Crude drug sample data base

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Crude drug name

Market name霊芝
Formal name霊芝
Japanese nameれいし, Reishi
Vernacular nameLingzhi
Latin nameGanoderma (CP)
English nameGlossy Ganoderma (CP)
Used partClassificationPlant origin
Sub classification fruit body
Production area informationPeople's Republic of China
Collection informationJapan(ToS), Osaka Pref., Tochimoto Tenkaido Co., Ltd. [Non-commercial Sample]
Collection date2021/04/01
CollectorKatsuko Komatsu
TMPW No.31064

The capital city, provincial capital city or the representative  
location of its administrative area is indicated.  
Production area information
People's Republic of China
https://ethmed.toyama-wakan.net/img/pin_san.png
34.6937249
135.5022535
Collection information
Japan(ToS),Osaka Pref.
https://ethmed.toyama-wakan.net/img/pin_nyu.png

Scientific information data base

Common name霊芝, Lingzhi, Ganoderma (CP2020), Glossy Ganoderma (CP2020)
Synonyms紫芝 (Zizhi), 赤芝 (Chizhi)
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Original plant nameGanoderma lucidum (Leyss. ex Fr.) Karst., (Mannentake)
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Family namePolyporaceae
Used partfruit body
Quality for selectionGood Lingzhi is purplish red and wholly lustered. (TN)
Official compendiumCP (2020 ed.)
Clinical applicationAs a tonic and sedative, Lingzhi is applied to treat nervous breakdown, insomnia, indigestion, chronic diseases such as cough due to senile bronchitis, etc. In Japan, as folk medicine, it is applied to treat hyperlipemia, angina pectoris, arrhythmia, hepatitis, peptic ulcer, and diabetes mellitus. The applications for the anticancer drug has been developed.
Medical systemTraditional Chinese medicine
Drug effect in
traditional medicine
Traditional
classification
Sedatives and tranquilizer
Beneficial effect[Property and Flavor] Neutral; sweet.
[Meridian Tropism] Heart, lung, liver and kidney meridians.
[Actions] To tonify qi to tranquilize the mind, suppress cough and relieve panting.
[Indications] Disquietude heart spirit, insomnia and palpitation, cough and panting caused by lung deficiency, consumptive disease with shortness of breath, no desire for food and drink.
Chemical constituentFatty acids
(*C1):
Mylistic acid, Pentadecanoic acid, Palmitic acid, Linolenic acid, Oleic acid, Stearic acid

Monosaccharides
(*C1):
Mannitol

Polysaccharides
(*C1):
Fucofructoglucan, Peptideglucan, Arabinoxyloglucan, Xylogalactoglucan, beta-D-Glucan, Ganoderan A, Ganoderan B, Ganoderan C

Triterpenoids
(*C1):
Ganoderic acid A, Ganoderic acid B, Ganoderic acid C1, Ganoderic acid C2, Ganoderic acid D, Ganoderic acid E, Ganoderic acid F, Ganoderic acid G, Ganoderic acid H, Ganoderic acid I, Ganoderic acid J, Ganoderic acid K, Ganoderic acid L, Ganoderic acid Ma, Ganoderic acid Mb, Ganoderic acid Mc, Ganoderic acid Md, Ganoderic acid Me, Ganoderic acid Mf, Ganoderic acid Mg, Ganoderic acid Mh, Ganoderic acid Mi, Ganoderic acid Mj, Ganoderic acid R, Ganoderic acid S, Ganoderic acid S1, Ganoderic acid T, Ganoderic acid U, Ganoderic acid V, Ganoderic acid W, Ganoderic acid X, Ganoderic acid Y, Ganoderic acid Z, Lucidenic acid A, Lucidenic acid B, Lucidenic acid C, Lucidenic acid D1, Lucidenic acid D2, Lucidenic acid E1, Lucidenic acid E2, Lucidenic acid F, Lucidenic acid G, Ganolucidenic acid A, Ganolucidenic acid B, Ganoderiol A, Ganoderiol B, Ganodermanontriol, Ganodermatriol, Ganoderenic acid A, Ganoderenic acid B, Ganoderenic acid C, Ganoderenic acid D, Ganoderal A, Ganoderol A, Ganoderol B, Lucidone A, Lucidone B, Lucidone C, Compound B8, Compound B9, Compound C6
G. lucidum (*C2,C3,C4,C5,C6,C7):
3beta,12beta-Dihydroxy-7,15,23-trioxo-5alpha-lanost-8-en-26-oic acid, 7alpha,15alpha-Dihydroxy-3,11,23-trioxo-5alpha-lanost-8-en-26-oic acid, Ganoderic acid C2, Ganoderic acid D, Ganoderic acid E, Ganoderic acid F, Ganoderic acid G, Ganoderic acid H, Ganoderic acid I, Ganoderic acid K, Ganolucidic acid A, Ganolucidic acid B, 25-Hydroxy-3-epidehydrotumulosic acid, Lucidenic acid D2, Lucidenic acid E2, Lucidenic acid F, 3beta,7alpha,15alpha-Trihydroxy-11,23-dioxo-5alpha-lanost-8-en-26-oic acid

Chemical structure







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Pharmacological effectSuppression of the central nervous system, antitussive, expectorant (ethanol extract, water soluble extract), antihypertension (peptidoglycan), antitumor (glycans), decrease in blood sugar (ganoderan A, B, C), antiandrogen (ethanol extract), natural killer (NK) cell activation (hot-water extract).
DNA sequenceAF044274, AF044490, AF079584, AF110726, AF170007, AF170008
Classical reference
(Chinese Herbal Classic "Zhenglei bencao")
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DiseaseNeurasthenia, Insomnia, Dyspepsia, Chronic bronchitis, Hyperlipidemia, Angina pectoris, Arrhythmia, Gastric ulcer, Viral hepatitis, Enterocolitis, Diabetes mellitus, Cancer
Formulation
ReferencesCP2020: Pharmacopoeia of the People's Republic of China 2020 edi.
C1)The Encyclopedia of Wakan-Yaku with Color Pictures Vol. II, pp 247-250.
C2)Chem.Pharm.Bull.,34,4018(1986).
C3)Chem.Pharm.Bull.,34,3695(1986).
C4)Chem.Pharm.Bull.,33,2624(1985).
C5)Chem.Pharm.Bull.,33,2628(1985).
C6)Chem.Pharm.Bull.,34,4030(1986).
C7)Phytochemistry,39,1165(1995).
Last renewal date2021/09/28