Crude drug sample data base
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Crude drug name | Market name | 山豆根 |
|---|---|---|
| Formal name | 山豆根 | |
| Japanese name | さんずこん, Sanzukon | |
| Vernacular name | Shandougen | |
| Latin name | Sophorae Subprostratae Radix (Non-JPS), Sophorae Tonkinensis Radix et Rhizoma (CP) | |
| English name | Sophora Subprostrata Root (Non-JPS), Vietnamese Sophora Root (CP) | |
| Used part | Classification | Plant origin | Sub classification | root + rhizome |
| Production area information | People's Republic of China, Guangxi Zhuangzu Autonomous Region | |
| Collection information | Japan（ToS）, Osaka Pref. , Tochimoto Tenkaido Co., Ltd. [Non-commercial Sample] | |
| Collection date | 2020/6/22 | |
| Collector | Katsuko Komatsu | |
| TMPW No. | 30559 | |
The capital city, provincial capital city or the representative
location of its administrative area is indicated.
location of its administrative area is indicated.
22.817002
108.36654299999998
Production area information
People's Republic of China,Guangxi Zhuangzu Autonomous Region
https://ethmed.toyama-wakan.net/img/pin_san.png
34.6937249
135.5022535
Collection information
Japan（ToS）,Osaka Pref.
https://ethmed.toyama-wakan.net/img/pin_nyu.png
Scientific information data base
| Common name | 山豆根, Shandougen, Sophorae Subprostratae Radix (Non-JPS2022), Sophorae Tonkinensis Radix et Rhizoma (CP2020), Sophora Subprostrata Root (Non-JPS2022), Vietnamese Sophora Root (CP2020) | |||||
|---|---|---|---|---|---|---|
| Synonyms | 広豆根 | |||||
| crude drug image |
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| Original plant name | Sophora subprostrata Chun et T. Chen (= Sophora tonkinensis Gagnep.) | |||||
| Family name | Leguminosae | |||||
| Used part | root and rhizome | |||||
| Official compendium | Non-JPS (2022), CP (2020 ed.) | |||||
| Clinical application | As an antidote, painkiller, anti inflammatory drug and antitumor drug, shandougen is applied for sore throat and painful swelling, early stage of lung cancer and pharyngeal cancer. It is also applied for inflammation of uterine cervix and stomatitis externally. | |||||
| Medical system | Traditional Chinese medicine | |||||
| Drug effect in traditional medicine | Traditional classification | Febrifugal and detoxicant drugs | ||||
| Beneficial effect | [Property and Flavor] Cold; bitter; toxic. [Meridian Tropism] Lung and stomach. [Actions] To clear heat, remove toxin, disperse swelling and soothe the throat. [Indications] Retained fire toxin bind, tonsillitis and throat impediment, swelling and sore throat and gum, mouth and tongue sores. | |||||
| Chemical constituent | Triterpenoid saponins (*C1): Lupeol Sterols (*C1): beta-Sitosterol Isoflavones (*C1): l-Maackiain, Trifolirhizin, l-Pterocarpin, Genistein Chalcones, Dihydrochalcones & Aurones (*C1): Sophoradin, Sophoranone, Sophoradochromene, Sophoranochromene Phenol derivatives (*C1): trans-Caffeic acid docosylesterを主にした新phenol性物質 Quinolizidine alkaloids (*C1): Matrine, Oxymatrine, Anagyrine, N-Methylcytisine Isoquinoline alkaloids Menispermum dauricum (*C2): Dauricoside | |||||
| Chemical structure |    
※画像をクリックすると、拡大して表示されます。 | |||||
| Pharmacological effect | Antitumor, suppression of stress-induced ulcer (extract). antitumor（matrine）．Suppression of ulcer induced by pyloric ligation and stress-induced ulcer，suppression of gastric juices （sophoradin, sophoranone）． | |||||
| DNA sequence | AF142693, AF309829, AF311369, AF309828, AF123452, AF142693, AF174638; Traditioal Medical & Parmaceutical Database. | |||||
| Classical reference (Chinese Herbal Classic "Zhenglei bencao") |  ※Click this image to see the actual image | |||||
| Disease | Swelling and pain of the throat, Swelling and pain of the root of tooth, Early cancer, Skin ulcer, Cervicitis, Stomatitis | |||||
| Formulation | rarely used in formula | |||||
| Related drugs | Beidougen (see "Remarks") | |||||
| References | Non-JPS2022: The Japanese standards for non-Pharmacopoeial crude drugs 2022. CP2020: Pharmacopoeia of the People's Republic of China 2020 edi. C1) The Encyclopedia of Wakan-Yaku with Color Pictures Vol. I, pp 10-12. C2) Chem.Pharm.Bull.,41,1866-1868(1993). [PMID: 8281582] | |||||
| Remarks | "Shandougen" has several kinds of origin. For the present, the "Shandougen", imported from China, belongs to genus Sophora. It is produced in Guangxi Zhuang Autonomous Region. "Shandougen" of Northeast and North China called "Beidougen", is the rhizome of Menispermum dauricum DC. of family Menispermaceae (Jap. Name: "Komorikazura"). In Hubei, Henan, Shanxi, Gansu, Shanxi, Jiangsu and others, "Shandougen" is the root of many kinds of genus Indigofera, family Leguminosae, such as Indigofera amblyantha Craib, I. fortunei Craib and I. ichangensis Craib. | |||||
| Last renewal date | 2022/07/19 | |||||
