Crude drug sample data base

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Crude drug name

Market name山帰来
Formal name山帰来
Japanese nameさんきらい, Sankirai
Vernacular nameTufuling (土茯苓)
Latin nameSmilacis Rhizoma (JP), Smilacis Glabrae Rhizoma (CP)
English nameSmilax Rhizome (JP), Glabrous Greenbrier Rhizome (CP)
Original plant nameSmilax glabra Roxb.
Family nameLiliaceae
Used partClassificationPlant origin
Sub classification tuber
Production area informationPeople's Republic of China, Henan Prov.
Collection informationJapan, Osaka Pref., Tochimoto Tenkaido Co., Ltd.
Collection date2020/7/3
CollectorKatsuko Komatsu
RemarksJoint Usage / Research Center Project 2020
TMPW No.30623

The capital city, provincial capital city or the representative  
location of its administrative area is indicated.  
34.746611
113.62532799999997
Production area information
People's Republic of China,Henan Prov.
https://ethmed.toyama-wakan.net/img/pin_san.png
34.6937378
135.50216509999996
Collection information
Japan,Osaka Pref.
https://ethmed.toyama-wakan.net/img/pin_nyu.png

Scientific information data base

Common name土茯苓, Tufuling, Smilacis Rhizoma (JP18), Smilacis Glabrae Rhizoma (CP2020), Smilax Rhizome (JP18), Glabrous Greenbrier Rhizome (CP2020)
Synonyms山帰来 (Sankirai)
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Original plant nameSmilax glabra Roxburgh
original plant image
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Family nameLiliaceae
Used partrhizome
Quality for selectionGood Tufuling is pale reddish brown. The inside is powder-like white. The one which has rotten or blighted parts is not good. (TN)
Official compendiumJP XVIII, CP (2020 ed.)
Clinical applicationAs a remedy for poison, removing dampness, clearing heat and eliminating syphilis, it is used to treat chronic skin disease, dermatitis and contracture of limbs and muscle pain caused by syphilis or mercury poisoning. It is also used as a supplementary drug for acute hepatitis.
Medical systemTraditional Chinese medicine
Drug effect in
traditional medicine
Traditional
classification
Febrifugal and detoxicant drugs
Beneficial effect[Property and Flavor] Neutral; sweet and bland.
[Meridian Tropism] Liver and stomach meridians.
[Actions] To remove toxin, remove dampness, relieve and comfort joints.
[Indications] Spasm of limbs, pain in the sinews and bones caused by syphilis or mercury poisoning, dampness-heat strangury and the turbid, vaginal discharge, swelling abscess, scrofula, scabies, and tinea.
Chemical constituentPolysaccharides
(*C1):
澱粉/starch

Steroid saponins & Sapogenins
S. china (*C1):
Smilax-saponin A, Smilax-saponin B, Smilax-saponin C

Phenylpropanoids
S. glabra (*C2)
5-0-caffeoylshikimicacid

Chromones
S. glabra (*C2)
Eurryphin

Flavanones & Dihydroflavonols
S. china (*C1):
Astilbin, Distylin, Engeliten (= Engelitin)
S. glabra (*C2)
Smitilbin, Engeletin, Astilbin, Dihydroquercetin

Chemical structure

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Pharmacological effectAntiinflammation, antisyphilic, anticarcinogenesis (extract, resveratrol), suppression of autoimmune hepatopathy (eurryphin, resveratrol, smitilbin, eugeletin, astilbin).(C2)
DNA sequenceAB040204, AF207022, D28333, U82645, L39853, L39854
DiseaseSyphilis, Pyogenic dermatosis, Eczema, Psoriasis, Swelling and pain of joint
FormulationKagawagedokuzai, Katsuketsugedokuto, Kikyogedokuto, Shogedokuto, Daibyakuchuin, Hachimitaikaho
Related drugsBakkatsu, the rhizome of S. china
ReferencesJP18: The 18th edition of the Japanese Pharmacopoeia.
CP2020: Pharmacopoeia of the People's Republic of China 2020 edi.
C1)The Encyclopedia of Wakan-Yaku with Color Pictures Vol. I, pp 13.
C2)Planta Med., 65, 56-59(1999).
RemarksJapanese Sankirai (山帰来) is the rhizome of Smilax chinaL., (Jap. name: Sarutoriibara). It has been famous for treating syphilis. In Japan, it was used in Muromachi period according to an old record. It seems that the treatment method was developed shortly after syphilis came from South America. There is a myth that Sankirai, literally means returning from mountains, was named because syphilis patients returned alive from mountains after going there alone and taking the roots. However, this myth is questionable. Assumably, Sankiryo, another name for Tufuling, was the original name and had changed the accent into Sankirai (TN).
In China the rhizome of S. china is referred to as Bakkatsu and used to eliminate dampness, promote urination and and reduce edema.
Last renewal date2021/09/27