Crude drug sample data base

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Crude drug name

Market nameゴミシ [NIB-270]
Formal name五味子
Japanese nameごみし, Gomishi
Vernacular nameWuweizi
Latin nameSchisandrae Fructus (JP), Schisandrae Chinensis Fructus (CP)
English nameSchisandra Fruit (JP), Chinese Magnoliavine Fruit (CP)
Other names北五味子
Original plant nameSchisandra sp.
Family nameSchisandraceae
Used partClassificationPlant origin
Sub classification mature fruit
Production area informationPeople's Republic of China, Heilongjiang Prov.
Collection informationJapan, Ibaraki Pref., National Institutes of Biomedical Innovation, Health and Nutrition
Collection date2022/07/26
CollectorKatsuko Komatsu
Remarks [NIB-270]
TMPW No.31672

The capital city, provincial capital city or the representative  
location of its administrative area is indicated.  
45.80377499999999
126.53496700000005
Production area information
People's Republic of China,Heilongjiang Prov.
https://ethmed.toyama-wakan.net/img/pin_san.png
36.3418112
140.4467935
Collection information
Japan,Ibaraki Pref.
https://ethmed.toyama-wakan.net/img/pin_nyu.png

Scientific information data base

Common name五味子, Wuweizi, Schisandrae Fructus (JP18), Schisandrae Chinensis Fructus (CP2020), Schisandra Fruit (JP18), Chinese Magnoliavine Fruit (CP2020)
Synonyms北五味子 Baiwuweizi
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Original plant nameSchisandra chinensis Baillon, (Chōsengomishi)
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Family nameSchisandraceae
Used partmature fruit
Quality for selectionGood Wuweizi is deep purple and has wrinkles on the surface. It tastes sweet. (TN)
Official compendiumJP XVIII, CP (2020 ed.)
Clinical applicationAs an antibechic, astringent, antidiarrheal and tonic, wuweizi is applied for hepatic disorder and the diseases with thirst, cough, diarrhea and phlegm.
Medical systemTraditional Chinese medicine
Drug effect in
traditional medicine
Traditional
classification
Astringents and haemostatics
Beneficial effect[Property and Flavor] Warm; sour and sweet.
[Meridian Tropism] Lung, heart and kidney meridians.
[Actions] To astringe and secure, tonify qi, engender fluid, tonify the kidney and calm the heart.
[Indications] Chronic cough, dyspnea of deficiency type, dream emission, spermatorrhea, enuresis, frequent urination, chronic diarrhea, spontaneous sweating, night sweat, thirst caused by fluid consumption, interior heat wasting-thirst, palpitations and insomnia.
Chemical constituentOther aliphatic and related compounds
(*C1):
Fumaric acid, Citric acid, Malric acid, Tartaric acid

Monoterpenoids
(*C1):
Citral

Sesquiterpenoids
(*C1):
Sesquicarene, alpha-Ylangene, alpha-Chamigrene, beta-Chamigrene, Chamigrenal

Sterols
(*C1):
beta-Sitosterol

Lignans & Neolignans
(*C1):
Schizandrin (= Schizandrol A), Gomisin A (= Schizandrol B), Gomisin B, Gomisin C, Gomisin D, Gomisin E, Gomisin F, Gomisin G, Schizandrin A (= Deoxyschizandrin), Schizandrin B, Schizandrin C, Schizandrel A, Schizandrel B
(*C2):
Pregomisin

Chemical structure






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Pharmacological effectSuppression of gastric juice secretion,stimulation of bile secretion (schizandrin).sedative・analgesic,decreases body temperature,relaxation of muscles,suppression of stress-induced ulcer (schizandrin, gomisin A).Antitussive (gomisin A).Ataxia,induction of spasm,appearance of arousal brain wave (coal oil-ether extract).
DNA sequenceAF163710, AF094561, AF238061, AF263441, L75842; Traditioal Medical & Parmaceutical Database.
Classical reference
(Chinese Herbal Classic "Zhenglei bencao")
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DiseaseCough, Dyspnea, Spontaneous sweating, Night sweats, Frequent urination, Incontinence of urine, Diarrhea, Thirst, Malaise, Lack of energy, Palpitation
FormulationKamishimotsuto, Kyukihochuto, Kyososan, Kobokumaoto, Shionsan, Shoseiryuto, Shoseiryukasekkoto, Shoseiryugomakyokansekito, Shomyakusan, Joshitsuhokito, Seishoekkito, Seinetsuhokito, Seinetsuhoketsuto, Seihaito, Chimobukuryoto, Ninjin-yoei-to, Ninjin-yoei-to, Baimoto, Bakumondoinshi, Fuhishomyakusankabyakukyu, Hohaito, Mibakuekkito, Yakammaoto, Yohaito, Ryokankyomishingeto, Ryokankyomishingeninto, Ryokankyomishingeninoto, Ryokangomikyoshinto
Related drugsNanwuweizi (see "Remarks")
ReferencesJP18: The 18th edition of the Japanese Pharmacopoeia.
CP2020: Pharmacopoeia of the People's Republic of China 2020 edi.
C1)The Encyclopedia of Wakan-Yaku with Color Pictures Vol. I, pp 201-204.
RemarksIn China, the fruit of Schisandra sphenanthera Rehd. et Wils. is called "Nanwuweizi". It is used similarly to the fruit of S. chinensis (Beiwuweizi). The Pharmacopoeia of People's Republic of China defines Wuweizi as these two species.
Last renewal date2021/09/27