Crude drug sample data base

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Crude drug name

Market name蛇床子
Formal name蛇床子
Japanese nameじゃしょうし, Jashōshi
Vernacular nameShechuangzi
Latin nameCnidii Monnieri Fructus (JP), Cnidii Fructus (CP)
English nameCommon Cnidium Fruit (JP), (CP)
Original plant nameCnidium monnieri (L.) Cuss., (Okazeri)
Family nameUmbelliferae
Used partClassificationPlant origin
Sub classification mature fruit
Collection informationTaiwan, Chun Yuan Hang
Collection date1966/10/04
TMPW No.3758

Scientific information data base

Common name蛇床子, Shechuangzi, Cnidii Monnieri Fructus (JP18), Cnidii Fructus (CP2020), Cnidium Monnieri Fruit (JP18), Common Cnidium Fruit (CP2020)
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Original plant nameCnidium monnieri Cusson1, Torilis japonica (Houtt.) De Candolle2, (CN products: Okazeri1, JP&KR products: Yabujirami2)
original plant image
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Family nameUmbelliferae
Used partmature fruit
Quality for selectionThe external surface of good Shechuangzi is yellow-green in color. When it is kneaded by hands, it gives acrid odor strongly. (TN)
Official compendiumJHMC (1989), JP XVIII, CP (2020 ed.)
Clinical applicationShechuangzi is an important drug for yin disease of women. As an astringent-antiphlogistic drug, it is applied externally for vulval itching, eczema of scrotum and other eczemas. It is also used for impotence as internally.
Medical systemTraditional Chinese medicine
Drug effect in
traditional medicine
Traditional
classification
External drugs
Beneficial effect[Property and Flavor] Warm; pungent, bitter; slightly toxic.
[Meridian Tropism] Kidney meridian.
[Actions] To dry dampness and dispel wind, kill worms to relieve itching, warm the kidney and invigorate yang.
[Indications] Pudendal itch, vaginal discharge, itching caused by eczema, fixed impediment lumbago, impotence caused by kidney deficiency, infertility caused by uterine coldness.
Chemical constituentFatty acids
T. japonica (*C1): 脂肪油約 / fatty oil about 10%
Petroselinic acid, Myristine, Olein

Monoterpenoids
C. monnieri (*C1): 精油約 / essential oil about 1.3%
l-Pinene, l-Camphene, Bornyl isovalerate

Sesquiterpenoids
T. japonica (*C1): 精油約 / essential oil about 1.4%
alpha-Cadinene, Torilin

Coumarins
C. monnieri (*C1):
Columbianadin, O-Acetylcolumbianetin, Columbianetin, O-Isovalerylcolumbianetin, Cnidiadin, Archangelicin, Edultin, 2'(S),3'(R)-Isobutyryloxy-O-acetyl-2',3'-dihydrooroselol, Bergapten, Isopimpinellin, Osthol
C. monnieri (*C2):
Cnidimonal, Cnidimarin, 5-Formylxanthotoxol, 2'-Deoxymeranzin hydrate, Osthol, Imperatorin, Isopimpinellin, Bergapten, Xanthotoxin, Xanthotoxol, 5-Hydroxyxanthotoxol, Auraptenol, Murrayacarpin A, Diosmetin, 7-Methoxy-8-formylcoumarin, Meranzin hydrate, Cnindimol B, Alloimperatorin, Cnidimoside

Chemical structure




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Pharmacological effectAntibacterial (fungus, cutaneous mycosis), antiviral (influenza virus, etc.), antiinflammatory, antipruritus (chloroform soluble fraction in methanol extract: *P1).
DNA sequenceAB027243, AB027538
Classical reference
(Chinese Herbal Classic "Zhenglei bencao")
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DiseaseImpotence, Infertility, Lower back pain, Leukorrhea, Itching, Itching of the genital, Eczema
Formulationrarely used in formula
ReferencesJP18: The 18th edition of the Japanese Pharmacopoeia.
CP2020: Pharmacopoeia of the People's Republic of China 2020 edi.
C1)The Encyclopedia of Wakan-Yaku with Color Pictures Vol. I, pp 229-231.
C2)J. Nat. Prod., 63, 485-488 (2000).
P1)Biol. Pharm. Bull., 24, 1012-1015 (2001).
RemarksJapanese Shechuangzi (Wajashoshi, Torilis japonica) is hardly marketable at present.
Last renewal date2024/06/23