Crude drug sample data base

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Crude drug name

Market name砂参
Formal name沙参
Japanese nameしゃじん, Shajin
Vernacular nameSasam
Latin nameAdenophorae Radix (JP), (CP)
English nameAdenophora Root (JP), Fourleaf Ladybell Root (CP)
Original plant nameAdenophora sp.
Family nameCampanulaceae
Used partClassificationPlant origin
Sub classification root
Collection informationRepublic of Korea
TMPW No.4376

Scientific information data base

Common name沙参, Shashen, Adenophorae Radix (Non-JPS2022, CP2020), Adenophora Root (Non-JPS2022), Fourleaf Ladybell Root (CP2020)
Synonyms南沙参
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Original plant nameAdenophora tetraphylla Fischer, Adenophora stricta Miquel1, Adenophora hunanensis Nannfeldt or Adenophora triphylla A. De Candolle, (Marubanoninjin1)
original plant image
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Family nameCampanulaceae
Used partroot
Quality for selectionGood Shashen is enlarged and corn shaped. The internal is dense and white. (TN)
Official compendiumNon-JPS (2022), CP (2020 ed.)
Clinical applicationAs an antitussive, expectorant and tonic, shashen is applied for invalid's chronic cough, stridor, phthisis and oliguria.
Medical systemTraditional Chinese medicine
Drug effect in
traditional medicine
Traditional
classification
Drugs for replenishing Yin-vital essence
Beneficial effect[Property and Flavor] Mild cold; sweet.
[Meridian Tropism] Lung and stomach meridians.
[Actions] To nourish yin, clear heat, boost the stomach, engender fluid, resolve phlegm, and tonify qi.
[Indications] Lung heat and dry cough, cough caused by yin consumptive disease, dry cough with greasy phlegm, stomach yin deficiency, reduced food intake, vomiting, deficiency of qi and yin, heat vexation and dry mouth.
Chemical constituentTriterpenoids
A. stricta subsp. sessilifolia (*C1):
Sessilifolic acid 3-O isovalerate, Lupenone, 24-Methylene cycloartanol

Sterols
A. stricta subsp. sessilifolia (*C1):
beta-Sitosteryl pentadecanoate, beta-Sitosteryl palmitate, beta-Sitosterol, Ikshusterol, beta-Sitosteryl glucoside

Pharmacological effectNot exactly known
DNA sequenceAF090712, AF090713; Traditioal Medical & Parmaceutical Database.
Classical reference
(Chinese Herbal Classic "Zhenglei bencao")
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DiseaseCough, Dry cough, Thirst, Fever, Chronic bronchitis
Formulationrarely used in formula
Related drugsBeishashen (binfangfeng), Manshen (see "Remarks")
ReferencesNon-JPS2022: The Japanese standards for non-Pharmacopoeial crude drugs 2022.
CP2020: Pharmacopoeia of the People's Republic of China 2020 edi.
C1) Shoyakugaku Zasshi,44,98-100(1990).
RemarksChinese "Shashen" consists of southern and northern "Shashen". Southern "Shashen" is from the plants of family Campanulaceae of genus Adenophora and northern "Shashen" is the barked root of Glehnia littoralis Fr. Schmidt et Miquel of family Umbelliferae (Jap. name: Hamabohu). Southern "Shashen" has strong behavior of removing phlegm, while northern "Shashen" has strong effect of nourishing Yin.
Korean "Shashen" is the root of Codonopsis lanceolata (Sieb. et Zucc.) Trautv. of family Campanulaceae. In Korea, this species is called "Totok" which is the origin of Japanese "Totoki". Japanese "Shashen" is mostly the root of Adenophora triphylla A.DC. var. japonica Hara (Jap. name: Tsuriganeninjin).
Last renewal date2022/07/19