Crude drug sample data base

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Crude drug name

Market name紅芽大戟
Formal name紅芽大戟
Japanese nameこうがたいげき, Kōgataigeki
Vernacular nameHongyadaji
Latin nameKnoxiae Radix (CP)
English nameKnoxia Root (CP)
Original plant nameKnoxia valerianoides Thorel et Pitard
Family nameRubiaceae
Used partClassificationPlant origin
Sub classification root
Collection informationPeople's Republic of China, Beijing, Beijing Medical University
Collection date1981/03/02
CollectorTsuneo Namba
TMPW No.44

The capital city, provincial capital city or the representative  
location of its administrative area is indicated.  
Production area information
Collection information
People's Republic of China,Beijing

Scientific information data base

Common name紅芽大戟, Hongyadaji, Knoxiae Radix (CP2020), Knoxia Root (CP2020)
Synonyms紅大戟, 大戟
crude drug image
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Original plant nameKnoxia valerianoides Thorel ex Pitard
Family nameRubiaceae
Used partroot
Official compendiumCP (2020 ed.)
Clinical applicationAs an antidote, laxative and for curing sores, Hongyadaji is applied for dropsy, a feeling of fullness in the chest, retention of phlegm, carbuncles and sores.
Medical systemTraditional Chinese medicine
Drug effect in
traditional medicine
Purgatives for removing water retention
Beneficial effect[Property and Flavor] Cold; bitter; slightly toxic.
[Meridian Tropism] Lung, spleen and kidney meridians.
[Actions] To expel retained fluid by purgation, disperse swelling and dissipate binds.
[Indications] Edema distention and fullness, hydrothorax and ascites, phlegm-fluid retention, aggregation and accumulation, cough and panting caused by qi counterflow, inhibited of defecation and urination, swelling abscess, sore and toxin, scrofula and phlegm nodule.
Chemical constituentAnthraquinones
アントラキノン誘導体/Anthraquinone derivatives

Pharmacological effectNot exactly known.
DNA sequenceAJ288631
Classical reference
(Chinese Herbal Classic "Zhenglei bencao")
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DiseaseAscites, Edema, Oliguria, Constipation, Pleural effusion, Pain due to flatulence of hypochondrium, Pyogenic dermatosis, Cervical lymphadenopathy, Subcutaneous nodule
Formulationrarely used in formula
Related drugsJingdaji: the root of Euphorbia pekinensis Rupr. of family Euphorbiaceae, Caodaji: the root of Lespedeza sp. of family Leguminosae
ReferencesCP2020: Pharmacopoeia of the People's Republic of China 2020 edi.
C1)The Encyclopedia of Wakan-Yaku with Color Pictures Vol. I, p 14-15.
RemarksAt present, three species of Daji (大戟) are distributed in China, Hongyadaji (紅芽大戟) of family Rubiaceae, Caodaji (草大戟) of family Leguminosae and Jingdaji (京大戟) of family Euphorbiaceae. Though each plant belongs to a different family, they are all called Daji. By nature, the real Daji described in materia medicas is Jingdaji. However, only Hongyadaji is imported to Japan at present.
Jingdaji: the root of Euphorbia pekinensis Rupr. of family Euphorbiaceae. Once, it was used in Jiangsu Prov., Shanghai city and a part of Anwhei Province. In an area of Jiangsu Prov., the root of Indigofera sp. of family Leguminosae is used as Caodaji.
Last renewal date2021/09/27