Crude drug sample data base

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Crude drug name

Market name益智
Formal name益智
Japanese nameやくち, Yakuchi
Vernacular nameYizhi
Latin nameAlpiniae Fructus (JP), Alpiniae Oxyphyllae Fructus (CP)
English nameBitter Cardamon (JP), Sharpleaf Glangal Fruit (CP)
Other names益智仁（果殻を除く）
Original plant nameAlpinia oxyphylla Miq.
Family nameZingiberaceae
Used partClassificationPlant origin
Sub classification mature fruit
Production area informationPeople's Republic of China, Hainan Prov.
Collection informationJapan, Osaka Pref., Tochimoto Tenkaido Co., Ltd.
Collection date2024/09/19
CollectorMichiko Jo
Remarks(Lot No. 010623001) Library-2025
TMPW No.32225

The capital city, provincial capital city or the representative　　
location of its administrative area is indicated.　　
20.044412
110.19828600000005
Production area information
People's Republic of China,Hainan Prov.
https://ethmed.toyama-wakan.net/img/pin_san.png
34.6937378
135.50216509999996
Collection information
Japan,Osaka Pref.
https://ethmed.toyama-wakan.net/img/pin_nyu.png

Scientific information data base

Common name益智, Yizhi, Alpiniae FructusJP, Alpiniae Oxyphyllae FructusCP, Bitter CardamonJP, Sharpleaf Glangal FruitCP
Synonyms益智仁（果殻を除く）
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Original plant nameAlpinia oxyphylla Miquel
original plant image
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Family nameZingiberaceae
Used partmature fruit
Quality for selectionThe one with large granules, a pale yellow to light yellowish-brown outer surface, and a strong aroma is considered to be of good quality (TN).
Official compendiumJP XIX, CP (2025 ed.)
Clinical applicationIt is used as an aromatic stomachic and intestinal remedy for decreased digestive function, diarrhea associated with indigestion, and nervous diarrhea. It is used in the same way as Amomi Semen (縮砂).
Medical systemTraditional Chinese medicine
Drug effect in
traditional medicine		Traditional
classification		Replenishing Yang(vital function) drugs
Beneficial effect[Property and Flavor] Warm; pungent.
[Meridian Tropism] Spleen and kidney meridians meridians.
[Actions] To warm the kidney to secure essence to reduce urination, when the spleen to check diarrhea and constrain spittle.
[Indications] Kidney deficiency with enuresis, frequent urination, seminal emission and white turbidity, diarrhea caused by spleen cold, cold pain in the abdomen, dribbling.
Chemical constituentMonoterpenoids
(*C1):
1,8-Cineole, beta-Pinene, p-Cymene, Terpinen-4-ol
(*C2):
Camphor

Sesquiterpenoids
*C1):
Zingiberene, beta-Salinene, beta-Caryophyllene, alpha-Humulene, alpha-Copaene, Nootkatone
(*C2):
Zingiberol

Flavonoids
(*C3):
tectochrysin, chrysin, izalpinin, 3,5-dihydroxy-7, 4'-dimethoxyflavone

Diarylheptanoids
(*C1, C2):
Yakuchinone A(1-(4'-hydroxy-3'-methoxyphenyl)-7-phenyl-3-heptanone), Yakuchinone B

Chemical structure


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Pharmacological effectAntiulcer (acetone extract, nootkatone) (P1).
DNA sequenceAF254463
Classical reference
(Chinese Herbal Classic "Zhenglei bencao")		※Click this image to see the actual image
DiseaseAbdominal pain, Chill, Dyspepsia, Diarrhea, Anorexia, Slaver, Spermatorrhea, Frequent urination
Formulationrarely used in formula,
Related drugsAmomi Semen
ReferencesJP: The 19th edition of the Japanese Pharmacopoeia.
CP: Pharmacopoeia of the People's Republic of China 2025 edi.
C1 )The Encyclopedia of Wakan-Yaku with Color Pictures Vol. I, pp 238-239.
C2) Outline of Pharmacognosy, a Textbook, p 322.
C3) Partner Pharmacognosy, p 355.
P1) Chem. Pharm. Bull., 38, 3053(1990)
RemarksThe medicinal benefit of Yizhi resembles "Buguzhi" (補骨脂, Psoraleae Semen). However, "Buguzhi" acts mostly on kidney, while Yizhi acts mostly on spleen. Impotence due to insufficiency of kidney, and knee and lumbar pain with cold symptoms are incurable with Yizhi.
Last renewal date2026/07/17
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