Crude drug sample data base
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Crude drug name | Market name | 苦楝子 |
|---|---|---|
| Formal name | 川楝子 | |
| Japanese name | せんれんし, Senrenshi | |
| Vernacular name | Chuanlianzi | |
| Latin name | Meliae Fructus (Non-JPS), Toosendan Fructus (CP) | |
| English name | Melia Fruit (Non-JPS), Szechwan Chinaberry Fruit (CP) | |
| Original plant name | Melia azedarach L. var. toosendan (Sieb. et Zucc.) Makino, (Tōsendan) | |
| Family name | Meliaceae | |
| Used part | Classification | Plant origin | Sub classification | mature fruit |
| Collection information | People's Republic of China, Chengdu , Hehuachi Market, Chengdu | |
| Collection date | 1986/06/14 | |
| Collector | Tsuneo Namba | |
| TMPW No. | 4581 | |
The capital city, provincial capital city or the representative
location of its administrative area is indicated.
location of its administrative area is indicated.
Production area information
https://ethmed.toyama-wakan.net/img/pin_san.png
30.572815
104.06680099999994
Collection information
People's Republic of China,Chengdu
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Scientific information data base
| Common name | 川楝子, Chuanlianzi, Meliae Fructus (Non-JPS2022), Toosendan Fructus (CP2020), Melia Fruit (Non-JPS2022), Szechwan Chinaberry Fruit (CP2020) | |||||
|---|---|---|---|---|---|---|
| Synonyms | 苦楝子（Kulianzi） | |||||
| crude drug image |
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| Original plant name | Melia toosendan Siebold et Zuccarini1 or Melia azedarach Linn. var. subtripinnata Miquel2 , (Tōsendan1, Sendan2) | |||||
| original plant image |
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| Family name | Meliaceae | |||||
| Used part | mature fruit | |||||
| Official compendium | CP (2020 ed.), Non-JPS (2022) | |||||
| Clinical application | As an anthelmintic and analgesic, it is applied to treat colic caused by ascaridiasis, stomach and abdominal pain. | |||||
| Medical system | Traditional Chinese medicine | |||||
| Drug effect in traditional medicine | Traditional classification | Carminatives for regulating flow of Qi | ||||
| Beneficial effect | [Property and Flavor] Cold; bitter; slighlty toxic. [Meridian Tropism] Liver, small intestine and bladder meridians. [Actions] To soothe the liver and discharge heat, move qi to relieve pain, kill worms. [Indications] Depressed liver qi transforming into fire, distending pain in the chest, hypochondrium, epigastrium and abdomen, pain caused by genital disease, abdominal pain caused by worm accumulation. | |||||
| Chemical constituent | Triterpenoids M. azedarach (*C1,C6-C19): Meldenin, Nimbinin, Melianin A, Melianol, Melianone, Meliatoxin A1, Meliatoxin A2, Meliatoxin B1, Meliatoxin B2, Melianotriol, Melianodiol, Nimbolidin A, Nimbolidin B, Nimbolin A, Nimbolin B, Azedarachol, Kulactone, Kulinone, Sendanolactone, Sendandal, Sendanin M. toosendan (*C2-C4): 21-O-Acetyltoosendantriol, 21-O-Methyltoosendanpentol, Lipomelianol Others M. toosendan (*C5): Meliainoside A, Meliainoside B M. azedarach (C13,C20,C21): Nimbolinin A, Nimbolinin B, Ohchinolide A, Ohchinolide B, Ohchinal Ohchinin, Ohchinin acetate, Ohchinolal | |||||
| Chemical structure |     
※画像をクリックすると、拡大して表示されます。 | |||||
| Pharmacological effect | It has a strong larvicidal action on pig roundworms, earthworms and bloodsuckers in vitro. Rat pinworms (Aspicularis tetraptera) were killed completely by the 25% solution within 12 hours. Its preparation was effective in a stomachache clinically. Its oil ointment was also effective in Trichophyton of head. | |||||
| Classical reference (Chinese Herbal Classic "Zhenglei bencao") |  ※Click this image to see the actual image | |||||
| Disease | Roundworm, Enterobiasis, Stomachache, Lower abdominal pain, Restlessness, Feeling of bitter in the mouth, Thirst, Dryness of tongue, Scrotal shrinkage, Swelling and pain of testis, Pain of testis | |||||
| Formulation | Shobaito | |||||
| Related drugs | Kulianpi (Chuanlianpi) = Melia bark, Nimba (Neem) | |||||
| References | Non-JPS2022: The Japanese standards for non-Pharmacopoeial crude drugs 2022. CP2020: Pharmacopoeia of the People's Republic of China 2020 edi. C1)The Encyclopedia of Wakan-Yaku with Color Pictures Vol. I, pp 247-248. C2)Chem. Lett., 69 (1986). C3)Heterocycles, 28, 383 (1989). C4)Chem. Pharm. Bull., 34, 100 (1986). C5)Chem. Pharm. Bull., 39, 2529 (1991). C6)J. Chem. Soc., Perkin Trans., 1, 1352 (1975). C7)J. Chem. Soc. C., 820 (1967). C8)Chem. Pharm. Bull., 40, 1053 (1992). C9)J. Am. Chem. Soc., 103, 1228 (1981). C10)Phytochemistry, 22, 531 (1983). C11)J. Chem. Soc., Chem. Commun., 910 (1967). C12)J. Chem. Soc., Chem. Commun., 261 (1971). C13)Chem. Ber., 114, 267 (1981). C14)J. Chem. Soc., Chem. Commun., 1166 (1969). C15)Phytochemistry, 24, 1945 (1985). C16)Tetrahedron, 29, 1911 (1973). C17)Bull. Chem. Soc. Jpn., 50, 2499 (1977). C18)Chem. Lett., 621 (1978). C19)Tetrahedron Lett., 2877 (1976). C20)Chem. Lett., 331 (1978). C21)Bull. Chem. Soc. Jpn., 56, 1139 (1983). | |||||
| Remarks | In case Chuanlianzi derived from Melia toosendan Sieb. et Zucc. (Jap. name: Tōsendan) was insufficient, the fruit of congener M. azedarach L. var. azedarach (Jap. name: Tokiwasendan) is sometimes substituted for it. The fruit of M. azedarach L. var. subtripinnata Miq., Japanese Sendan, is not available in the market. Kurenpi is the bark or root bark of Tōsendan or Tokiwasendan. Though it has the same effects as Chuanlianzi, the bark has stronger insecticidal effect and the fruit has stronger analgesic effect. Nimba is Melia azadirachta L. (= Azadirachta indica A. Juss.). It is a typical Ayurvedic drug and the parts used are the bark, leaf, flower, fruit and seed. | |||||
| Last renewal date | 2022/07/20 | |||||
