Crude drug sample data base

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Crude drug name

Market nameニガキ
Formal name苦木
Japanese nameにがき, Nigaki
Vernacular nameNigaki
Latin namePicrasmae Lignum (JP), Picrasmae Ramulus et Folium (CP)
English namePicrasma Wood (JP), Indian Quassiawood (CP)
Original plant namePicrasma quassioides Bennet , (Nigaki)
Family nameSimaroubaceae
Used partClassificationPlant origin
Sub classification wood
Collection informationJapan, Osaka Pref., Tochimoto Tenkaido Co.,Ltd.
Collection date1975/04/00
TMPW No.3957

The capital city, provincial capital city or the representative  
location of its administrative area is indicated.  
Production area information
https://ethmed.toyama-wakan.net/img/pin_san.png
34.6937378
135.50216509999996
Collection information
Japan,Osaka Pref.
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Scientific information data base

Common name苦木, Kumu, Picrasmae Lignum (JP18), Picrasmae Ramulus et Folium (CP2020), Picrasma Wood (JP18), Indian Quassiawood (CP2020)
crude drug image
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Original plant namePicrasma quassioides Bennet , (Nigaki)
original plant image
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Family nameSimaroubaceae
Used partwood (without bark)
Quality for selectionGood Kumu has a strong bitterness and no contamination of bark. (TN)
Official compendiumJP XVIII, CP (2020 ed.)
Clinical applicationAs an amaroid stomachic, its powder, tink or decoction is used to treat indigestion, diarrhea and gastroenteritis. It is also insecticidal and good for scabies.
Medical systemTraditional Chinese medicine
Drug effect in
traditional medicine
Traditional
classification
Febrifugal and detoxicant drugs
Beneficial effect[Property and Flavor] Cold; bitter; slighlty toxic.
[Meridian Tropism] Lung and large intestine meridians.
[Actions] To clear heat and remove toxin, and dispel dampness.
[Indications] Common cold caused by wind-heat, swollen sore throat, dampness-heat diarrhea and dysentery, eczema, sore an d deep-rooted boil, bite wound of insect, worm or snake.
Chemical constituentTriterpenoids
(*C1):
Nigakilactone A, Nigakilactone B, Nigakilactone C, Nigakilactone D(=Quassin), Nigakilactone E, Nigakilactone F, Nigakilactone G(= Picrasin A), Nigakilactone H, Nigakilactone I, Nigakilactone J, Nigakilactone K, Nigakilactone L, Nigakilactone M, Nigakilactone N, Nigakihemiacetal A, Nigakihemiacetal C, Neoquassin, Picrasin A, Picrasin B, Picrasin C, Picrasin D, Picrasin E, Picrasin F, Picrasin G

Benzoquinones
(*C1):
2,6-Dimethoxy-p-benzoquinone

Indole alkaloids
(*C1):
Nigakinone, Methylnigakinone, 4,5-Dimethoxycanthin-6-one, beta-Carbolin 誘導体/derivatives

Chemical structure






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DiseaseDyspepsia, Diarrhea, Gastroenteritis
Formulation
Related drugsJamaica quassia, Surinam quassia
ReferencesJP18: The 18th edition of the Japanese Pharmacopoeia.
CP2020: Pharmacopoeia of the People's Republic of China 2020 edi.
C1)The Encyclopedia of Wakan-Yaku with Color Pictures Vol. II, pp 177-178.
RemarksJamaica quassia is the heart wood of Picrasma excelsa Planchon (Jap. name: Jamaicanigaki). Surinam quassia is the heart wood of Quassia amara L. Both are used as an amaroid stomachic. In Japan, Kumu is substituted for these Quassiae Lignums. The branch and leaf are used for removing toxic heat in China.
Last renewal date2021/09/27