Crude drug sample data base

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Crude drug name

Market nameセンキュウ [NIB-64]
Formal name川芎
Japanese nameせんきゅう, Senkyū
Vernacular nameSenkyū
Latin nameCnidii Rhizoma (JP)
English nameCnidium Rhizome (JP)
Original plant nameCnidium officinale Makino, (Senkyū)
Family nameUmbelliferae
Used partClassificationPlant origin
Sub classification rhizome
Production area informationJapan, Hokkaido Pref.
Collection informationJapan, Ibaraki Pref., National Institutes of Biomedical Innovation, Health and Nutrition
Collection date2022/07/26
CollectorKatsuko Komatsu
Remarks[NIB-64]
TMPW No.31545

The capital city, provincial capital city or the representative  
location of its administrative area is indicated.  
43.0620958
141.3543763
Production area information
Japan,Hokkaido Pref.
https://ethmed.toyama-wakan.net/img/pin_san.png
36.3418112
140.4467935
Collection information
Japan,Ibaraki Pref.
https://ethmed.toyama-wakan.net/img/pin_nyu.png

Scientific information data base

Common name川芎, Chuanxiong, Cnidii Rhizoma (JP18), Chuanxiong Rhizoma (CP2020), Cnidium Rhizome (JP18), Szechwan Lovage Rhizome (CP2020)
Synonyms仙台川芎
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Original plant nameCnidium officinale Makino1, Ligusticum chuanxiong Hortorum2, (JP products: Senkyū1, CN products2)
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Family nameUmbelliferae
Used partrhizome
Quality for selectionThe cortex of good Chuanxiong is dark brown and the inside is pale yellow. It is large and has a intense pungency. (NI)
Official compendiumJP XVIII, CP (2020 ed.)
Clinical applicationFor tonifying the blood and removing blood stasis, as a tonic, tranquilizer, painkiller, chuanxiong is applied for poor circulation, anemia and dysmenorrhea.
Medical systemTraditional Chinese medicine
Drug effect in
traditional medicine
Traditional
classification
Drugs for invigorating blood circulation
Beneficial effect[Property and Flavor] Warm; pungent.
[Meridian Tropism] Liver, gallbladder and pericardium.
[Actions] To activate blood, move qi, dispel wind, and relieve pain.
[Indications] Chest impediment with heart pain, stabbing pain in the chest and the hypochondrium, swelling and pain caused by traumatic injuries, menstrual irregularities, amenorrhea and dysmenorrhea, abdominal pain and masses, headache, painful impediment caused by wind-dampness.
Chemical constituentPhenylpropanoids
L. chuanxiong (*C1):
Ferulic acid
C. officinale (*C1):
Coniferyl ferulate, Ferulic acid

Phthalides
L. chuanxiong (*C1):
3-Butylidene-7-hydroxyphthalide, cis-6,7-Dihydroxyligustilide, trans-6,7- Dihydroxyligustilide, Wallichilide, Butylphthalide, Butylidenephtalide, Ligustilide, Senkyunolide A, Neocnidilide
C. officinale (*C1):
Cnidilide, Ligustilide, Neocnidilide, Butylphtalide, Sedanonic acid anhydride, Senkyunolide A, Senkyunolide B, Senkyunolide C, Senkyunolide D, Senkyunolide E, Senkyunolide F, Senkyunolide G, Senkyunolide H, Senkyunolide I, Senkyunolide J

Phenol derivatives
C. officinale (*C1):
Vanillin

Alkaloids
L. chuanxiong (*C1):
油状のアルカロイド [oily alkaloids]

Other nitrogen compounds
L. chuanxiong (*C1):
Tetramethylpyrazine
C. officinale (*C1):
Tetramethylpyrazine

Chemical structure



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Pharmacological effectSedative (water extract,ether extract).Estrous enhancement (extract).Mucocutaneous stimulation(the oil of Cnidii Rhizoma:external use).Effects on vasomotor center and respiratory center (the oil of Cnidii Rhizoma, produced in China:low doses;excitation, high doses;suppression).Central relaxation of the muscles,relaxation of the smooth muscles(ligustilide).
DNA sequenceD83027, D44586, D83028, D44572, U78388, U78448
Classical reference
(Chinese Herbal Classic "Zhenglei bencao")
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DiseaseIrregular menstruation, Menorrhalgia, Amenorrhea, Dystocia, Retained placenta, Chest pain, Pain of lateral sides of trunk, Anginal pain, Pyogenic dermatosis, Swelling and pain due to contusion, Headache, Swelling and pain of joint
FormulationIfuto, Uyakujunkisan, Unkeito, Unseiin, Ekkiyoeito, Kagawagedokuzai, Kagenhachimotsuto, Katsuketsugedokuto, Katsuketsusan'oto, Kakkontokashin'isenkyuto, Kamishimotsuto, Kamishoyosangoshimotsuto, Kamihassento, Kikyogedokuto, Kibanto, Gyakubanto, Kyukikyogaito, Kyukichoketsuin, Kyukihochuto, Kyoseihatekigan, Kufushokutsuto, Keigairengyoto, Keigairengyoto, Kokikososan, Kokyuto, Kokonrokukenzokumeito, Goshakusan, Gomotsudaioto, Saikoshimotsuto, Saikoseikansan, Saikosokanto, Sansoninto, Shikonboreito, Jijintsujito, Jijinmeimokuto (Jinkimeimouto), Shisowakiin, Shichimotsukokato, Shimotsuto, Shimotsutokakibansetsuketsumei, Shimotsutokakkekagen, Shaito, Juzentaihoto, Jumizasan, Jumihaidokuto, Jurokumiryukiin, Junhaito, Shozokumeito, Jokinritsuansan, Shin'isan, Jinkimeimokuto, Seijokentsuto, Seijobofuto, Seineitsugeutsuto, Seinetsuhoketsuto, Sesshoin, Senkanmeimokuto, Senkyuchachosan, Zokumeito, Sokeikakketsuto, Daizokumeito, Daibyakuchuin, Daibofuto, Jidabokuippo, Jizusoippo, Chimobukuryoto, Choreitogoshimotsuto, Tokiinshi, Tokisan, Tokishakuyakusanmatsu, Tokishakuyakusanryo, Tokiyoketsuto, Dokkatsukiseito, Naitaku-san, Naitaku-san, Nyoshinsan, Haidokuto, Hachimitaikaho, Hachimotsuto, Hacchinto, Bofutsushosan, Hojinto, Botanpisan, Hontonto, Hontonto, Hontonbukuryoto, Yokukansan, Yokukansankachinpihangeto, Yokukansankachinpihangeto, Ryutan-shakan-to, Reiyoukakuin, Rengyoto, Rengyoto, Renjuin, Rokuutsuto
ReferencesJP18: The 18th edition of the Japanese Pharmacopoeia.
CP2020: Pharmacopoeia of the People's Republic of China 2020 edi.
C1) The Encyclopedia of Wakan-Yaku with Color Pictures Vol. I, pp 23-24.
RemarksThe Japanese Pharmacopoeia defines it as the rhizome of C. officinale.
Last renewal date2021/09/27