time | ||||||
| Quality for selection | Good Semburi has lots of flowers and leaves, which are harvested on the early stages of inflorescence. (TN) | ||||||
| Official compendium | JP XVIII | ||||||
| Clinical application | It is an aromatic stomachic. It is also used to stimulate hair growth, provide sadation and lessen inflammation. | ||||||
| Medical system | Folk medicine | ||||||
| Chemical constituent | Monoterpenoids Secoiridoids: (*C1): Swertiamarin, Sweroside, Gentiopicroside, Amarogentin, Amaroswerin S. japonica (*C6,C7): Swertiamarin, Sweroside, 以下代謝物 [The following compounds are the metabolites] 4,4beta-5alpha,6alpha-Tetrahydro-5beta-hydroxymethyl-6beta-methyl-1H,3H-pyrano[3,4-c]pyran-1-one, Epinaucledal, Naucledal (*C9): Gentiopicrin Triterpenoids (*C1): Oleanolic acid, Thysanolactone Xanthones (*C1): Norswertianin, Swertianin, Methylswertianin, Swertianolin, Desmethylbellidifolin, Bellidifolin(=Swertianol), Methylbellidifolin S. japonica (*C2-C5): Tetrahydroswertianolin, 1,3,6,7-Tetrahydroxyxanthone S. chirata (*C8): Mangiferin, 1,3,6,7-Tetrahydroxyxanthone (*C9): Swertinogen Flavonoids (*C1): Swertisin, Swertiajaponin, Homoorientin, Isovitexin S. japonica (*C4,C5): Homoorientin, 6-C-Glucosyleriodictyol, (±)-Eriodictyol, Luteolin Phenol derivatives S. japonica (*C4,C5): Phloroglucinol Other aromatic derivatives S. japonica (*C6,C7): Erythrocentaurin, Hydroxymethyl isochroman-1-one Pyridine alkaloids S. japonica (*C6): Gentianine | ||||||
| Chemical structure |    
※画像をクリックすると、拡大して表示されます。 | ||||||
| Pharmacological effect | Secretion of gastric juices (gentiopicrin：enhancement；genitianine：suppression；swertinogen：enhancement at low doses and suppression at high doses）．Enhanced secretion of bile and pancreatic juice. Antiulcer（gentianine）. Improvement of function of liver，dilatation of capillary，activation of skin cells, stimulation of hair growth （swertinogen）. Hypoglycemic （bellidifolin）． | ||||||
| DNA sequence | AF102486, AJ010528, AJ011457; Traditioal Medical & Parmaceutical Database. | ||||||
| Disease | Stomachache, Abdominal pain | ||||||
| Formulation | Bitter Tincture, Sodium Bicarbonate and Bitter Tincture, Swertia and Sodium Bicarbonate Powder, Magnesium Sulfate Mixture | ||||||
| Related drugs | Chirayta (see "Remarks") | ||||||
| References | JP18: The 18th edition of the Japanese Pharmacopoeia. C1)The Encyclopedia of Wakan-Yaku with Color Pictures Vol. II, pp 46-47. C2)Chem.Pharm.Bull.,45,567(1997). C3)Chem.Pharm.Bull.,45,1823(1997). C4)Natural Drugs and the Digestive Tract,299(1992). C5)J.Nat.Prod.,51,874(1988). C6)Planta Med.,55,147(1989). C7)Shoyakugaku Zasshi,44,122(1990). C8)Phytochemistry,28,1289(1989). C9)Pharmacology of Medicinal Herbs in East Asia, pp 237-240. | ||||||
| Remarks | It is a typical Japanese folk medicine. It was blended in Japanese medicine "Hangontan" as the substitute for Chinese crude drug "Huhuanglian". "Huhuanglian" is the rhizome of Picrorrhiza scrophulariiflora Pennell or P. kurrooa Royle ex Benth. Chirayta (Chirata, Chiretta, Kiratatikta) is the whole plant of Swertia chirayta (Roxb.) Karst. and listed in the medical book of Ayurveda, "Caraka Samhita". It has effect of decreasing excess Kapha Dosa, or phlegmatic temperament, and is applied to treat diseases of blood vessels and skin. | ||||||
| Last renewal date | 2022/10/25 | ||||||
