Crude drug sample data base
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Scientific information data base
Common name | 蛇床子, Shechuangzi, Cnidii Monnieri Fructus (JP18), Cnidii Fructus (CP2020), Cnidium Monnieri Fruit (JP18), Common Cnidium Fruit (CP2020) | |||||
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Original plant name | Cnidium monnieri Cusson1, Torilis japonica (Houtt.) De Candolle2, (CN products: Okazeri1, JP&KR products: Yabujirami2) | |||||
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Family name | Umbelliferae | |||||
Used part | mature fruit | |||||
Quality for selection | The external surface of good Shechuangzi is yellow-green in color. When it is kneaded by hands, it gives acrid odor strongly. (TN) | |||||
Official compendium | JHMC (1989), JP XVIII, CP (2020 ed.) | |||||
Clinical application | Shechuangzi is an important drug for yin disease of women. As an astringent-antiphlogistic drug, it is applied externally for vulval itching, eczema of scrotum and other eczemas. It is also used for impotence as internally. | |||||
Medical system | Traditional Chinese medicine | |||||
Drug effect in traditional medicine | Traditional classification | External drugs | ||||
Beneficial effect | [Property and Flavor] Warm; pungent, bitter; slightly toxic. [Meridian Tropism] Kidney meridian. [Actions] To dry dampness and dispel wind, kill worms to relieve itching, warm the kidney and invigorate yang. [Indications] Pudendal itch, vaginal discharge, itching caused by eczema, fixed impediment lumbago, impotence caused by kidney deficiency, infertility caused by uterine coldness. | |||||
Chemical constituent | Fatty acids T. japonica (*C1): 脂肪油約 / fatty oil about 10% Petroselinic acid, Myristine, Olein Monoterpenoids C. monnieri (*C1): 精油約 / essential oil about 1.3% l-Pinene, l-Camphene, Bornyl isovalerate Sesquiterpenoids T. japonica (*C1): 精油約 / essential oil about 1.4% alpha-Cadinene, Torilin Coumarins C. monnieri (*C1): Columbianadin, O-Acetylcolumbianetin, Columbianetin, O-Isovalerylcolumbianetin, Cnidiadin, Archangelicin, Edultin, 2'(S),3'(R)-Isobutyryloxy-O-acetyl-2',3'-dihydrooroselol, Bergapten, Isopimpinellin, Osthol C. monnieri (*C2): Cnidimonal, Cnidimarin, 5-Formylxanthotoxol, 2'-Deoxymeranzin hydrate, Osthol, Imperatorin, Isopimpinellin, Bergapten, Xanthotoxin, Xanthotoxol, 5-Hydroxyxanthotoxol, Auraptenol, Murrayacarpin A, Diosmetin, 7-Methoxy-8-formylcoumarin, Meranzin hydrate, Cnindimol B, Alloimperatorin, Cnidimoside | |||||
Chemical structure |
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Pharmacological effect | Antibacterial (fungus, cutaneous mycosis), antiviral (influenza virus, etc.), antiinflammatory, antipruritus (chloroform soluble fraction in methanol extract: *P1). | |||||
DNA sequence | AB027243, AB027538 | |||||
Classical reference (Chinese Herbal Classic "Zhenglei bencao") | ※Click this image to see the actual image | |||||
Disease | Impotence, Infertility, Lower back pain, Leukorrhea, Itching, Itching of the genital, Eczema | |||||
Formulation | rarely used in formula | |||||
References | JP18: The 18th edition of the Japanese Pharmacopoeia. CP2020: Pharmacopoeia of the People's Republic of China 2020 edi. C1)The Encyclopedia of Wakan-Yaku with Color Pictures Vol. I, pp 229-231. C2)J. Nat. Prod., 63, 485-488 (2000). P1)Biol. Pharm. Bull., 24, 1012-1015 (2001). | |||||
Remarks | Japanese Shechuangzi (Wajashoshi, Torilis japonica) is hardly marketable at present. | |||||
Last renewal date | 2024/06/23 | |||||