Crude drug sample data base

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Crude drug name

Market name青木香
Formal name青木香
Japanese nameせいもっこう, Seimokkō
Vernacular nameQingmuxiang
Latin nameRadix Aristolochiae (CP1995)
English nameDutchmanspipe Root
Original plant nameAristolochia debilis Sieb. et Zucc.1, Aristolochia contorta Bunge2, (Umanosuzukusa1, Marubanoumanosuzukusa2)
Family nameAristolochiaceae
Used partClassificationPlant origin
Sub classification root
Collection informationPeople's Republic of China, Chengdu, Hehuachi Market, Chengdu
Collection date1986/06/14
CollectorTsuneo Namba, et al.
TMPW No.4630

The capital city, provincial capital city or the representative  
location of its administrative area is indicated.  
Production area information
https://ethmed.toyama-wakan.net/img/pin_san.png
30.572815
104.06680099999994
Collection information
People's Republic of China,Chengdu
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Scientific information data base

Common name青木香, Qingmuxiang, Radix Aristolochiae (CP1995)
Synonyms南木香, 土青木香
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Original plant nameAristolochia debilis Sieb. et Zucc.1, Aristolochia contorta Bunge2, (Umanosuzukusa1, Marubanoumanosuzukusa2)
Family nameCompositae
Used partroot
Official compendiumCP (1995 ed.)
Clinical applicationAs an analgesic, anti-inflammatory and antidote, it is applied to distending pain in the chest, hypochondrium, epigastrium and abdomen. It is also used for colic pain, pain due to swelling, insect or snake bites and hypertension.
Medical systemTraditional Chinese medicine
Drug effect in
traditional medicine
Traditional
classification
Carminatives for regulating flow of Qi
Beneficial effect[Property and Flavor] Warm; bitter.
[Meridian Tropism] Liver, spleen and kidney meridians.
[Actions] To remove qi and activate blood, unblock the collaterals to relieve pain.
[Indications] Stabbing pain in the epigastrium and abdomen, painful impediment caused by wind-dampness.
Chemical constituentSesquiterpenoids
A. debilis (*C1-C3):
1(10)-Aristolen-12-al, Aristolone, Aristoic acid, 9alpha-Hydroperoxy-1(10)-aristolen-2-one, 1alpha-Hydroxy-9-aristolen-8-one, Debilone, 3-Ishwaranone

Alkaloids
A. debilis (*C1,C5-C7):
Aristolochic acid C, 7-Hydroxyaristolochic acid A, Aristolochic acid II, 7-Methoxyaristolochic acid A, Aristololactam I, Debilic acid, Cyclanoline
A. contorta (*C4):
Aristochic acid E

Other nitrogen compounds
A. debilis (*C1):
Allantoin

Chemical structure



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Pharmacological effectDecrease in blood pressure.
Classical reference
(Chinese Herbal Classic "Zhenglei bencao")
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DiseaseFull stomach, Abdominal pain, Arthralgia, Edema, Hypertension
FormulationUreitsukito, Kagenshosaikoto, Kamikihito, Kikyoto, Kihito, Kyukihochuto, Kumibinroto, Kobokuto, Kowashakuyakuto, Goshitsusan, Sanshoin, Shichimibyakujutsuto, Jippito, Shakuyakuto, Jurokumiryukiin, Shobaito, Jinsoin, Zenshikunshito, Zenshibyakujutsusan, Chuseito, Chokoshiteito, Dosuibukuryoto, Dotaitsukeito, Naisoorento, Nyoshinsan, Haikanpo, Baimoto, Bunshoto, Boisan, Boito, Botanpisan, Honposhakuyakuto, Rogyokuto, Koshayoito
Related drugsSaussureae Radix, Vladimiriae Radix, Inulae Radix, Aristolochiae Fructus
ReferencesCP1995: Pharmacopoeia of the People's Republic of China 1995 edi.
C1)The Encyclopedia of Wakan-Yaku with Color Pictures Vol. I, pp 40-42.
C2)Phytochemistry, 23, 1647 (1984).
C3)Agric. Biol. Chem., 37, 341(1973).
C4)Yaoxue Xuebao, 21, 702 (1986).
C5)Yakugaku Zasshi, 79, 973 (1959).
C6)Huaxue Xuebao, 39, 237 (1981).
C7)Kexue Tongbao, 761, (1957).
RemarksThe real Muxiang (木香) is the root of Saussurea lappa Clarke (= Aucklandia lappa Decne.) of family Compositae, which was called Qingmuxiang (Jap. name: 青木香, Seimokkō) in ancient times.
At present, it is the root of Aristolochia debilis Sieb. et Zucc. (Jap. name: Umanosuzukusa) and A. contorta Bunge (Jap. name: Marubaumanosuzukusa) of family Aristolochiaceae. The aerial part of these two species are called Tianxianteng (天仙藤, Aristolochiae Herba) in China. It is used for promoting circulation of qi and blood, inducing diuresis and removing edema. It is applied to treat stomachache, abdominal pain, aching joints and edema in pregnancy. Qingmuxiang was listed in the Chinese Pharmacopoeia (1995 edi.) but it was excluded from its 2000 edi. Tianxianteng was also excluded from its 2020 edi.
Meantime, Qingmuxiang and Tianxianteng contain aristolochic acid, which may cause renal damage according to reports. Therefore it must be prescribed with care.
Last renewal date2021/09/28