Crude drug sample data base

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Crude drug name

Market name苦参
Formal name苦参
Japanese nameくじん, Kujin
Vernacular nameKushen
Latin nameSophorae Radix (JP), Sophorae Radix (CP)
English nameSophora Root (JP), Lightyellow Sophora Root (CP)
Used partClassificationPlant origin
Sub classification root
Production area informationPeople's Republic of China, Chengde
Collection informationJapan(ToS), Osaka Pref., Tochimoto Tenkaido Co., Ltd. [Non-commercial Sample]
Collection date2021/04/01
CollectorKatsuko Komatsu
TMPW No.30949

The capital city, provincial capital city or the representative  
location of its administrative area is indicated.  
40.952942
117.96275000000003
Production area information
People's Republic of China,Chengde
https://ethmed.toyama-wakan.net/img/pin_san.png
34.6937249
135.5022535
Collection information
Japan(ToS),Osaka Pref.
https://ethmed.toyama-wakan.net/img/pin_nyu.png

Scientific information data base

Common name苦参, Kushen, Sophorae Radix (JP18), Sophorae Flavescentis Radix (CP2020), Sophora Root (JP18), Lightyellow Sophora Root (CP2020)
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Original plant nameSophora flavescens Aiton, (Kurara)
original plant image
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Family nameLeguminosae
Used partroot (often without periderm)
Quality for selectionGood Kushen is long and has less twists and turns. The inside is yellow. It has a strong bitter taste. (TN)
Official compendiumJP XVIII, CP (2020 ed.)
Clinical applicationAs an amaroid stomachic, antifebrile, diuretic, antiinflammatory drug, antidiarrheal, for normalizing function of the gall bladder, Kushen is applied for skin disease due to blood heat in limbs, stomatitis, bacterial diarrhea, inflammation of the intestines and oliguria. It is used for eczema and parasitic skin disease externally.
Medical systemTraditional Chinese medicine
Drug effect in
traditional medicine
Traditional
classification
Drugs for elimination heat and dampness
Beneficial effect[Property and Flavor] Cold; bitter.
[Meridian Tropism] Heart, stomach, large intestine and bladder meridians.
[Actions] To clear heat and dry dampness, kill worms, disinhibit urine.
[Indications] Heat dysentery, bloody stool, jaundice with annuria, red or white vaginal discharge, pudendal swelling and itch, eczema, dampness sore, itching of skin, scabies and tinea leprosy; Topical application, trichomonas vaginitis.
Chemical constituentSterols
(*C1):
beta-Sitosterol, Stigmasterol, Campesterol

Flavanones & Dihydroflavonols
(*C2):
Kurarinol, Kurarinone, Kuraridinol, Norkurarinol

Isoflavones
(*C1):
Trifolirhizin

Alkaloids
(*C1):
Matrine, Oxymatrine, Sophoranol, Anagyrine, Methylcytisine, Baptifoline, Sophocarpine, Isomatrine

Chemical structure




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Pharmacological effectSuppression of the stress ulcer (matrine fraction, oxymatrine fraction). Autokinetic disorder, suppression of the vasomotor center (matrine). Antifungal (decoction: various type of cutaneous Trichophyton).
DNA sequenceAF123452; Traditioal Medical & Parmaceutical Database.
Classical reference
(Chinese Herbal Classic "Zhenglei bencao")
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DiseaseDiarrhea, Hematochezia, Bleeding hemorrhoids, Jaundice, Itching, Leukorrhea, Oliguria
FormulationSammotsuogonto, Shofusan, Tokinentsuto, Tokibaimokujingan
ReferencesJP18: The 18th edition of the Japanese Pharmacopoeia.
CP2020: Pharmacopoeia of the People's Republic of China 2020 edi.
C1) The Encyclopedia of Wakan-Yaku with Color Pictures Vol. I, p 106.
C2) Outline of Pharmacognosy, a Textbook, p 287.
RemarksIt is used as an ingredient for domestic medicine.
Last renewal date2023/11/24