Crude drug sample data base
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The capital city, provincial capital city or the representative
location of its administrative area is indicated.
location of its administrative area is indicated.
34.341574
108.93976999999995
Production area information
People's Republic of China,Shaanxi Prov.
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34.6937378
135.50216509999996
Collection information
Japan,Osaka Pref.
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Scientific information data base
Common name | 遠志, Yuanzhi, Polygalae Radix (JP18, CP2020), Polygala Root (JP18), Thinleaf Milkwort Root (CP2020) | |||||
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Synonyms | 大遠志,志通 | |||||
crude drug image |
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Original plant name | Polygala tenuifolia Willdenow (rarely Polygala sibirica Linn. ), (Itohimehagi) | |||||
original plant image |
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Family name | Polygalaceae | |||||
Used part | root or root bark | |||||
Quality for selection | Good Yuanzhi is enlarged, thick and has irregular surface. Neither thin nor stiff one is good. (TN) | |||||
Official compendium | JP XVIII, CP (2020 ed.) | |||||
Clinical application | As a tranquilizer, expectorant and tonic, Yuanzhi is applied for forgetfulness, dream-disturbed sleep, cough, phlegm-heat and carbuncles. | |||||
Medical system | Traditional Chinese medicine | |||||
Drug effect in traditional medicine | Traditional classification | Sedatives and tranquilizer | ||||
Beneficial effect | [Property and Flavor] Warm; bitter and pungent. [Meridian Tropism] Heart, kidney and lung meridians. [Actions] To tranquilize the mind and replenish wisdom, coordinate the heart and kidney, dispel phlegm, and disperse swelling. [Indications] Insomnia and dream-disturbed sleep, forgetfulness and fright palpitations caused by heart-kidney non-interaction pattern; absentmindedness, ungratifying expectoration of phlegm, sore and ulcer, swelling and toxin, breast swelling and pain. | |||||
Chemical constituent | Monosaccharides (*C1): Polygalitol Triterpenoids (*C1): beta-Amyrin Triterpenoid saponins (*C1): Onjisaponin A(=Senegin IV), Onjisaponin B(=Senegin III), Onjisaponin C, Onjisaponin D, Onjisaponin E, Onjisaponin F, Onjisaponin G Phenylpropanoids (*C1): 3,4,5-Trimethoxycinnamic acid Xanthones (*C1): 3-Hydroxy-2,6,7,8-tetramethoxyxanthone, 2,6,7,8-Tetramethoxyxanthone, 2,3,6,7,8-Pentamethoxyxanthone Flavanones & Dihydroflavonols (*C1): Onsitin | |||||
Chemical structure |
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Pharmacological effect | Inhibition of phosphodiesterase (onjisaponin B,E,F),central nervous system inhibition (onjisaponin F). | |||||
DNA sequence | U42797, L01945 | |||||
Classical reference (Chinese Herbal Classic "Zhenglei bencao") | ※Click this image to see the actual image | |||||
Disease | Palpitation, Insomnia, Amnesia, Dementia, Cough, A lot of sputum, Pyogenic dermatosis | |||||
Formulation | Kamiuntanto, Kamikihito, Kihito, Shoshinto, Ninjin-yoei-to, Ryukotsuto | |||||
Related drugs | Senegae Radix | |||||
References | JP18: The 18th edition of the Japanese Pharmacopoeia. CP2020: Pharmacopoeia of the People's Republic of China 2020 edi. C1)The Encyclopedia of Wakan-Yaku with Color Pictures Vol. I, pp 173-174. | |||||
Remarks | The root bark without woody parts is called Yuanzhirou (遠志肉), Zhitong (志通) or Yuanzhitong (遠志筒), and considered to be superior in quality. | |||||
Last renewal date | 2021/09/27 | |||||