Crude drug sample data base

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Crude drug name

Market name竜胆
Formal name竜胆
Japanese nameりゅうたん, Ryūtan
Vernacular nameLongdan
Latin nameGentianae Scabrae Radix (JP), Gentianae Radix et Rhizoma (CP)
English nameJapanese Gentian (JP), Chinese Gentian (CP)
Original plant nameGentiana scabra Bge.1, Gentiana manshurica Kitag. or Gentiana triflora Pall., (Tōrindō1)
Family nameGentianaceae
Used partClassificationPlant origin
Sub classification root + rhizome
Production area informationPeople's Republic of China, Liaoning Prov.
Collection informationJapan, Osaka Pref., Tochimoto Tenkaido Co., Ltd.
Collection date2020/07/03
CollectorKatsuko Komatsu
RemarksJoint Usage / Research Center Project 2020
TMPW No.30697

The capital city, provincial capital city or the representative  
location of its administrative area is indicated.  
41.805699
123.43147199999999
Production area information
People's Republic of China,Liaoning Prov.
https://ethmed.toyama-wakan.net/img/pin_san.png
34.6937378
135.50216509999996
Collection information
Japan,Osaka Pref.
https://ethmed.toyama-wakan.net/img/pin_nyu.png

Scientific information data base

Common name竜胆, Longdan, Gentianae Scabrae Radix (JP18), Gentianae Radix et Rhizoma (CP2020), Japanese Gentian (JP18), Chinese Gentian (CP2020)
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Original plant nameGentiana scabra Bunge1, Gentiana manshurica Kitagawa, Gentiana triflora Pallas, and etc. (Tōrindō1)
original plant image
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Family nameGentianaceae
Used partroot and rhizome
Quality for selectionGood Longdan is large, pale yellowish-brown and has many fibrous roots. (TN)
Official compendiumJP XVIII, CP (2020 ed.)
Clinical applicationAs a bitter stomachic, it is used just like Gentian (the root and rhizome of Gentiana lutea L.) . In Kampo, as an anti-inflammatiory, it is applied to treat congestion of digestive organs, inflammation, urethriris, and rheumatoid.
Medical systemTraditional Chinese medicine
Drug effect in
traditional medicine
Traditional
classification
Drugs for elimination heat and dampness
Beneficial effect[Property and Flavor] Cold; bitter.
[Meridian Tropism] Liver and gallbladder meridians.
[Actions] To clear heat and dry dampness, purge liver-gallbladder fire.
[Indications] Dampness-heat jaundice, pudendal swelling and itching, vaginal discharge, itching caused by eczema, red eyes caused by liver fire, tinnitus and deafness, hypochondriac pain and bitter taste in the mouth, persistent erection, convulsions.
Chemical constituentOligosaccharides
(*C1):
Gentianose, Gentiobiose

Monoterpenoids
(*C1):
Gentiopicrin, Swertiamarin, Gentianine
G. triflora var. japonica (*C1):
Trifloroside

Xanthones
(*C1):
Gentisin

Other aromatic derivatives
(*C1):
Gentisic acid

Chemical structure






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Pharmacological effectenhanced gastric juices secretion (extract), immunosuppression (mild).
DNA sequenceAJ294588, AJ294648; Traditioal Medical & Parmaceutical Database.
Classical reference
(Chinese Herbal Classic "Zhenglei bencao")
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DiseaseJaundice, Dysuria, Urodynia, Cloudy urine, Scrotal swelling, Itching of the genital, Leukorrhea, Red eye, Eye pain, Chest pain, Pain of lateral sides of trunk, Deafness, Swelling and pain of the ear, High fever, Convulsion
FormulationJokinritsuansan, Sokeikakketsuto, Rikkosan, Ryutan-shakan-to, Ryutan-shakan-to, Kumisaikoto
Related drugsGentianae Radix (the root and rhizome of Gentiana lutea L.), Gentianae Macrophyllae Radix (the root of Gentiana macrophylla Pall., G. straminea Maxim., G. crassicaulis Duthie ex Burkill or G. dahurica Fisch.)
ReferencesJP18: The 18th edition of the Japanese Pharmacopoeia.
CP2020: Pharmacopoeia of the People's Republic of China 2020 edi.
C1)The Encyclopedia of Wakan-Yaku with Color Pictures Vol. I, pp 166-167.
RemarksGuan-longdan (関龍胆), produced in the Northeast provinces of China, contains the subterranean part of G. triflora Pall., as a fraction. The original plant of "Yunnan-longdan" (雲南龍胆) and "Guizhou-longdan" (貴州龍胆) (produced in Yunnan, Guizhou, Sichuan Prov.) are G. regescens Fr. and the part used is the subterranean part.
In the past, Japanese "Karahuto-ryūtan" (樺太龍胆) or "Ezo-ryūtan" (蝦夷龍胆) was available in the market, which was the subterranean part of G. triflora Pallas var. japonica Hara (Ezo-rindō in Jap.), but it has no marketability now.
Last renewal date2021/09/27