Crude drug sample data base

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Crude drug name

Market nameオンジ [NIB-491]
Formal name遠志
Japanese nameおんじ, Onji
Vernacular nameYuanzhi
Latin namePolygalae Radix (JP), (CP)
English namePolygala Root (JP), Thinleaf Milkwort Root (CP)
Original plant namePolygala sp.
Family namePolygalaceae
Used partClassificationPlant origin
Sub classification root
Production area informationPeople's Republic of China, Shaanxi Prov.
Collection informationJapan, Ibaraki Pref., National Institutes of Biomedical Innovation, Health and Nutrition
Collection date2022/07/26
CollectorKatsuko Komatsu
Remarks[NIB-491]
TMPW No.31649

The capital city, provincial capital city or the representative　　
location of its administrative area is indicated.　　
34.341574
108.93976999999995
Production area information
People's Republic of China,Shaanxi Prov.
https://ethmed.toyama-wakan.net/img/pin_san.png
36.3418112
140.4467935
Collection information
Japan,Ibaraki Pref.
https://ethmed.toyama-wakan.net/img/pin_nyu.png

Scientific information data base

Common name遠志, Yuanzhi, Polygalae Radix (JP18, CP2020), Polygala Root (JP18), Thinleaf Milkwort Root (CP2020)
Synonyms大遠志，志通
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Original plant namePolygala tenuifolia Willdenow (rarely Polygala sibirica Linn. ）, (Itohimehagi)
original plant image
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Family namePolygalaceae
Used partroot or root bark
Quality for selectionGood Yuanzhi is enlarged, thick and has irregular surface. Neither thin nor stiff one is good. (TN)
Official compendiumJP XVIII, CP (2020 ed.)
Clinical applicationAs a tranquilizer, expectorant and tonic, Yuanzhi is applied for forgetfulness, dream-disturbed sleep, cough, phlegm-heat and carbuncles.
Medical systemTraditional Chinese medicine
Drug effect in
traditional medicine		Traditional
classification		Sedatives and tranquilizer
Beneficial effect[Property and Flavor] Warm; bitter and pungent.
[Meridian Tropism] Heart, kidney and lung meridians.
[Actions] To tranquilize the mind and replenish wisdom, coordinate the heart and kidney, dispel phlegm, and disperse swelling.
[Indications] Insomnia and dream-disturbed sleep, forgetfulness and fright palpitations caused by heart-kidney non-interaction pattern; absentmindedness, ungratifying expectoration of phlegm, sore and ulcer, swelling and toxin, breast swelling and pain.
Chemical constituentMonosaccharides
(*C1):
Polygalitol

Triterpenoids
(*C1):
beta-Amyrin

Triterpenoid saponins
(*C1):
Onjisaponin A(=Senegin IV), Onjisaponin B(=Senegin III), Onjisaponin C, Onjisaponin D, Onjisaponin E, Onjisaponin F, Onjisaponin G

Phenylpropanoids
(*C1):
3,4,5-Trimethoxycinnamic acid

Xanthones
(*C1):
3-Hydroxy-2,6,7,8-tetramethoxyxanthone, 2,6,7,8-Tetramethoxyxanthone, 2,3,6,7,8-Pentamethoxyxanthone

Flavanones & Dihydroflavonols
(*C1):
Onsitin

Chemical structure



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Pharmacological effectInhibition of phosphodiesterase （onjisaponin B，E，F)，central nervous system inhibition （onjisaponin F).
DNA sequenceU42797, L01945
Classical reference
(Chinese Herbal Classic "Zhenglei bencao")		※Click this image to see the actual image
DiseasePalpitation, Insomnia, Amnesia, Dementia, Cough, A lot of sputum, Pyogenic dermatosis
FormulationKamiuntanto, Kamikihito, Kihito, Shoshinto, Ninjin-yoei-to, Ryukotsuto
Related drugsSenegae Radix
ReferencesJP18: The 18th edition of the Japanese Pharmacopoeia.
CP2020: Pharmacopoeia of the People's Republic of China 2020 edi.
C1)The Encyclopedia of Wakan-Yaku with Color Pictures Vol. I, pp 173-174.
RemarksThe root bark without woody parts is called Yuanzhirou (遠志肉), Zhitong (志通) or Yuanzhitong (遠志筒), and considered to be superior in quality.
Last renewal date2021/09/27
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