Crude drug sample data base

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Crude drug name

Market name黄連
Formal name黄連
Japanese nameおうれん, Ōren
Vernacular nameHuanglian
Latin nameCoptidis Rhizoma (JP), (CP)
English nameCoptis Rhizome (JP), Golden Thread (CP)
Grade1 st
Original plant nameCoptis chinensis Franch., or other species of the same genus
Family nameRanunculaceae
Used partClassificationPlant origin
Sub classification rhizome
Production area informationPeople's Republic of China, Chongqing City
Collection informationJapan(ToS), Osaka Pref., Tochimoto Tenkaido Co., Ltd. [Non-commercial Sample]
Collection date2023/06/07
CollectorKatsuko Komatsu
TMPW No.31742

The capital city, provincial capital city or the representative  
location of its administrative area is indicated.  
29.4315861
106.91225099999997
Production area information
People's Republic of China,Chongqing City
https://ethmed.toyama-wakan.net/img/pin_san.png
34.6937249
135.5022535
Collection information
Japan(ToS),Osaka Pref.
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Scientific information data base

Common name黄連, Huanglian, Coptidis Rhizoma (JP18, CP2020), Coptis Rhizome (JP18), Golden Thread (CP2020)
Synonyms丹波黄連, 越前黄連, 因州黄連, 味連, 雅連
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Original plant nameCoptis japonica Makino1, Coptis chinensis Franchet, Coptis deltoidea C.Y. Cheng et Hsiao or Coptis teeta Wallich, (Oren1)
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Family nameRanunculaceae
Used partrhizome without root
Quality for selectionGood Huanglian, which is deep yellow inside, is thick, firm and has a strong bitter taste. "Maohuanglian" has fibrous roots and less bitterness. It is lower quality. (TN)
Official compendiumJP XVIII, CP (2020 ed.)
Clinical applicationAs an antiphlogistic amaroid stomachic and tranquilizer, huanglian is applied for palpitation, mental instability, stuffiness of epigastrium, vomiting, diarrhea, stomachache and bleeding, accompanied with congestion or inflammation.
Medical systemTraditional Chinese medicine
Drug effect in
traditional medicine
Traditional
classification
Drugs for elimination heat and dampness
Beneficial effect[Property and Flavor] Cold; bitter.
[Meridian Tropism] Heart, spleen, stomach, liver, gallbladder and large intestine meridians.
[Actions] To clear heat, dry dampness, purge fire and remove toxin.
[Indications] Dampness-heat stuffiness and fullness, vomiting, acid reflux, diarrhea and dysentery, jaundice, high fever with loss of consciousness, intense heart fire, insomnia caused by vexation, palpitations, blood heat with hematemesis, red eyes, toothache, wasting-thirst, swelling abscess, deep-rooted boil and sore;
topically for eczema, dampness sore, purulent discharge from the ear.
Chemical constituentPhenylpropanoids
(*C1):
Ferulic acid

Isoquinoline alkaloids
(*C1):
Berberine, Palmatine, Jateorrhizine, Coptisine, Magnoflorine, Tetrahydropalmatine, Tetrahydroberberine, Worenine

Chemical structure



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Pharmacological effectAntibacterial (broad antibacterial spectrum of berberine),constipation (berberine).
DNA sequenceL75838, AF093730; Traditioal Medical & Parmaceutical Database.
Classical reference
(Chinese Herbal Classic "Zhenglei bencao")
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DiseaseDiarrhea, Full stomach, Vomitting, Feeling of pressure in the chest, Thirst, Oliguria, High fever, Disturbance of consciousness, Hematemesis, Nasal hemorrhage, Fret, Insomnia, Stomatitis, Toothache, Bleeding from root of tooth, Stomachache, Red eye, Swelling and pain of the throat, Pyogenic dermatosis, Tympanitis, Eye pain
FormulationAnzanto, Ireito, Inchinsan, Unseiin, Ogesan, Orento, Oren'akyoto, Orengedokuto, Orengedokuto, Orenshodokuin, Kagenryokakusan, Kakkon'oren'ogonto, Kakkonkokato, Kamisaikakujioto, Kamishimotsuto, Kamishokankyoto, Kankyoto, Kankyooren'ogon'ninjinto, Kanzoshashinto, Kanrento, Kanrendaioto, Kanrendaiokasekkoto, Keigairengyoto, Keigairengyoto, Kowashakuyakuto, Saikanto, Saikoseikansan, San'oshashinto, San'oshashinto (brewing), Jijinmeimokuto (Jinkimeimouto), Shaito, Shakuyakuto, Junkiwachuto, Shokankyoto, Shokanto, Shokyoshashinto, Shosaikotokaorenbukuryo, Shobaishashinto, Shohito, Jinkimeimokuto, Jinrento, Seiishakato, Seiinrikakuto, Seikanto, Seijobofuto, Seishinto, Seichuankaito, Seineitsugeutsuto, Seiryoin, Senkanmeimokuto, Daibyakuchuin, Danrito, Chikujountanto, Jishusabiho, Jizutsuippo, Chushaen, Chuseito, Tokiyoketsuto, Tokirokuoto, Naisoorento, Nyoshinsan, Hakutooto, Hakutookakanzoakyoto, Hangeshashinto, Bukuryhoshinto, Fushinto, Honposhakuyakuto, Meiroin, Ryutan-shakan-to, Rogyokuto, Kaishun'inchinsan
Related drugsMaweilian (see "Remarks")
ReferencesJP18: The 18th edition of the Japanese Pharmacopoeia.
CP2020: Pharmacopoeia of the People's Republic of China 2020 edi.
C1) The Encyclopedia of Wakan-Yaku with Color Pictures Vol. I, pp 154-158.
RemarksChinese "Weilian" is the rhizome of C. chinensis, "Yalian" is that of C. deltoidea C.Y.Cheng et Hsiao, "Emeiyelian" is that of C. omeiensis (Cheng) C.Y.Cheng, "Yunlian" is that of C. teeta Wall. Chinese "Mawielian" is the subterranean part of Thalictrum species of family Ranunculaceae.
Last renewal date2023/07/21